IMIPRIDONE

It’s only fair to share… IMIPRIDONE CAS No. : 1616632-77-9 Molecular Weight, 386.4964 Related CAS #: 41276-02-2 (TIC10 isomer)   1616632-77-9 (free base)   1638178-82-1 (HCl)   1777785-71-3 (HBr)   2007141-57-1 (2HBr) TIC 10, 0NC 201, OP 10 Synonym: ONC201; ONC 201; ONC-201; NSC350625; NSC-350625; NSC 350625; TIC10; TIC 10; TIC-10; TRAIL inducing compound 10; imipridone 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one 2,4,6,7,8,9-Hexahydro-4-((2-methylphenyl)methyl)-7-phenylmethyl)imidazo)(1,2-a)pyrido(3,4-e)pyrimidin-5(1H)-one ONC-201 Dihydrochloride C24H28Cl2N4O 459.4 UNII-53VG71J90J …

Tirzepatide

It’s only fair to share… YXEGTFTSDY SIXLDKIAQK AFVQWLIAGG PSSGAPPPS Tirzepatide チルゼパチド LY3298176, Formula C225H348N48O68 CAS 2023788-19-2 Mol weight 4813.4514 FDA APPROVED 2022/5/13, Mounjaro Class Antidiabetic agent GLP-1 receptor agonist Efficacy Antidiabetic, Gastric inhibitory polypeptide receptor agonist, Glucagon-like peptide 1 (GLP-1) receptor agonist   Disease Type 2 diabetes mellitus L-Serinamide, L-tyrosyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-2-methylalanyl-L-leucyl-L-α-aspartyl-L-lysyl-L-isoleucyl-L-alanyl-L-glutaminyl-N6-[(22S)-22,42-dicarboxy-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazadotetracont-1-yl]-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-alanylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl- Other Names L-Tyrosyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-2-methylalanyl-L-leucyl-L-α-aspartyl-L-lysyl-L-isoleucyl-L-alanyl-L-glutaminyl-N6-[(22S)-22,42-dicarboxy-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazadotetracont-1-yl]-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-alanylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serinamide Tirzepatide is an agonist of human …

CLOSANTEL

It’s only fair to share… CLOSANTEL Closantel 57808-65-8 N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide MW 663.1, C22H14Cl2I2N2O2   Closantel Sodium CAS NO. 61438-64-0 FORMULA C22H13Cl2I2N2O2.Na M. WT 685.06 Closantel CAS Registry Number: 57808-65-8 CAS Name: N-[5-Chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodobenzamide Manufacturers’ Codes: R-31520 Trademarks: Flukiver (Janssen); Seponver (Ethnor) Molecular Formula: C22H14Cl2I2N2O2, Molecular Weight: 663.07 Percent Composition: C 39.85%, H 2.13%, Cl 10.69%, I 38.28%, N 4.22%, O 4.83% Literature References: Salicylanilide derivative. Prepn: M. …

MONENSIN

It’s only fair to share… モネンシン; MONENSIN Elancoban [veterinary] (TN) Molecular FormulaC36H62O11 Average mass670.871 Da 1,6-dioxaspiro[4.5]decane-7-butanoic acid, 2-[(2S,2’R,3’S,5R,5’R)-2-ethyloctahydro-3′-methyl-5′-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2′-bifuran]-5-yl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-, (αS,βR,γS,2S,5R,7S,8R,9S)- 17090-79-8 [RN] 241-154-0 [EINECS] (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2’R,3’S,5R,5’R)-2-Ethyl-5′-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3′-methyloctahydro-2,2′-bifuran-5-yl}-9-hydroxy-2,8-di methyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid монензин[Russian] مونانسين[Arabic] 莫能星[Chinese] Antibiotic, Antifungal, Antiprotozoal Synonym(s): Monensin A sodium salt Empirical Formula (Hill Notation):C36H61NaO11 CAS Number:22373-78-0 Molecular Weight:692.85 Beilstein:4122200 Title: Monensin CAS Registry Number: 17090-79-8 CAS Name: 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-b-methoxy-a,g,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid Additional Names: monensic acid (obsolete) Manufacturers’ …

SIBUTRAMINE

It’s only fair to share…   SIBUTRAMINE Molecular FormulaC17H26ClN Average mass279.848 Da 1-(4-Chlorophenyl)-N,N-dimethyl-a-(2-methylpropyl)cyclobutane methanamine 1-[1-(4-Chlorophenyl)cyclobutyl]-N,N,3-trimethyl-1-butanamine 106650-56-0 [RN] 106650-56-0 (Sibutramine ); 125494-59-9 (Sibutramine HCl Monohydrate); 84485-00-7 (Sibutramine HCl); 6124 UNII:WV5EC51866, WV5EC51866 сибутрамин[Russian] سيبوترامين[Arabic] 西布曲明[Chinese] Drug Name:Sibutramine Hydrochloride Hydrate Research Code:BTS-54524 Trade Name:Meridia® MOA:Serotonin-norepinephrine reuptake inhibitor Indication:Obesity Status:Withdrawn Company:Abbott (Originator) Sibutramine hydrochloride monohydrate, KES-524, BTS-54524, Meridia, Reductil Sibutramine, formerly …

