TEGAFUR

It’s only fair to share… Tegafur CAS 17902-23-7 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)- Molecular Weight,200.17, MF C8 H9 F N2 O3 172-173 °C Miyashita, Osamu; Chemical & Pharmaceutical Bulletin 1981, 29(11), PG 3181-90 Uracil, 5-fluoro-1-(tetrahydro-2-furyl)- Utefos Venoterpine WY1559000 YR0450000 5-fluoro-1-tetrahydrofuran-2-ylpyrimidine-2,4(1H,3H)-dione Carzonal N1-(2′-Furanidyl)-5-fluorouracil Synonyms:Ftorafur ATC:L01BC03 EINECS:241-846-2 LD50:800 mg/kg (M, i.v.); 775 mg/kg (M, p.o.); 685 mg/kg (R, i.v.); 930 …

FDA approves first generic Strattera (atomoxetine) for the treatment of ADHD

It’s only fair to share… FDA approves first generic Strattera (atomoxetine) for the treatment of ADHD 05/30/2017 04:49 PM EDT The U.S. Food and Drug Administration today approved the first generic versions of Strattera (atomoxetine) to treat attention-deficit/hyperactivity disorder (ADHD) in pediatric and adult patients. 05/30/2017 The U.S. Food and Drug Administration today approved the …

FDA approves first drug Actemra (tocilizumab) to specifically treat giant cell arteritis

It’s only fair to share… FDA approves first drug to specifically treat giant cell arteritis 05/22/2017 The U.S. Food and Drug Administration today expanded the approved use of subcutaneous Actemra (tocilizumab) to treat adults with giant cell arteritis. This new indication provides the first FDA-approved therapy, specific to this type of vasculitis. May 22, 2017 …

Linrodostat BMS 986205

It’s only fair to share… cas 2221034-29-1 Linrodostat (2R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide Linrodostat mesylate Linrodostat [USAN] UNII-OS7OBU191R OS7OBU191R Linrodostat mesylate [USAN] BMS-986205-04 2221034-29-1 Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-alpha- methyl-, (alphaR,1alpha,4alpha)-, methanesulfonate (1:1) Linrodostat; (2R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide; Linrodostat mesylate; Linrodostat [USAN]; UNII-OS7OBU191R; OS7OBU191R   BMS 986205 (2R)-N-(4-Chlorophenyl)-2-[cis-4-(6-fluoro-4-quinolinyl)cyclohexyl]propanamide Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methyl-, cis- Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methyl-, cis-(αR)- (i?)-N-(4-chlorophenyl)-2- c 5-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide CAS: 1923833-60-6 Phase III Head and neck cancer; Malignant melanoma BMS-986205, ONO-7701,  …

Metopimazine

It’s only fair to share… Metopimazine RP-9965, EXP-999, NG-101 l-(3-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]propyl)-4-piperidinecarboxamide CAS 14008-44-7 MF C22 H27 N3 O3 S2 MW 445.60 4-Piperidinecarboxamide, 1-[3-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]propyl]- Isonipecotamide, 1-[3-[2-(methylsulfonyl)phenothiazin-10-yl]propyl]- (7CI,8CI) 1-[3-[2-(Methylsulfonyl)-10H-phenothiazin-10-yl]propyl]-4-piperidinecarboxamide 1-[3-[2-(Methylsulfonyl)phenothiazin-10-yl]propyl]-4-piperidinecarboxamide 1-[3-[2-(Methylsulfonyl)phenothiazin-10-yl]propyl]isonipecotamide 2-Methylsulfonyl-10-[3-(4-carbamoylpiperidino)propyl]phenothiazine EXP 999 Metopimazine RP 9965 Vogalene metopimazine (gastroparesis), Neurogastrx Sanofi (Originator) Teva Treatment of Nausea and Vomiting, APPROVED Dopamine D3 receptor antagonist; Dopamine D2 receptor antagonist Gastroprokinetic Metopimazine …

2-pyrazolin-5-one

It’s only fair to share… 137-45-1 cas 3-Pyrazolin-5-one (8CI) Pyrazol-3(or 5)-ol (6CI,7CI) 1,2-Dihydro-3H-pyrazol-3-one 1,2-Dihydropyrazol-3-one 1H-Pyrazol-3-ol 1H-Pyrazol-5-ol 3-Hydroxypyrazole 3-Pyrazoline-5-one 3-Pyrazolone 4-Pyrazolin-3-one NSC 520837 Pyrazol-3-ol Pyrazol-5-ol   Compound 1: Under stirring, to a solution of 5.81 g (50 mmol) of methyl (2E)-3-methoxyacrylate in methanol (5 mL) was hydrazine hydrate (2.75 g, 55 mmol) added and the mixture …

3-(2-(Benzoylamino)ethyl)-1-phenyl-1H-pyrazol-5-yl benzoate

It’s only fair to share… 3-(2-(Benzoylamino)ethyl)-1-phenyl-1H-pyrazol-5-yl benzoate (14). Benzoyl chloride (0.230 mL, 2 mmol) was added to a stirred suspension of amine 6c (276 mg, 1 mmol) in a mixture of anhydrous dichloromethane (10 mL) and 4-methylmorpholine (0.66 mL, 6 mmol) and the mixture was stirred at r.t. for 12 h. Volatile component were evaporated …

FDA approves drug to treat ALS, Radicava (Edaravone) , эдаравон, إيدارافون , 依达拉奉 ,ラジカット,

It’s only fair to share… FDA approves drug to treat ALS 05/05/2017 The U.S. Food and Drug Administration today approved Radicava (edaravone) to treat patients with amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig’s disease. May 5, 2017 Release The U.S. Food and Drug Administration today approved Radicava (edaravone) to treat patients with …