Category «Uncategorized»

Maribavir

It’s only fair to share…   Maribavir Molecular FormulaC15H19Cl2N3O4 Average mass376.235 Da FDA APROVED 11/23/2021, Livtencity 1263 W94, 1263W94 176161-24-3 [RN] 1H-Benzimidazol-2-amine, 5,6-dichloro-N-(1-methylethyl)-1-β-L-ribofuranosyl- UNII-PTB4X93HE1, марибавир , ماريبافير  ,马立巴韦 , BW-1263W94 Camvia, D04859, G1263, GW257406X 1263W94; BW-1263W94; GW-1263; GW-257406X; SHP-620; VP-41263 Company:GlaxoSmithKline (Originator) , Shire MOA:UL97 kinase inhibitor Indication:CMV prophylaxis To treat post-transplant cytomegalovirus (CMV) infection/disease that does not respond (with or without genetic mutations that cause resistance) to available antiviral …

AMOROLFINE

It’s only fair to share…   AMOROLFINE (2R,6S)-2,6-Dimethyl-4-{2-methyl-3-[4-(2-methyl-2-butanyl)phenyl]propyl}morpholine (2R,6S)-2,6-Dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine 78613-35-1 [RN] (±)-cis-2,6-Dimethyl-4-(2-methyl-3-(p-tert-pentylphenyl)propyl)morpholine Ro 14-4767-002 аморолфин , أمورولفين  ,阿莫罗芬  , Title: Amorolfine CAS Registry Number: 78613-35-1 CAS Name:cis-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine Additional Names:cis-4-[3-(4-tert-amylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine; (±)-cis-2,6-dimethyl-4-[2-methyl-3-(p-tert-pentylphenyl)propyl]morpholine Manufacturers’ Codes: Ro-14-4767/000 Molecular Formula: C21H35NO Molecular Weight: 317.51 Percent Composition: C 79.44%, H 11.11%, N 4.41%, O 5.04% Literature References: Antimycotic morpholine derivative; inhibits fungal ergosterol biosynthesis. Prepn (unspec stereochem): A. Pfiffner, K. …

Acetaminosalol

It’s only fair to share…   Acetaminosalol Molecular FormulaC15H13NO4 Average mass271.268 Da ацетаминосалол [Russian] [INN], أسيتامينوسالول [Arabic] [INN], 醋氨沙洛 [Chinese] [INN] (1E)-N-{4-[(2-Hydroxybenzoyl)oxy]phenyl}ethanimidic acid 118-57-0 [RN] 204-261-3 [EINECS] CAS Registry Number: 118-57-0 CAS Name: 2-Hydroxybenzoic acid 4-(acetylamino)phenyl ester Additional Names: p-acetamidophenyl salicylate; acetylaminophenyl salicylate; acetyl-p-aminosalol; p-acetylaminophenol salicylic acid ester; phenetsal Trademarks: Salophen (Bayer); Phenosal Molecular Formula: C15H13NO4 Molecular Weight: 271.27 Percent Composition: C 66.41%, H 4.83%, N 5.16%, O 23.59% Literature References: Prepn: Brewster, J. Am. …

LINZAGOLIX

It’s only fair to share… LINZAGOLIX CAS 935283-04-8 C22H15F3N2O7S Hormone Antagonists 3-[5-[(2,3-difluoro-6-methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl]-2,4-dioxo-1H-thieno[3,4-d]pyrimidine-5-carboxylic acid WHO 10711 Treatment of Endometriosis Pain and Uterine Myoma-Associated Heavy Menstrual Bleeding OriginatorKissei Pharmaceutical DeveloperKissei Pharmaceutical; ObsEva Class2 ring heterocyclic compounds; Antihormones; Antineoplastics; Carboxylic acids; Fluorinated hydrocarbons; Ketones; Pyrimidines; Small molecules; Thiophenes Mechanism of ActionLHRH receptor antagonists PreregistrationUterine leiomyoma Phase IIIEndometriosis Phase IIAdenomyosis …

Ropeginterferon alfa-2b

It’s only fair to share… PCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE (Disulfide bridge: 2-99, 30-139) Ropeginterferon alfa-2b AOP2014 CAS 1335098-50-4 UNII981TME683S FDA APPROVED, 2021/11/12, BESREMI PEPTIDE, Antineoplastic, Antiviral Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, …

