Omecamtiv mecarbil オメカムティブメカビル

It’s only fair to share… Omecamtiv mecarbil Molecular FormulaC20H24FN5O3 Average mass401.435 Da 4-[2-fluoro-3-[(6-methyl-3-pyridyl)carbamoylamino]benzyl]piperazine-1-carboxylic acid methyl ester AMG 423 AMG-423 CK1827452 CK-1827452; CK1827452 Cladribine [BAN] [INN] [JAN] [USAN] [Wiki] methyl 4-(2-fluoro-3-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate 1-Piperazinecarboxylic acid, 4-[[2-fluoro-3-[[[(6-methyl-3-pyridinyl)amino]carbonyl]amino]phenyl]methyl]-, methyl ester 2M19539ERK オメカムティブメカビル 873697-71-3 [RN] 9088 Methyl 4-(2-fluoro-3-{[(6-methyl-3-pyridinyl)carbamoyl]amino}benzyl)-1-piperazinecarboxylate NMR https://file.selleckchem.com/downloads/nmr/S262301-CK-1827452-NMR-Selleck.pdf In January 2019, Cytokinetics and licensees Amgen and Servier are developing oral modified- and immediate-release formulations of the cardiac …

K-8986

It’s only fair to share… K-8986 (Z)-but-2-enedioic acid;7-[3-[4-[[1-(2-ethoxyethyl)benzimidazol-2-yl]methyl]piperazin-1-yl]propoxy]-4H-1,4-benzothiazin-3-one cas 1335112-55-4 mono maleate cas 1335112-57-6  di maleate cas 219741-69-2 free form C27 H35 N5 O3 S . C4 H4 O4 2H-1,4-Benzothiazin-3(4H)-one, 7-[3-[4-[[1-(2-ethoxyethyl)-1H-benzimidazol-2-yl]methyl]-1-piperazinyl]propoxy]-, (2Z)-2-butenedioate (1:1) 7-[3-[4-[[1-(2-Ethoxyethyl)benzimidazol-2-yl]methyl]-1-piperazinyl]propoxy]-3,4-dihydro-2H-1,4-benzothiazin-3-one monomaleate KOWA CO., LTD. 福田 友昭 FUKUDA, Tomoaki; JP 纐纈 章泰 KOKETSU, Akiyasu; JP 金児 佳生 KANEKO, Yoshio; JP 芦川 由香 ASHIKAWA, Yuka; JP Mono maleate 1H NMR (396 MHz, DMSO-d6) δ 1.03 (t, J = …

Tagraxofusp タグラクソフスプ

It’s only fair to share… MGADDVVDSS KSFVMENFSS YHGTKPGYVD SIQKGIQKPK SGTQGNYDDD WKGFYSTDNK YDAAGYSVDN ENPLSGKAGG VVKVTYPGLT KVLALKVDNA ETIKKELGLS LTEPLMEQVG TEEFIKRFGD GASRVVLSLP FAEGSSSVEY INNWEQAKAL SVELEINFET RGKRGQDAMY EYMAQACAGN RVRRSVGSSL SCINLDWDVI RDKTKTKIES LKEHGPIKNK MSESPNKTVS EEKAKQYLEE FHQTALEHPE LSELKTVTGT NPVFAGANYA AWAVNVAQVI DSETADNLEK TTAALSILPG IGSVMGIADG AVHHNTEEIV AQSIALSSLM VAQAIPLVGE LVDIGFAAYN FVESIINLFQ VVHNSYNRPA YSPGHKTRPH MAPMTQTTSL KTSWVNCSNM IDEIITHLKQ PPLPLLDFNN LNGEDQDILM ENNLRRPNLE AFNRAVKSLQ NASAIESILK NLLPCLPLAT AAPTRHPIHI KDGDWNEFRR …

Ifetroban イフェトロバン

It’s only fair to share… Ifetroban イフェトロバン 3-[2-({(1S,2R,3S)-3-[4-(Pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]hept-2-yl}methyl)phenyl]propanoic acid Molecular FormulaC25H32N2O5 Average mass440.532 Da 143443-90-7; 3-[2-({(1S,2R,3S)-3-[4-(Pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]hept-2-yl}methyl)phenyl]propanoic acid Benzenepropanoic acid, 2-[[(1S,2R,3S)-3-[4-[(pentylamino)carbonyl]-2-oxazolyl]-7-oxabicyclo[2.2.1]hept-2-yl]methyl]- 3-[2-[[(1S,5S,6R)-5-[4-(pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]heptan-6-yl]methyl]phenyl]propanoic acid Benzenepropanoic acid, 2-((3-(4-((pentylamino)carbonyl)-2-oxazolyl)-7-oxabicyclo(2.2.1)hept-2-yl)methyl)-, (1S-(exo,exo))- BMS 180,291 BMS 180291-02 BMS180291 BMS 18029; BMS 180291; BMS 180291A; BMS-180291-02; Boxaban; CPI 211; Hepatoren; Portaban; Vasculan Ifetroban is a potent and selective thromboxane receptor antagonist.[1] Ifetroban has been used in …

