It’s only fair to share… Difamilast PMDA Moizerto, JAPAN APPROVED 2021/9/27 ジファミラスト ディファミラスト; 地法米司特 N-({2-[4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl]-1,3- oxazol-4-yl}methyl)-2-ethoxybenzamide OPA-15406 Formula C23H24F2N2O5 CAS 937782-05-3 Mol weight 446.4439 MM 36; MM-36-Medimetriks-Pharmaceuticals; Moizerto; OPA-15406 Efficacy Anti-inflammatory, Phosphodiesterase IV inhibitor Comment Treatment of atopic dermatitis OriginatorOtsuka Pharmaceutical Development & Commercialization DeveloperMedimetriks Pharmaceuticals; Otsuka Pharmaceutical Development & Commercialization ClassBenzamides; Nonsteroidal anti-inflammatories; Oxazoles; Skin disorder …
Category «japan 2021»
Avacopan
It’s only fair to share… Avacopan アバコパン авакопан [Russian] [INN] أفاكوبان [Arabic] [INN] 阿伐可泮 [Chinese] [INN] Formula C33H35F4N3O2 CAS 1346623-17-3 Mol weight 581.6435 (2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]piperidine-3-carboxamide (2R,3S)-2-(4-Cyclopentylaminophenyl)-l-(2-fluoro-6-methylbenzoyl)piperidine-3- carboxylic acid (4-methyl-3-trifluoromethylphenyl)amide 3-Piperidinecarboxamide, 2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]-, (2R,3S)- (2R,3S)-2-[4-(Cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]-3-piperidinecarboxamide (2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl3-(trifluoromethyl)phenyl]piperidine-3-carboxamide APPROVED PMDA JAPAN 2021/9/27, Tavneos Anti-inflammatory, Complement C5a receptor antagonist Treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis Avacopan (2R,3S)-2-[4-(Cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]piperidine-3-carboxamide C33H35F4N3O2 : 581.64 [1346623-17-3] CCX 168 Avacopan wasunder investigation in clinical trial …
Upacicalcet sodium hydrate
It’s only fair to share… Upacicalcet sodium hydrate, ウパシカルセトナトリウム水和物 CAS 2052969-18-1 1333218-50-0 free PMDA JAPAN APPROVED 2021/6/23, Upasita Calcium sensing receptor agonist (2S)-2-amino-3-[(3-chloro-2-methyl-5-sulfophenyl)carbamoylamino]propanoic acid Formula C11H13ClN3O6S. Na. xH2O OriginatorAjinomoto Pharma DeveloperSanwa Kagaku Kenkyusho ClassAmines; Chlorobenzenes; Propionic acids; Small molecules; Sulfonic acids; Toluenes Mechanism of ActionCalcium-sensing receptor agonists RegisteredSecondary hyperparathyroidism 25 Jun 2021Chemical structure information added 23 Jun …
Imeglimin hydrochloride
It’s only fair to share… Meglimin hydrochloride Twymeeg Formula C6H13N5. HCl CAS 775351-61-6 (HCl). , C6H14ClN5 191.66 CAS 775351-65-0, FREEFORM 155.20 Mol weight 191.6619 AntidiabeticAPPROVED PMDA JAPAN2021/6/23, イメグリミン塩酸塩 (4R)-6-N,6-N,4-trimethyl-1,4-dihydro-1,3,5-triazine-2,6-diamine DB12509 NCGC00378621-02 HY-14771 Q6003719 UNII-UU226QGU97 UU226QGU97 1,3,5-Triazine-2,4-diamine,1,6-dihydro-N,N,6-trimethyl-,(+)-(9CI) (4R)-6-N,6-N,4-trimethyl-1,4-dihydro-1,3,5-triazine-2,6-diamine Imeglimin [INN] Emd 387008 (R-imeglimin) HCl EMD-387008 Imeglimin is an experimental drug being developed as an oral anti-diabetic.[1][2] It is an oxidative phosphorylation blocker that …
