It’s only fair to share… Velagliflozin 2-[(4-cyclopropylphenyl)methyl]-4-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]benzonitrile Velagliflozin L-proline H2O Velagliflozin, sold under the brand name Senvelgo, is an antidiabetic medication used for the treatment of cats.[2][4][5] Velagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor.[6] It is taken by mouth.[2] Velagliflozin is the active ingredient of the first oral liquid medication approved by the Food and Drug Administration for the treatment of …
Category «FDA 2023»
Vamorolone
It’s only fair to share… Vamorolone CAS 13209-41-1 Molecular Weight 356.46 Formula C22H28O4 Vamorolone (VBP15) is a first-in-class, orally active dissociative steroidal anti-inflammatory agent and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone shows potent NF-κB inhibition and substantially reduces hormonal effects. Vamorolone, sold under the brand name Agamree, is a synthetic corticosteroid, which is used for the treatment of Duchenne muscular …
BEXAGLIFLOZIN
It’s only fair to share… BexagliflozinTHR1442; THR-1442, EGT 0001442; EGT1442CAS :1118567-05-7(2S,3R,4R,5S,6R)-2-[4-chloro-3-({4-[2- (cyclopropyloxy) ethoxy] phenyl} methyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H- pyran-3,4,5-triol D-Glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-, (1S)- (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 1-[4-Chloro-3-[4-[2-(cyclopropyloxy)ethoxy]benzyl]phenyl]-1-deoxy-beta-D-glucopyranose1,5-Anhydro-1(S)-[4-chloro-3-[4-[2-(cyclopropyloxy)ethoxy]benzyl]phenyl]-D-glucitol (1S)-1,5-anhydro-1-C-[4-chloro-3-({4-[2- (cyclopropyloxy)ethoxy]phenyl}methyl)phenyl]-D-glucitol Chemical Formula: C24H29ClO7Exact Mass: 464.16018 Mechanism of Action:SGLT2 inhibitor, Sodium-glucose transporter 2 inhibitorsIndication:Type 2 diabetes FDA APPROVED 1/20/2023 Brenzavvy To improve glycemic control in adults with type 2 diabetes mellitus as an …
Gepirone
It’s only fair to share… Gepirone CAS 83928-76-1 BMY 13805, MJ 13805, ORG 13011, Gepirona, JW5Y7B8Z18 FDA 9/22/2023, Gepirone is indicated for the treatment of major depressive disorder (MDD) in adults Exxua WeightAverage: 359.474Monoisotopic: 359.232125194Chemical FormulaC19H29N5O2 4,4-dimethyl-1-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}piperidine-2,6-dione Ingredient UNII CAS InChI Key Gepirone Hydrochloride 80C9L8EP6V 83928-66-9 DGOCVISYYYQFEP-UHFFFAOYSA-N Gepirone, sold under the brand name Exxua, is a medication used …
Lotilaner
It’s only fair to share… Lotilaner 3-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]thiophene-2-carboxamide FDA Xdemvy, 7/25/2023, To treat Demodex blepharitisDrug Trials Snapshot Lotilaner, sold under the brand name Xdemvy, is an ectoparasiticide (anti-parasitic) medication used for the treatment of blepharitis (inflammation of the eyelid) caused by infestation by Demodex (tiny mites).[1][7] It is used as an eye drop.[1] It was approved for medical use in the United States in July 2023.[1][7][8][9] The US Food …
Flotufolastat F 18
