It’s only fair to share… Crenolanib Molecular FormulaC26H29N5O2 Average mass443.541 Da 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine 1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine 1-[2-[5-[(3-methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine 4-Piperidinamine, 1-[2-[5-[(3-methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]- 670220-88-9 [RN] 9459 UNII-LQF7I567TQ креноланиб كرينولانيب 克拉尼布 CP-868,596-26 or AR-868,596-26 Crenolanib besylate CAS#: 670220-93-6 (besylate) Chemical Formula: C32H35N5O5SMolecular Weight: 601.72 Crenolanib besylate (CP-868,596-26 or AR-868,596-26, 4-piperidinamine, 1-[2-[5-[(3-Methyl-3-oxetanyl) methoxy]-1H-benzimidazol-1-yl]- 8-quinolinyl]-, monobenzenesulfonate) is an investigational inhibitor being developed by AROG Pharmaceuticals, LLC. The …
Ganaxolone
It’s only fair to share… Ganaxolone Molecular FormulaC22H36O2 Average mass332.520 Da (3a,5a)-3-Hydroxy-3-methylpregnan-20-one (3α,5α)-3-Hydroxy-3-methylpregnan-20-one 38398-32-2 [RN] 3α-hydroxy-3β-methyl-5α-pregnan-20-one 7476 CCD-1042 FDA APPROVED 3/18/2022, Ztalmy To treat seizures in cyclin-dependent kinase-like 5 deficiency disorder Ganaxolone, sold under the brand name Ztalmy, is a medication used to treat seizures associated with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD).[1][2] Ganaxolone was approved for medical use in …
Ciltacabtagene autoleucel
It’s only fair to share… Ciltacabtagene autoleucel FDA APPROVED, 2022/2/28, Carvykti Treatment of multiple myeloma JNJ-68284528 LCAR-B38M CAR-T cells Ciltacabtagene autoleucel is a BCMA-directed CAR T-cell therapy used in the treatment of relapsed or refractory multiple myeloma in previously treated patients. U.S. FDA Approves CARVYKTI™ (ciltacabtagene autoleucel), Janssen’s First Cell Therapy, a BCMA-Directed CAR-T …
PACRITINIB
It’s only fair to share… Pacritinib パクリチニブ; Formula C28H32N4O3 CAS 937272-79-2 Mol weight 472.5787 UPDATE FDA APPROVED 2/28/2022, Vonjo To treat intermediate or high-risk primary or secondary myelofibrosis in adults with low platelets A Jak2 inhibitor potentially for the treatment of acute myeloid Leukemia and myelofibrosis. UNII-G22N65IL3O пакритиниб باكريتينيب 帕瑞替尼 ONX-0803; SB-1518 CAS No. …
TRIAMCINOLONE
It’s only fair to share… TRIAMCINOLONE Molecular FormulaC21H27FO6 Average mass394.434 Da (11β,16α)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione (8S,9R,10S,11S,13S,14S,16R,17S)-9-Fluor-11,16,17-trihydroxy-17-(hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-on (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(hydroxyacétyl)-10,13-diméthyl-6,7,8,9,10,11,12,13,14,15,16,17-dodécahydro-3H-cyclopenta[a]phénanthrén-3-one (8S,9R,10S,11S,13S,14S,16R,17S)-9-Fluoro-17-glycoloyl-11,16,17-trihydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one 124-94-7 [RN] 16a-Hydroxy-9a-fluoroprednisolone 1ZK20VI6TY 204-718-7 [EINECS] 755 9a-Fluoro-16a-hydroxyprednisolone TU3850000 トリアムシノロン[Japanese] 去炎松[Chinese] Triamcinolone CAS Registry Number: 124-94-7 CAS Name: (11b, 16a)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione Additional Names: D1-9a-fluoro-16a-hydroxyhydrocortisone; 9a-fluoro-16a-hydroxyprednisolone; D1-16a-hydroxy-9a-fluorohydrocortisone; 16a-hydroxy-9a-fluoroprednisolone Manufacturers’ Codes: CL-19823 Trademarks: Aristocort (Lederle); Kenacort (BMS); Ledercort (tabl.) (Lederle); Omcilon (BMS); Tricortale (Bergamon); Volon (BMS) Molecular Formula: C21H27FO6, Molecular Weight: 394.43 Percent …
Ensitrelvir