Tucidinostat, Chidamide
It’s only fair to share… Tucidinostat, Chidamide ツシジノスタット 2021/6/23 PMDA JAPAN APPROVED, Hiyasta Formula C22H19FN4O2 CAS 1616493-44-7 Mol weight 390.4103 Antineoplastic, Histone deacetylase inhibitor Chidamide (Epidaza) is a histone deacetylase inhibitor (HDI) developed in China.[1] It was also known as HBI-8000.[2] It is a benzamide HDI and inhibits Class I HDAC1, HDAC2, HDAC3, as well as Class IIb HDAC10.[3] Chidamide is approved by the Chinese FDA for …
Pabinafusp alfa
It’s only fair to share… (Heavy chain) EVQLVQSGAE VKKPGESLKI SCKGSGYSFT NYWLGWVRQM PGKGLEWMGD IYPGGDYPTY SEKFKVQVTI SADKSISTAY LQWSSLKASD TAMYYCARSG NYDEVAYWGQ GTLVTVSSAS TKGPSVFPLA PSSKSTSGGT AALGCLVKDY FPEPVTVSWN SGALTSGVHT FPAVLQSSGL YSLSSVVTVP SSSLGTQTYI CNVNHKPSNT KVDKKVEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKGS SETQANSTTD ALNVLLIIVD DLRPSLGCYG …
Diclofenac etalhyaluronate sodium
It’s only fair to share… Diclofenac etalhyaluronate sodium RN: 1398396-25-2 UNII: LG1II3835L Molecular Formula, [(C30-H35-Cl2-N3-O12)a-(C14-H20-N-Na-O11)b]n-H2-O Molecular Weight, 1101.8195 HYALURONIC ACID PARTLY AMIDIFIED WITH 2-(2-(2-((2,6-DICHLOROPHENYL)AMINO)PHENYL)ACETYLOXY)ETHANAMINE, SODIUM SALT HYALURONAMIDE, N-(2-((2-(2-((2,6-DICHLOROPHENYL)AMINO)PHENYL)ACETYL)OXY)ETHYL), SODIUM SALT SI 613 APPROVED PMDA JAPAN 2021/3/23, Joycle Anti-inflammatory, Joint function improving agent Treatment of Signs and Symptoms of Osteoarthritis of the Knee Diclofenac Etalhyaluronate Sodium Sodium hyaluronate partially …
Anamorelin hydrochloride
It’s only fair to share… Anamorelin 249921-19-5 [RN] 3-{(2R)-3-{(3R)-3-Benzyl-3-[(trimethylhydrazino)carbonyl]-1-piperidinyl}-2-[(2-methylalanyl)amino]-3-oxopropyl}-1H-indole 3-Piperidinecarboxylic acid, 1-[(2R)-2-[(2-amino-2-methyl-1-oxopropyl)amino]-3-(1H-indol-3-yl)-1-oxopropyl]-3-(phenylmethyl)-, 1,2,2-trimethylhydrazide, (3R)- 8846 анаморелин أناموريلين 阿那瑞林 Formula C31H42N6O3 Molar mass 546.716 g·mol−1 .HCL Anamorelin hydrochloride 3-Piperidinecarboxylic acid, 1-[(2R)-2-[(2-amino-2-methyl-1-oxopropyl)amino]-3-(1H-indol-3-yl)-1-oxopropyl]-3-(phenylmethyl)-, 1,2,2- trimethylhydrazide, hydrochloride (1:1), (3R)- Formula C31H42N6O3. HCl CAS 861998-00-7 Mol weight 583.1645 APPROVED JAPAN PMDA Adlumiz, 22/1/2021 アナモレリン塩酸塩 ONO-7643, RC-1291, ST-1291 Antineoplastic, Growth hormone secretagogue receptor (GHSR) agonist Anamorelin is …
Tozinameran, Pfizer–BioNTech COVID‑19 vaccine
It’s only fair to share… SEQUENCE 1gagaauaaac uaguauucuu cuggucccca cagacucaga gagaacccgc 51caccauguuc guguuccugg ugcugcugcc ucuggugucc agccagugug 101ugaaccugac caccagaaca cagcugccuc cagccuacac caacagcuuu 151accagaggcg uguacuaccc cgacaaggug uucagaucca gcgugcugca 201cucuacccag gaccuguucc ugccuuucuu cagcaacgug accugguucc 251acgccaucca cguguccggc accaauggca ccaagagauu cgacaacccc 301gugcugcccu ucaacgacgg gguguacuuu gccagcaccg agaaguccaa 351caucaucaga ggcuggaucu ucggcaccac acuggacagc aagacccaga 401gccugcugau cgugaacaac gccaccaacg uggucaucaa agugugcgag 451uuccaguucu gcaacgaccc cuuccugggc gucuacuacc …