It’s only fair to share… Motixafortide 4F-benzoyl-TN-14003 BKT-140 BKT140 BL-8040 Protein Chemical FormulaC97H144FN33O19S2 Protein Average Weight2159.6 Da UNIIDA9G065962CAS number664334-36-5 >Motixafortide sequence RRXCYXKKPYRXCR Motixafortide acetate 2639893-42-6 GMUZYOKQKWMETH-AQDOTSTFSA-N fda approved,9/8/2023, Aphexda мотиксафортид [Russian] موتيكسافورتيد [Arabic] 莫替福肽 [Chinese] Motixafortide is a peptide inhibitor of CXCR4 used to mobilize hematopoietic stem cells prior to collection and autologous transplantation in multiple myeloma patients. …
Evobrutinib
It’s only fair to share… Evobrutinib 429.5 g/mol,C25H27N5O2 Evobrutinib 1415823-73-2 Evobrutinib [INN] 1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)piperidin-1-yl)prop-2-en-1-one MSC2364447C MSC2364447C M-2951 MSC-2364447C ZA45457L1K 1-[4-[[[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino]methyl]piperidin-1-yl]prop-2-en-1-one M2951 Evobrutinib is under investigation in clinical trial NCT03934502 (Effect of Meal Composition and Timing on Evobrutinib Bioavailability). Evobrutinib is an inhibitor of Bruton’s tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, evobrutinib inhibits the activity of …
Zuranolone
It’s only fair to share… Zuranolone CAS 1632051-40-1 Zurzuvae FDA APPROVED 8/4/2023, To treat postpartum depression Press Release WeightAverage: 409.574 Monoisotopic: 409.272927379Chemical FormulaC25H35N3O2 SAGE 217 SAGE-217 SAGE217 Zuranolone, sold under the brand name Zurzuvae, is a medication used for the treatment of postpartum depression.[1][2] It is taken by mouth.[1] The most common side effects include drowsiness, dizziness, diarrhea, fatigue, nasopharyngitis, and urinary tract infection.[1][2] An orally active inhibitory pregnane neurosteroid, zuranolone acts as a positive …
EIDD-2173, ATI-2173, Fosclevudine alafenamide
It’s only fair to share… EIDD-2173; also known as ATI-2173 Fosclevudine alafenamide Molecular Weight 529.45 Formula C22H29FN3O9P CAS No. 1951476-79-1 phase 2 Hepatitis B virus (HBV) is an infectious disease that targets the liver resulting in either an acute infection, with symptoms arising in 45 to 160 days, or a chronic infection, which 350 …
Palovarotene
It’s only fair to share… Palovarotene Sohonos CAS 410528-02-8 4-[(E)-2-[5,5,8,8-tetramethyl-3-(pyrazol-1-ylmethyl)-6,7-dihydronaphthalen-2-yl]ethenyl]benzoic acid FDA 8/16/2023 To reduce the volume of new heterotopic ossification in adults and pediatric patients (aged 8 years and older for females and 10 years and older for males) with fibrodysplasia ossificans progressiva RG-667 RO-3300074 Palovarotene, sold under the brand name Sohonos, is a medication used for the treatment …
Zavegepant
It’s only fair to share… Zavegepant ザベジェパント; 1337918-83-8 as HCl: 1414976-20-7 C36H46N8O3 BASE 638.8 g/mol BASE Vazegepant BMS-742413 BHV-3500 FDA APPR 3/9/2023Zavzpret N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxamide ZAVZPRET is indicated for the acute treatment of migraine with or without aura in adults. The recommended dose of ZAVZPRET is 10 mg given as a single spray in one nostril, as needed. The …
MAVORIXAFOR
It’s only fair to share… MAVORIXAFOR AMD 070 N1-(1H-BENZIMIDAZOL-2-YLMETHYL)-N1-((S)-5,6,7,8-TETRAHYDROQUINOLIN-8-YL)-BUTANE-1,4-DIAMINE Mavorixafor (AMD-070) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively. Molecular Weight 349.47 Appearance Solid Formula C21H27N5 CAS No. …
Amcenestrant (SAR 439859)
It’s only fair to share… Amcenestrant (SAR 439859) アムセネストラント Molecular Weight 554.48 Formula C31H30Cl2FNO3 CAS No. 2114339-57-8 6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid Amcenestrant 8-(2,4-dichlorophenyl)-9-(4-{[(3 S )-1-(3-fluoropropyl)pyrrolidin-3-yl]oxy}phenyl)-6,7-dihydro – 5H- Benzo[7]annulene-3-carboxylic acid 8-(2,4-Dichlorophenyl)-9-(4-{[(3 S )-1-(3-fluoropropyl)pyrrolidin-3-yl]oxy}phenyl)-6,7-dihydro-5 H -benzo [7]annulene-3-carboxylic acid C31H30Cl2FNO3 : 554.48 [ 2114339-57-8 ] _ _ _ _ _ _ Efficacy Antineoplastic, Selective estrogen receptor downregulator Comment Selective estrogen receptor downregulator (SERD) Treatment of breast cancer SAR439859 (compound 43d) is an orally active, nonsteroidal and selective estrogen receptor degrader …
SC-52458, FORASARTAN
It’s only fair to share… SC-52458, FORASARTAN Molecular FormulaC23H28N8 Average mass416.522 Da PHASE 2, PFIZER, HYPERTENSION 145216-43-9 [RN] 5-[(3,5-Dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(1H-tetrazol-5-yl)phenyl]pyridine 5-[(3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]pyridine форасартан [Russian] [INN], فوراسارتان[Arabic][INN], 福拉沙坦[Chinese][INN] 065F7WPT0B [DBID] 7415 [DBID] UNII-065F7WPT0B [DBID] SC 52458 [DBID] Type-1 angiotensin II receptor Forasartan, otherwise known as the compound SC-52458, is a nonpeptide angiotensin II receptor antagonist (ARB, AT1 receptor blocker).[2][3][4][5] Forasartan, a specific angiotensin II antagonist, is used alone or with …
Adagrasib
It’s only fair to share… Adagrasib Formula C32H35ClFN7O2 cas 2326521-71-3 Mol weight 604.1174 Antineoplastic Disease Non-small cell lung cancer 2022/12/12 FDA APPROVED, KRAZATI (Mirati Therapeutics) MRTX-849 MRTX849 KRAS G12C inhibitor MRTX849 Adagrasib, sold under the brand name Krazati, is an anticancer medication used to treat non-small cell lung cancer.[1][2] Adagrasib is an inhibitor of the RAS GTPase family.[1] It is taken by mouth.[1] It …