SULCONAZOLE

It’s only fair to share…   SULCONAZOLE сульконазол , سولكونازول , 硫康唑 Molecular FormulaC18H15Cl3N2S Average mass397.749 Da 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]- [ACD/Index Name] 4332 5D9HAA5Q5S 61318-90-9 [RN] (±)-1-[2,4-Dichloro-b-[(p-chlorobenzyl)thio]phenethyl]imidazole 1-[2-[[(4-Chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole : Sulconazole CAS Registry Number: 61318-90-9 CAS Name: 1-[2-[[(4-Chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole Additional Names: (±)-1-[2,4-dichloro-b-[(p-chlorobenzyl)thio]phenethyl]imidazole Molecular Formula: C18H15Cl3N2S Molecular Weight: 397.75 Percent Composition: C 54.35%, H 3.80%, Cl 26.74%, N 7.04%, S 8.06% Literature References: Prepn: K. A. M. Walker, DE2541833; idem,US4055652 (1976, 1977 both to …

TNO 155

It’s only fair to share… TNO 155 2-Oxa-8-azaspiro[4.5]decan-4-amine, 8-[6-amino-5-[(2-amino-3-chloro-4-pyridinyl)thio]-2-pyrazinyl]-3-methyl-, (3S,4S)- (3S,4S)-8-[6-Amino-5-[(2-amino-3-chloro-4-pyridinyl)thio]-2-pyrazinyl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine (3S,4S)-8-(6-amino-5-((2-amino-3-chloropyridin-4-yl)thio)pyrazin-2-yl)-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine Molecular Weight 421.95 Formula C₁₈H₂₄ClN₇OS CAS No. 1801765-04-7   PTPN11 inhibitor TNO155 SHP2 inhibitor TNO155 TNO-155 TNO155 UNII-FPJWORQEGI   TNO155 is a potent selective and orally active allosteric inhibitor of wild-type SHP2 (IC50=0.011 µM). TNO155 has the potential for the study of RTK-dependent malignancies, especially …

CILENGITIDE

It’s only fair to share… IUPAC Condensed cyclo[Arg-Gly-Asp-D-Phe-N(Me)Val] HELM PEPTIDE1{R.G.D.[dF].[meV]}$PEPTIDE1,PEPTIDE1,5:R2-1:R1$$$ IUPAC cyclo[L-arginyl-glycyl-L-alpha-aspartyl-D-phenylalanyl-N-methyl-L-valyl]     CILENGITIDE Molecular FormulaC27H40N8O7 Average mass588.656 Da 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid 188968-51-6 [RN] 4EDF46E4GI 7823 циленгитид سيلانجيتيد 西仑吉肽 EMD 121974, EMD-121974, UNII-4EDF46E4GI 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid Cilengitide has been in phase III clinical trials by Merck Serono and NCI for the treatment of glioblastoma multiforme. However, this research has been …

Methotripremazine

It’s only fair to share… Methotripremazine 60-99-1  7104-38-3 (maleate), 1236-99-3 HCl) CL 36467 CL 39743 N05AA02 RP 7044 RP-7044 SK&F 5116 XP-03 XP03 Product Ingredients INGREDIENT UNII CAS INCHI KEY Methotrimeprazine hydrochloride 42BB1Y2586 1236-99-3 ODLGFPIWRAEFAN-PFEQFJNWSA-N Methotrimeprazine maleate 5KN5Y9V01K 7104-38-3 IFLZPECPTYCEBR-VIEYUMQNSA-N Methotrimeprazine CAS Registry Number: 60-99-1 CAS Name: (bR)-2-Methoxy-N,N,b-trimethyl-10H-phenothiazine-10-propanamine Additional Names: (-)-10-(3-dimethylamino-2-methylpropyl)-2-methoxyphenothiazine; levomepromazine; 2-methoxytrimeprazine; levomeprazine Manufacturers’ Codes: RP-7044 Trademarks: Sinogan-Debil; Tisercin (EGYT); Neozine …

Methiomeprazine

It’s only fair to share… Methiomeprazine N,N,2-trimethyl-3-(2-methylsulfanylphenothiazin-10-yl)propan-1-amine CAS 7009-43-0 Molecular Formula, C19-H24-N2-S2, Molecular Weight, 344.5446, 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-2-(methylthio)-, (±)- Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-2-(methylthio)-, (±)- (8CI) N,N,β-Trimethyl-2-(methylthio)-10H-phenothiazine-10-propanamine (±)-10-(3-Dimethylamino-2-methylpropyl)-2-(methylthio)phenothiazine 10584-RP 2-Methylthio-10-(2-methyl-3-dimethylaminopropyl)phenothiazine Methiomeprazine SKF 6270 (+-)-10-(3-Dimethylamino-2-methylpropyl)-2-(methylthio)phenothiazine Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-2-(methylthio)-, (+-)- 10584 RP EINECS 230-285-9 Methiomeprazinum Methiomeprazinum [INN-Latin] Metiomeprazina Metiomeprazina [INN-Spanish] RP 10584 SKF 6270 UNII-X2R9QTF0OL Methiomeprazine hydrochloride 14056-64-5 Methiomeprazine maleate 101037-46-1 join me on Linkedin …