It’s only fair to share… Ensitrelvir S-217622, S 217622, Xocova, SHIONOGI, 6-[(6-chloro-2-methylindazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[(2,4,5-trifluorophenyl)methyl]-1,3,5-triazine-2,4-dione CAS 2647530-73-0 C22H17ClF3N9O2 531.9 Synonyms BDBM513874 bioRxiv20220126.477782, S-217622 Ensitrelvir fumarate CAS No. : 2757470-18-9 C22 H17 Cl F3 N9 O2 . C4 H4 O4 1,3,5-Triazine-2,4(1H,3H)-dione, 6-[(6-chloro-2-methyl-2H-indazol-5-yl)imino]dihydro-3-[(1-methyl-1H-1,2,4-triazol-3-yl)methyl]-1-[(2,4,5-trifluorophenyl)methyl]-, (6E)-, (2E)-2-butenedioate (1:1) Formula: C26H21ClF3N9O6 M. Wt. : 647.95 A Phase 1 study of S-217622 in healthy adult participants (jRCT2031210202) Japan Registry of Clinical Trials Web …
RADOTINIB
It’s only fair to share… RADOTINIB Molecular FormulaC27H21F3N8O Average mass530.504 Da 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(2-pyrazinyl)-2-pyrimidinyl]amino}benzamide 4-methyl-N-[3-(4-methylimidazole-l-yl)-5-trifluoromethyl-phenyl] – 3-(4-pyrazine-2-yl-pyrimidine-2-yl amino)benzamide 9242 926037-48-1 [RN] 926037-48-1 (Radotinib); 926037-85-6 (Radotinib 2HCl); Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(2-pyrazinyl)-2-pyrimidinyl]amino]- I284LJY110, IY5511 UNII-I284LJY110 радотиниб رادوتينيب 雷度替尼 MOA：Bcr-Abl tyrosine kinase inhibitor Indication：Chronic myeloid leukemia (CML ) Company：IL-Yang (Originator) IY-5511; IY-5511A3001 Approval Date Approval Type Trade Name Indication Dosage Form Strength Company Review Classification …
Cyclobenzaprine
It’s only fair to share… Cyclobenzaprine Molecular FormulaC20H21N Average mass275.387 Da MK-130 TNX-102 1-(3-Dimethylaminopropylidene)-2,3:6,7-dibenzo-4-suberene 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl- [ACD/Index Name] 206-145-8 [EINECS] 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine 303-53-7 [RN] 5-(3-Dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene циклобензаприн [Russian] [INN] سيكلوبنزابرين [Arabic] [INN] 环苯扎林 [Chinese] [INN] Cyclobenzaprine, CAS Registry Number: 303-53-7 CAS Name: 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine Additional Names: N,N-dimethyl-5H-dibenzo[a,d]cyclohepten-D5,g-propylamine; 5-(3-dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene; 1-(3-dimethylaminopropylidene)-2,3:6,7-dibenzo-4-suberene; proheptatriene Manufacturers’ Codes: MK-130; Ro-4-1577; RP-9715 Molecular Formula: C20H21N, Molecular Weight: 275.39 Percent Composition: C 87.23%, H 7.69%, N 5.09% Literature References: Prepn: GB 858187 (1961 to Hoffmann-La Roche); Villani et al., J. …
Pyritinol
It’s only fair to share… Pyritinol Molecular FormulaC16H20N2O4S2 Average mass368.471 Da 1098-97-1 [RN] 1308 214-150-1 [EINECS] 233-178-5 [EINECS] 3,3′-[Dithiobis(methylene)]bis[5-hydroxy-6-methyl-4-pyridinemethanol] 4-Pyridinemethanol, 3,3′-[dithiobis(methylene)]bis[5-hydroxy-6-methyl- пиритинол [Russian] [INN] بيريتينول [Arabic] [INN] 吡硫醇 [Chinese] [INN] Pyritinol, CAS Registry Number: 1098-97-1 CAS Name: 3,3¢-[Dithiobis(methylene)]bis[5-hydroxy-6-methyl-4-pyridinemethanol] Additional Names: bis(4-hydroxymethyl-5-hydroxy-6-methyl-3-pyridylmethyl) disulfide; bis[(3-hydroxy-4-hydroxymethyl-2-methyl-5-pyridyl)methyl] disulfide; dipyridoxolyldisulfide; pyridoxine-5-disulfide; pyrithioxin Molecular Formula: C16H20N2O4S2, Molecular Weight: 368.47 Percent Composition: C 52.15%, H 5.47%, N 7.60%, O 17.37%, S 17.40% Literature References: Prepn: Zima, Schorre, US 3010966 (1961 to E. Merck); Iwanami et …
Liranaftate
It’s only fair to share… Liranaftate リラナフタート 88678-31-3 (6-Methoxy-2-pyridinyl)methylcarbamothioic Acid O-(5,6,7,8-Tetrahydro-2-naphthalenyl) Ester O-(5,6,7,8-Tetrahydronaphthalen-2-yl) (6-methoxypyridin-2-yl)methylcarbamothioate Zefnart;Piritetrate;M-732 лиранафтат ليرانافتات 利拉萘酯 Formula C18H20N2O2S CAS 88678-31-3 Mol weight 328.4286 Efficacy Antifungal, Ergosterol biosynthesis inhibitor Comment Thiocarbamate Liranaftate (trade name Zefnart) is a topical antifungal drug.[1] It is used as a 2% cream used to treat tinea pedis (athlete’s foot), tinea corporis (ringworm), and tinea cruris (jock itch).[2] It was approved for use …