It’s only fair to share… Flotufolastat F 18 gallium;2-[7-[(1S)-1-carboxy-4-[[(2R)-1-[[(1R)-1-carboxy-5-[[4-[[(4R)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(1S)-1,3-dicarboxypropyl]carbamoylamino]butanoyl]amino]butyl]amino]-4-oxobutanoyl]amino]pentyl]amino]-3-[[4-[ditert-butyl(fluoranyl)silyl]benzoyl]amino]-1-oxopropan-2-yl]amino]-4-oxobutyl]-4,10-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate WeightAverage: 1470.63Monoisotopic: 1469.662295938 Chemical FormulaC63H99FN12O25Si 2639294-14-5 CAS FDA 2023, Posluma, 5/25/2023, To use with positron emission tomography imaging in certain patients with prostate cancerDrug Trials Snapshot Flotufolastat (18F), sold under the brand name Posluma, is a radioactive diagnostic agent for use with positron emission tomography (PET) imaging for prostate cancer.[1] The active ingredient is flotufolastat …
Durlobactam
It’s only fair to share… Durlobactam CAS 1467829-71-5 WeightAverage: 277.25Monoisotopic: 277.03685626 Chemical FormulaC8H11N3O6S Ingredient UNII CAS InChI Key Durlobactam sodium F78MDZ9CW9 1467157-21-6 WHHNOICWPZIYKI-IBTYICNHSA-M FDA 5/23/2023, Xacduro, To treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia caused by susceptible isolates of Acinetobacter baumannii-calcoaceticus complexPress ReleaseDrug Trials Snapshots (2S,5R)-2-CARBAMOYL-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL SULFATE SULFURIC ACID, MONO((2S,5R)-2-(AMINOCARBONYL)-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL) ESTERETX 2514, ETX-2514, ETX2514, WHO …
Sulbactam
It’s only fair to share… Sulbactam Ingredient UNII CAS InChI Key Sulbactam benzathine 49MU89FVBV 83031-43-0 YSEPFTSCLHUBNH-HFKSPEPWSA-N Sulbactam sodium DKQ4T82YE6 69388-84-7 NKZMPZCWBSWAOX-IBTYICNHSA-M 68373-14-8 (free acid) WeightAverage: 233.242Monoisotopic: 233.035793157 Chemical FormulaC8H11NO5S (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Betamaze, Penicillanic Acid Sulfone, Sulbactamum, CP 45899, CP-45899, CP45899 FDA 2023, Xacduro, 5/23/2023, To treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia caused by …
Perfluorhexyloctane
It’s only fair to share… WeightAverage: 432.269Monoisotopic: 432.112266666Chemical FormulaC14H17F13 Perfluorhexyloctane 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane FDA APPROVED 8/16/2023, Sohonos, To reduce the volume of new heterotopic ossification in adults and pediatric patients (aged 8 years and older for females and 10 years and older for males) with fibrodysplasia ossificans progressivaDrug Trials Snapshot Perfluorohexyloctane is a fluoroalkane that is tetradecane in which …
Tofersen
It’s only fair to share… all-P-ambo-2′-O-(2-Methoxyethyl)-5-methyl-P-thiocytidylyl-(3’→5′)-2′-O-(2-methoxyethyl)adenylyl-(3’→5′)-2′-O-(2-methoxyethyl)-P-thioguanylyl-(3’→5′)-2′-O-(2-methoxyethyl)guanylyl-(3’→5′)-2′-O-(2-methoxyethyl)-P-thioadenylyl-(3’→5′)-P-thiothymidylyl-(3’→5′)-2′-deoxy-P-thioadenylyl-(3’→5′)-2′-deoxy-5-methyl-P-thiocytidylyl-(3’→5′)-2′-deoxy-P-thioadenylyl-(3’→5′)-P-thiothymidylyl-(3’→5′)-P-thiothymidylyl-(3’→5′)-P-thiothymidylyl-(3’→5′)-2′-deoxy-5-methyl-P-thiocytidylyl-(3’→5′)-P-thiothymidylyl-(3’→5′)-2′-deoxy-P-thioadenylyl-(3’→5′)-2′-O-(2-methoxyethyl)-5-methylcytidylyl-(3’→5′)-2′-O-(2-methoxyethyl)-P-thioadenylyl-(3’→5′)-2′-O-(2-methoxyethyl)guanylyl-(3’→5′)-2′-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3’→5′)-2′-O-(2-methoxyethyl)-5-methyluridine C230H317N72O123P19S15 : 7127.86[2088232-70-4] Tofersen CAS 2088232-70-4 FDA APPROVED 4/25/2023, Qalsody To treat amyotrophic lateral sclerosis in adults who have a SOD1 gene mutationDrug Trials Snapshot A nucleic acid-based drug indicated for the treatment of a specific type of amyotrophic lateral sclerosis. Tofersen, sold under the brand name Qalsody, is a medication used for the …