Category «ANTI FUNGAL»

AMOROLFINE

It’s only fair to share…   AMOROLFINE (2R,6S)-2,6-Dimethyl-4-{2-methyl-3-[4-(2-methyl-2-butanyl)phenyl]propyl}morpholine (2R,6S)-2,6-Dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine 78613-35-1 [RN] (±)-cis-2,6-Dimethyl-4-(2-methyl-3-(p-tert-pentylphenyl)propyl)morpholine Ro 14-4767-002 аморолфин , أمورولفين  ,阿莫罗芬  , Title: Amorolfine CAS Registry Number: 78613-35-1 CAS Name:cis-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine Additional Names:cis-4-[3-(4-tert-amylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine; (±)-cis-2,6-dimethyl-4-[2-methyl-3-(p-tert-pentylphenyl)propyl]morpholine Manufacturers’ Codes: Ro-14-4767/000 Molecular Formula: C21H35NO Molecular Weight: 317.51 Percent Composition: C 79.44%, H 11.11%, N 4.41%, O 5.04% Literature References: Antimycotic morpholine derivative; inhibits fungal ergosterol biosynthesis. Prepn (unspec stereochem): A. Pfiffner, K. …

SULCONAZOLE

It’s only fair to share…   SULCONAZOLE сульконазол , سولكونازول , 硫康唑 Molecular FormulaC18H15Cl3N2S Average mass397.749 Da 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]- [ACD/Index Name] 4332 5D9HAA5Q5S 61318-90-9 [RN] (±)-1-[2,4-Dichloro-b-[(p-chlorobenzyl)thio]phenethyl]imidazole 1-[2-[[(4-Chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole : Sulconazole CAS Registry Number: 61318-90-9 CAS Name: 1-[2-[[(4-Chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole Additional Names: (±)-1-[2,4-dichloro-b-[(p-chlorobenzyl)thio]phenethyl]imidazole Molecular Formula: C18H15Cl3N2S Molecular Weight: 397.75 Percent Composition: C 54.35%, H 3.80%, Cl 26.74%, N 7.04%, S 8.06% Literature References: Prepn: K. A. M. Walker, DE2541833; idem,US4055652 (1976, 1977 both to …

CICLOPIROX

It’s only fair to share… Molecular FormulaC12H17NO2 Average mass207.269 Da CICLOPIROX (6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone) 2(1H)-Pyridinone, 6-cyclohexyl-1-hydroxy-4-methyl- 249-577-2 [EINECS] 29342-05-0 [RN] KS-5085, циклопирокс , سيكلوبيروكس , 环吡酮 ,  Ciclopirox CAS Registry Number: 29342-05-0 CAS Name: 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone Molecular Formula: C12H17NO2 Molecular Weight: 207.27 Percent Composition: C 69.54%, H 8.27%, N 6.76%, O 15.44% Literature References: Broad spectrum antimycotic agent with some antibacterial activity. Prepn: G. Lohaus, W. Dittmar, ZA 6906039; eidem, US 3883545 (1970, 1975 both …

OTESECONAZOLE

It’s only fair to share… OTESECONAZOLE VT 1161 (2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(tetrazol-1-yl)-1-[5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl]propan-2-ol C23H16F7N5O2   527.4 Synonyms VT 1161 Oteseconazole 1340593-59-0 Other Names (αR)-α-(2,4-Difluorophenyl)-β,β-difluoro-α-(1H-tetrazol-1-ylmethyl)-5-[4-(2,2,2-trifluoroethoxy)phenyl]-2-pyridineethanol (2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3,4-tetrazol-1-yl)- 1-{5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl}propan-2-ol  Oteseconazole, also known as VT-1161, is a tetrazole antifungal agent potentially for the treatment of candidal vaginal infection. VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection. VT-1161 dosed once daily or …

Ibrexafungerp citrate

It’s only fair to share… Ibrexafungerp citrate アイブレキサフンジェルプクエン酸塩; Formula C44H67N5O4. C6H8O7 cas 1965291-08-0 free 1207753-03-4 Mol weight 922.1574 Brexafemme, fda approved 2021, 2021/6/1 Antifungal, Cell wall biosynthesis inhibitor, Treatment of invasive fungal infections due to Candida spp. or Aspergillus spp., vulvovaginal candidiasis SCY-078 citrate, MK-3118; SCY-078, WHO 10597 UNII-M4NU2SDX3E M4NU2SDX3E (1R,5S,6R,7R,10R,11R,14R,15S,20R,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7-[(2R)-3-methylbutan-2-yl]-20-(5-pyridin-4-yl-1,2,4-triazol-1-yl)-17-oxapentacyclo[13.3.3.01,14.02,11.05,10]henicos-2-ene-6-carboxylic acid;2-hydroxypropane-1,2,3-tricarboxylic acid Originator Merck & Co; SCYNEXIS Class Antifungals; Glycosides; …