Olipudase alfa

It’s only fair to share…   HPLSPQGHPA RLHRIVPRLR DVFGWGNLTC PICKGLFTAI NLGLKKEPNV ARVGSVAIKL CNLLKIAPPA VCQSIVHLFE DDMVEVWRRS VLSPSEACGL LLGSTCGHWD IFSSWNISLP TVPKPPPKPP SPPAPGAPVS RILFLTDLHW DHDYLEGTDP DCADPLCCRR GSGLPPASRP GAGYWGEYSK CDLPLRTLES LLSGLGPAGP FDMVYWTGDI PAHDVWHQTR QDQLRALTTV TALVRKFLGP VPVYPAVGNH ESTPVNSFPP PFIEGNHSSR WLYEAMAKAW EPWLPAEALR TLRIGGFYAL SPYPGLRLIS LNMNFCSREN FWLLINSTDP AGQLQWLVGE LQAAEDRGDK VHIIGHIPPG HCLKSWSWNY YRIVARYENT LAAQFFGHTH VDEFEVFYDE ETLSRPLAVA FLAPSATTYI GLNPGYRVYQ IDGNYSGSSH VVLDHETYIL NLTQANIPGA IPHWQLLYRA RETYGLPNTL …

TOLVAPTAN

It’s only fair to share… TOLVAPTAN 的合成 N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide Formula C26H25ClN2O3  Mol. mass 448.941 g/mol 150683-30-0 CAS NO + form  331947-66-1 Rform OPC-41061 Otsuka…..innovator   UPDATE 2022 Tolvaptan sodium phosphate, Samtasu, トルバプタンリン酸エステルナトリウム 2022/3/28 JAPAN PPROVED Formula C26H24ClN2O6P. 2Na CAS Mol weight 572.8849 Tolvaptan sodium phosphate disodium;[(5R)-7-chloro-1-[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl] phosphate European Medicines Agency (EMA) Accepts Otsuka’s Marketing Authorisation Application …

Andexanet alfa

It’s only fair to share…   (heavy chain) IVGGQECKDG ECPWQALLIN EENEGFCGGT ILSEFYILTA AHCLYQAKRF KVRVGDRNTE QEEGGEAVHE VEVVIKHNRF TKETYDFDIA VLRLKTPITF RMNVAPACLP ERDWAESTLM TQKTGIVSGF GRTHEKGRQS TRLKMLEVPY VDRNSCKLSS SFIITQNMFC AGYDTKQEDA CQGDAGGPHV TRFKDTYFVT GIVSWGEGCA RKGKYGIYTK VTAFLKWIDR SMKTRGLPKA KSHAPEVITS SPLK (light chan) ANSFLFWNKY KDGDQCETSP CQNQGKCKDG LGEYTCTCLE GFEGKNCELF TRKLCSLDNG DCDQFCHEEQ NSVVCSCARG YTLADNGKAC IPTGPYPCGK QTLER (Disulfide bridge: H7-H12, H27-H43, H108-L98, H156-H170, H181-H209, L16-L27, …

Ferric derisomaltose

It’s only fair to share… Ferric derisomaltose WeightAverage: 562.297 Monoisotopic: 562.117975Chemical FormulaC18H34FeO16 Monover, JAPAN 2022, 2022/3/28 Monoferric (TN); Monover (TN) Anti-anemic, Hematinic, Supplement (iron) CAS 1345510-43-1 デルイソマルトース第二鉄 NS32 WHO 9712 UNII-AHU547PI9H Originator Company Pharmacosmos Active Companies Nippon Shinyaku Co Ltd; Pharmacosmos A/S; Wasserburger Arzneimittelwerk Gmbh; Zealand University Hospital iron(3+) (2S,3R,4R,5R)-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}hexane-1,2,3,4,5-pentol alpha-D-Glucan, (1-6)-, reduced, reaction products with iron …

Difamilast

It’s only fair to share… Difamilast PMDA Moizerto, JAPAN APPROVED 2021/9/27 ジファミラスト ディファミラスト; 地法米司特 N-({2-[4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl]-1,3- oxazol-4-yl}methyl)-2-ethoxybenzamide OPA-15406 Formula C23H24F2N2O5 CAS 937782-05-3 Mol weight 446.4439 MM 36; MM-36-Medimetriks-Pharmaceuticals; Moizerto; OPA-15406 Efficacy Anti-inflammatory, Phosphodiesterase IV inhibitor Comment Treatment of atopic dermatitis OriginatorOtsuka Pharmaceutical Development & Commercialization DeveloperMedimetriks Pharmaceuticals; Otsuka Pharmaceutical Development & Commercialization ClassBenzamides; Nonsteroidal anti-inflammatories; Oxazoles; Skin disorder …