Category «Flow chemistry»

Tropylium salts as efficient organic Lewis acid catalysts for acetalization and transacetalization reactions in batch and flow

It’s only fair to share… Tropylium salts as efficient organic Lewis acid catalysts for acetalization and transacetalization reactions in batch and flow Green Chem., 2017, Advance Article DOI: 10.1039/C7GC01519D, Communication D. J. M. Lyons, R. D. Crocker, D. Enders, T. V. Nguyen Tropylium salts were reported as organic-Lewis acids to efficiently catalyze acetalization reactions in …

Flow synthesis of Meclinertant

It’s only fair to share… SR48692 (Meclinertant) Reminertant; SR 48692 CAS [146362-70-1] Molecular FormulaC32H31ClN4O5 Average mass587.065 SEE……https://newdrugapprovals.org/2014/12/31/meclinertant-sr48692/ 2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid Originatorsanofi-aventis ClassAnalgesics; Antineoplastics; Antipsychotics Mechanism of ActionNeurotensin antagonists Meclinertant (SR-48692) is a drug which acts as a selective, non-peptide antagonist at the neurotensin receptor NTS1, and was the first non-peptide antagonist developed for this receptor.[1][2] It …

Continuous Flow Stereoselective Synthesis of (S)-Warfarin

It’s only fair to share… Continuous Flow Stereoselective Synthesis of (S)-Warfarin The same catalytic packed-bed reactor was used for the preparation of (S)-warfarin 107 under continuous flow conditions (Scheme ).A solution of 4-OH-coumarin 104, benzalacetone105, and trifluoroacetic acid as a cocatalyst in dioxane was flowed into the reactor containing the polystyrene-supported 9-amino-epi-quinine 122. With a …

Diphenhydramine Hydrochloride, Use of Flow Synthesis

It’s only fair to share… Diphenhydramine Hydrochloride REGULAR SYNTHESIS FLOW SYNTHESIS   Diphenhydramine hydrochloride is the active pharmaceutical ingredient in several widely used medications (e.g., Benadryl, Zzzquil, Tylenol PM, Unisom), and its worldwide demand is higher than 100 tons/year. In 2013, Jamison and co-workers developed a continuous flow process for the synthesis of 3 minimizing waste …

Flow Chemistry in Industrial Scale Organic Synthesis, 17th Jan, 2017 from 9-5pm in Ramada Powai Hotel & Convention Centre, Mumbai, India.

It’s only fair to share… ABOUT COURSE https://selectbiosciences.com/trainingCoursesID.aspx?tc=FCTC17&pid=5024&conf=FCI17&se=india FCI 2017 http://selectbiosciences.com/conferences/index.aspx?conf=FCI17&se=india VENUE http://selectbiosciences.com/conferences/venue.aspx?pid=4870&conf=FCI17&se=india SELECTBIO is pleased to present the training course on Flow Chemistry in Industrial Scale Organic Synthesis, which is scheduled to be held on 17th January, 2017 from 9:00am to 5:00pm in Ramada Powai Hotel & Convention Centre, Mumbai, India. This course will …

Flow Chemistry Symposium + Workshop on 27-28th Aug’ 2016 at IISER – PUNE, Pune, India

It’s only fair to share… Flow Chemistry Society – India Chapter is assisting the proliferation of Process Intensification and Flow Chemistry across the country After  an  enthusiastic  response  at the  2nd FCS-India Symposium & Workshop held at IICT-Hyderabad  in June’16  with  27companies and 115 delegates attending,  we are happy to announce : The 3rd   2-day FLOW CHEMISTRY …