DETOMIDINE

It’s only fair to share…   DETOMIDINE 1H-Imidazole, 4-[(2,3-dimethylphenyl)methyl]- 4-(2,3-Dimethylbenzyl)-1H-imidazole 5078 76631-46-4 [RN] 7N8K34P2XH Molecular FormulaC12H14N2 Average mass186.253 Da UNII-7N8K34P2XH детомидин ديتوميدين 地托咪定 Formal Name 5-[(2,3-dimethylphenyl)methyl]-1H-imidazole, monohydrochloride CAS Number 90038-01-0 Synonyms Domosedan MPV 253AII Molecular Formula C12H14N2 • HCl Formula Weight 222.7 Detomidine CAS Registry Number: 76631-46-4 CAS Name: 4-[(2,3-Dimethylphenyl)methyl]-1H-imidazole Additional Names: 4-(2¢,3¢-dimethylbenzyl)imidazole Molecular Formula: C12H14N2 Molecular Weight: 186.25 Percent Composition: C 77.38%, …

Fenfluramine Hydrochloride

It’s only fair to share… Fenfluramine DEA No. 1670 S 768 2020/12/18, FDA APPROVED, Fintepla Fenfluramine hydrochloride Formula C12H16F3N. HCl CAS 404-82-0 458-24-2 (FREE) Mol weight 267.7183 Antiobesity Efficacy Appetite suppressant   Disease Dravet syndrome (+-)-Fenfluramine chloride (+-)-Fenfluramine hydrochloride Racemic fenfluramine hydrochloride Fenfluramine hydrochloride [USAN] AHR 3002 EINECS 206-968-2 1-(m-Trifluoromethylphenyl)-2-(ethylamino)propane hydrochloride AHR-3002 Research Code:ZX-008 MOA:Serotonin agonist …

Fluvoxamine

It’s only fair to share… Fluvoxamine Molecular FormulaC15H21F3N2O2 Average mass318.335 Da 54739-18-3 (E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone O-(2-Aminoethyl)oxime 1-Pentanone, 5-methoxy-1-[4-(trifluoromethyl)phenyl]-, O-(2-aminoethyl)oxime, (1E)- 2-[({(1E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino)oxy]ethanamine 2-{[(E)-{5-Methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino]oxy}ethanamine 1-Pentanone, 5-methoxy-1-(4-(trifluoromethyl)phenyl)-, O-(2-aminoethyl)oxime, (E)- 3879 54739-18-3 [RN] 5583954 [Beilstein] 5-Methoxy-4′-(trifluoromethyl)valerophenone (E)-O-(2-aminoethyl)oxime A selective serotonin reuptake inhibitor that is used in the treatment of DEPRESSION and a variety of ANXIETY DISORDERS. Fluvoxamine, sold under the brand name Luvox among others, …

Evinacumab

It’s only fair to share… (Heavy chain) EVQLVESGGG VIQPGGSLRL SCAASGFTFD DYAMNWVRQG PGKGLEWVSA ISGDGGSTYY ADSVKGRFTI SRDNSKNSLY LQMNSLRAED TAFFYCAKDL RNTIFGVVIP DAFDIWGQGT MVTVSSASTK GPSVFPLAPC SRSTSESTAA LGCLVKDYFP EPVTVSWNSG ALTSGVHTFP AVLQSSGLYS LSSVVTVPSS SLGTKTYTCN VDHKPSNTKV DKRVESKYGP PCPPCPAPEF LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSQEDPEVQ FNWYVDGVEV HNAKTKPREE QFNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKGLPSSIEK TISKAKGQPR EPQVYTLPPS QEEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSRLTVDK SRWQEGNVFS CSVMHEALHN HYTQKSLSLS LGK (Light chain) …