Aceclofenac, ацеклофенак , أسيكلوفيناك , 醋氯芬酸 , アセクロフェナク

It’s only fair to share… Aceclofenac アセクロフェナク Molecular FormulaC16H13Cl2NO4 Average mass354.185 Da (2-{2-[(2,6-Dichlorophenyl)amino]phenyl}acetoxy)acetic acid [ACD/IUPAC Name] (2-{2-[(2,6-Dichlorphenyl)amino]phenyl}acetoxy)essigsäure [German] [ACD/IUPAC Name] 5608 89796-99-6 [RN] Aceclofenac [BAN] [INN] [JAN] [Wiki] acéclofénac [French] [INN] Aceclofenaco [Spanish] [INN] Aceclofenacum [Latin] [INN] Acide (2-{2-[(2,6-dichlorophényl)amino]phényl}acétoxy)acétique [French] [ACD/IUPAC Name] Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, carboxymethyl ester [ACD/Index Name] RPK779R03H ацеклофенак[Russian][INN] أسيكلوفيناك[Arabic][INN] 醋氯芬酸[Chinese][INN] [({2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid [2-(2,6-Dichloro-phenylamino)-phenyl]-acetic acid carboxymethyl ester Aceclofenac CAS Registry Number: 89796-99-6 CAS Name: 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester Additional Names: 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid; glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate …

Diclofenac Sodium

It’s only fair to share… Diclofenac Sodium 15307-79-6; Sodium diclofenac; Diclofenac sodium salt; Voltaren; Solaraze Molecular Formula: C14H10Cl2NNaO2 Molecular Weight: 318.129 g/mol Diclofenac, sold under the trade names Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout.[3] It is taken by mouth or applied to the skin.[3] Improvements in pain typically occur within …

Clotrimazole

It’s only fair to share… Clotrimazole Molecular FormulaC22H17ClN2 Average mass344.837 Da 1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole (9CI) 1-(o-Chloro-a,a-diphenylbenzyl)imidazole 1-[(2-Chlorophenyl)(diphenyl)methyl]-1H-imidazole 1-[(o-Chlorophenyl)diphenylmethyl]imidazole 1-[a-(2-Chlorophenyl)benzhydryl]imidazole 1H-Imidazole, 1-[(2-chlorophenyl)diphenylmethyl]- 1H-Imidazole, 1-[(2-chlorophenyl)-diphenylmethyl] 23593-75-1 [RN] 245-764-8 [EINECS] 2912 Bis-fenil-(2-clorofenil)-1-imidazolil-metano [Italian] Bisphenyl-(2-chlorphenyl)-1-imidazolyl-methan [German] Canesten [Trade name] Canifug [Trade name] Clotrimazole [BAN] [INN] [JAN] [USAN] [Wiki] Clotrimazolum [Latin] Empecid [Trade name] Fungicip [Trade name] G07GZ97H65 Gyne-Lotrimin [Trade name] Imidazole, 1- (o-chloro-α,α-diphenylbenzyl)- Lotrimin [Trade name] Mono-baycuten [Trade name] Mycelex [Trade name] Mycelex G [Trade name] Mycosporin [Trade name] Pedisafe [Trade name] …

SELETALISIB, селеталисиб , سيلستاليسيب , 司来利塞 ,

It’s only fair to share… SELETALISIB CAS 1362850-20-1 UCB-5857 , Plaque psoriasis,Sjoegren’s syndrome,Immunodeficiency disorders PHASE 3 UCB 23H14ClF3N6O , 482.85 Phosphatidylinositol 3 kinase delta (PI3Kδ) inhibitors 10023 1362850-20-1 [RN] N-{(1R)-1-[8-Chlor-2-(1-oxido-3-pyridinyl)-3-chinolinyl]-2,2,2-trifluorethyl}pyrido[3,2-d]pyrimidin-4-amine N—{(R)-1-[8-Chloro-2-(pyridin-3-yl)quinolin-3-yl]-2,2,2-trifluoroethyl}N-(1-oxypyrido-[3,2-d]pyrimidin-4-yl)amine Pyrido[3,2-d]pyrimidin-4-amine, N-[(1R)-1-[8-chloro-2-(1-oxido-3-pyridinyl)-3-quinolinyl]-2,2,2-trifluoroethyl]- 3-{8-chloro-3-[(1R)-2,2,2-trifluoro-1-({pyrido[3,2-d]pyrimidin-4-yl}amino)ethyl]quinolin-2-yl}pyridin-1-ium-1-olate селеталисиб [Russian] [INN] سيلستاليسيب [Arabic] [INN] 司来利塞 [Chinese] [INN] N-[(1R)-1-[8-chloro-2-(1-oxidopyridin-1-ium-3-yl)quinolin-3-yl]-2,2,2-trifluoroethyl]pyrido[3,2-d]pyrimidin-4-amine Seletalisib has been used in trials studying the treatment and basic science of Primary Sjogren’s Syndrome. Originator UCB Class Anti-inflammatories; Small molecules Mechanism …

PF-06650833

It’s only fair to share… PF-06650833 1-{[(2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide CAS 1817626-54-2 Chemical Formula: C18H20FN3O4 Molecular Weight: 361.3734 Originator Pfizer Class Anti-inflammatories; Antirheumatics Mechanism of Action Interleukin-1 receptor-associated kinase inhibitors Phase II Rheumatoid arthritis Phase I Lupus vulgaris 01 Aug 2018 Pfizer completes a phase II trial in Rheumatoid arthritis (Treatment-experienced) in USA, Ukraine, Taiwan, Serbia, Russia, Romania, Poland, Mexico, South Korea, Georgia, Bosnia-Herzegovina, …

PF 06650808

It’s only fair to share… . Picture credit….Bethany Halford PF 06650808 CAS 1822383-80-1 A biologic for cancer treatment (Pfizer Inc.) Originator Pfizer Class Antineoplastics Mechanism of Action Notch-3 receptor antagonists No development reported Solid tumours 24 Jun 2018 Biomarkers information updated 28 Apr 2018 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease) in USA (IV) 01 Jul 2017 Pfizer …