Tozinameran, Pfizer–BioNTech COVID‑19 vaccine

It’s only fair to share… SEQUENCE 1gagaauaaac uaguauucuu cuggucccca cagacucaga gagaacccgc 51caccauguuc guguuccugg ugcugcugcc ucuggugucc agccagugug 101ugaaccugac caccagaaca cagcugccuc cagccuacac caacagcuuu 151accagaggcg uguacuaccc cgacaaggug uucagaucca gcgugcugca 201cucuacccag gaccuguucc ugccuuucuu cagcaacgug accugguucc 251acgccaucca cguguccggc accaauggca ccaagagauu cgacaacccc 301gugcugcccu ucaacgacgg gguguacuuu gccagcaccg agaaguccaa 351caucaucaga ggcuggaucu ucggcaccac acuggacagc aagacccaga 401gccugcugau cgugaacaac gccaccaacg uggucaucaa agugugcgag 451uuccaguucu gcaacgaccc cuuccugggc gucuacuacc …

NIROGACESTAT

It’s only fair to share… NIROGACESTAT (2S)-2-[[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]pentanamide 489.6 g/mol, C27H41F2N5O CAS 1290543-63-3 PF-03084014, 1290543-63-3, PF-3084014, 865773-15-5 QZ62892OFJ UNII:QZ62892OFJ UNII-QZ62892OFJ нирогацестат [Russian] [INN] نيروغاسيستات [Arabic] [INN] 尼罗司他 [Chinese] [INN] ニロガセスタット; orphan drug designation in June 2018 for the treatment of desmoid tumors, and with a fast track designation  Nirogacestat, also known as PF-03084014, is a potent and selective gamma secretase (GS) inhibitor with potential antitumor activity. PF-03084014 …

Umbralisib

It’s only fair to share… Umbralisib tosylate Formula C31H24F3N5O3. C7H8O3S Cas 1532533-72-4 FREE 1532533-67-7 Mol weight 743.7508 FDA APPR 2021/2/5 ウムブラリシブトシル酸塩; Treatment of cancer and B-cell related disorders Antineoplastic RP-5152; RP-5237; PI3K delta inhibitors (cancer), Rhizen/Incozen; PI3K delta inhibitors (B-cell lymphoma/hematological cancers), Incozen/Rhizen; TGR-1202; TG-1202; RV-1001; umbralisib tosylate; umbralisib; RP-5264; RP-5307; dual PI3Kdelta/CK1 inhibitor (cancer), TG Therapeutics; …

Amiodarone

It’s only fair to share… Amiodarone CAS : 1951-25-3  (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone 2-butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone; 2-butyl-3-[3,5-diiodo-4-(b-diethylaminoethoxy)benzoyl]benzofuran Molecular Formula: C25H29I2NO3 Molecular Weight: 645.31 Percent Composition: C 46.53%, H 4.53%, I 39.33%, N 2.17%, O 7.44% In December 1985, amiodarone was approved by the FDA for the treatment of arrhythmias.[6] This makes amiodarone one of the few drugs approved by …

TROFINETIDE

It’s only fair to share… Trofinetide Molecular FormulaC13H21N3O6 Average mass315.322 Da Tofinetide , NNZ-2566 10076 853400-76-7 [RN] glycyl-2-methyl-L-prolyl-L-glutamic acid H-Gly-PMe-Glu-OH L-Glutamic acid, glycyl-2-methyl-L-prolyl- UNII-Z2ME8F52QL Z2ME8F52QL трофинетид [Russian] [INN] تروفينيتيد [Arabic] [INN] 曲非奈肽 [Chinese] [INN] IUPAC Condensed H-Gly-aMePro-Glu-OH Sequence GXE HELM PEPTIDE1{G.[*C(=O)[C@@]1(CCCN1*)C |$_R2;;;;;;;;_R1;$|].E}$$$$ IUPAC glycyl-alpha-methyl-L-prolyl-L-glutamic acid An (1-3) IGF-1 analog with neuroprotective activity. OPTICAL ROT; -52.4 °   Conc: 0.19 g/100mL;  water ;  589.3 …

IMRECOXIB

It’s only fair to share…   Imrecoxib (Hengyang) CHINA 2012  osteoarthritis 2H-Pyrrol-2-one, 1,5-dihydro-3-(4-methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl- 3-(4-Methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl-1,5-dihydro-2H-pyrrol-2-one   395683-14-4 [RN] Imrecoxib was approved by China Food and Drug Administration (CFDA) on May 20, 2011. It was developed and marketed as 恒扬® by HengRui Pharmaceuticals. Imrecoxib is a selective COX-2 inhibitor indicated for treatment of osteoarthritis. 恒扬® is available as tablet for …