It’s only fair to share… Deuruxolitinib C17H18N6, 314.422 Fda approved Leqselvi, 7/25/2024, To treat severe alopecia areata C-21543, CTP 543, CTP-543, CTP543 (3r)-3-(2,2,3,3,4,4,5,5-d8)cyclopentyl-3-(4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazol-1-yl)propanenitrile 1h-pyrazole-1-propanenitrile, .beta.-(cyclopentyl-2,2,3,3,4,4,5,5-d8)-4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-, (.beta.r)-D8-ruxolitinib Ingredient UNII CAS InChI Key Deuruxolitinib phosphate 8VJ43S4LCM 2147706-60-1 JFMWPOCYMYGEDM-NTVOUFPTSA-N unii 0CA0VSF91Y Deuruxolitinib, sold under the brand name Leqselvi, is a medication used for the treatment of alopecia areata.[1] It is a Janus …
Tag «approvals 2024»
Vorasidenib
It’s only fair to share… Vorasidenib6-(6-chloropyridin-2-yl)-N2,N4-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine CAS 1644545-52-7, C14H13ClF6N6, 414.74 FDA APPROVED, 8/6/2024, Voranigo, To treat Grade 2 astrocytoma or oligodendroglioma UNII 789Q85GA8P Ingredient UNII CAS InChI Key Vorasidenib citrate X478M962XG 2316810-02-1 YOUTVRFNJAAFNS-DLVAHKFUSA-N Vorasidenib citrate anhydrous W4XG3EQK7B 2316810-00-9 OCEHQNOYRLHJCI-WPRTUUMNSA-N Vorasidenib, sold under the brand name Voranigo, is an anti-cancer medication used for the treatment of certain forms of glioma.[1][2] Vorasidenib …
Palopegteriparatide
It’s only fair to share… Palopegteriparatide Yorvipath , FDA 2024, 8/9/2024, To treat hypoparathyroidism Palopegteriparatide Palopegteriparatide is a human parathyroid hormone analogue corresponding to amino acid residues 1 – 34 of human parathyroid hormone, to which a methoxy polyethylene glycol (molecular weight: ca. 43,000) is bound via a cleavable linker (pegylation site: S1). Palopegteriparatide is …
Seladelpar
It’s only fair to share… Seladelpar cas 851528-79-5 C21H23F3O5S, 444.47 Fda approved 8/14/2024, To treat primary biliary cholangitis (PBC), Livdelzi Ingredient UNII CAS InChI Key Seladelpar lysine N1429130KR 928821-40-3 WTKSWPYGZDCUNQ-JZXFCXSPSA-N (+)-MBX-8025 MBX 8025 MBX-8025 MBX8025 RWJ-800025 ((4-(((2R)-2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)THIO)-2-METHYLPHENYL)OXY)ACETIC ACID (4-(((2R)-2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)SULFANYL)-2-METHYLPHENOXY)ACETIC ACID PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR) AGONIST,ANTIHYPERLIPIDAEMIC (R)-2-(4-((2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)-THIO)-2-METHYLPHENOXY)ACETIC ACID ACETIC ACID, (4-(((2R)-2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)THIO)-2-METHYLPHENOXY)- ACETIC ACID, (4-(((2R)-2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)THIO)-2-METHYLPHENOXY)- ((4-(((2R)-2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)THIO)-2-METHYLPHENYL)OXY)ACETIC ACID ACETIC ACID, 2-(4-(((2R)-2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)THIO)-2-METHYLPHENOXY)- Seladelpar …
lazertinib
It’s only fair to share… lazertinib CAS 1903008-80-9 554.655, C30H34N8O3 2-PROPENAMIDE, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)-2-PYRIMIDINYL)AMINO)-4-METHOXY-2-(4-MORPHOLINYL)PHENYL)- N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE C-18112003-G GNS 1480 GNS-1480 GNS1480 JNJ-73841937-AAA YH 25448 YH-25448 YH25448 FDA APPROVED 8/19/2024 To treat non-small cell lung cancer, Lazcluze Ingredient UNII CAS InChI Key Lazertinib mesylate monohydrate WUT449BEG5 2411549-88-5 ZJPNGZUERUYZEG-UHFFFAOYSA-N Lazertinib is an oral, third-generation, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor …
ACT-132577, Aprocitentan
It’s only fair to share… ACT-132577, Aprocitentan, N-Despropyl-macitentan 1103522-45-7 546.19, C16H14Br2N6O4S WHO 10552 3/19/2024 FDA APPROVED, To treat hypertension, Tryvio N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]aminosulfonamide Aprocitentan, sold under the brand name Tryvio, is a medication used to treat hypertension (high blood pressure).[1] It is developed by Idorsia.[2] It is taken by mouth.[1] Aprocitentan is a dual endothelin-1 antagonist that targets both endothelin A and endothelin B receptors.[3][4] Aprocitentan was approved for medical use in …
Cefepime
It’s only fair to share… Cefepime 88040-23-7 INGREDIENT UNII CAS INCHI KEY Cefepime hydrochloride I8X1O0607P 123171-59-5 LRAJHPGSGBRUJN-OMIVUECESA-N Cefepime CAS Registry Number: 88040-23-7 CAS Name: 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methylpyrrolidinium inner salt Additional Names: 1-[[(6R,7R)-7-[2-(2-amino-4-thiazolyl)glyoxylamido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methylpyrrolidinium hydroxide inner salt 72-(Z)-2-(O-methyloxime); 7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-(1-methylpyrrolidinio)methyl-3-cephem-4-carboxylate Manufacturers’ Codes: BMY-28142 Molecular Formula: C19H24N6O5S2 Molecular Weight: 480.56 Percent Composition: C 47.49%, H 5.03%, N 17.49%, O 16.65%, S 13.34% Literature References: Semisynthetic, fourth generation cephalosporin …
Berdazimer
It’s only fair to share… Berdazimer 1846565-00-1 CAS NA SALT, 1846565-00-1 FDA APPROVE 1 /5/2024, To treat molluscum contagiosum Drug Trials Snapshot NVN-1000 free acid NVN1000 free acid Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with silicic acid (h4sio4) tetra-et ester, hydroxy-terminated Berdazimer sodium, sold under the brand name Zelsuvmi, is a medication used for the treatment for molluscum contagiosum.[1] Berdazimer sodium is a nitric …
Ceftobiprole
It’s only fair to share… C20H22N8O6S2 534.57 209467-52-7 (6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(N-hydroxyimino)acetamido]-8-oxo-3-{[(3E,3’R)-2-oxo-[1,3′-bipyrrolidin]-3-ylidene]methyl}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid BAL-9141 BAL-9141-000 BAL-9141000 BAL9141-000 RO 63-9141 RO-63-9141 RO-639141 ceftobiprole medocaril sodium Ro-655788 BAL-5788-001 Molecular Weight 712.64 Formula C26H25N8NaO11S2 CAS No. 252188-71-9 Appearance Solid Color Off-white to light yellow SMILES O=C(C(N(C1=O)[C@@](SC2)([H])[C@@H]1NC(/C(C3=NSC(N)=N3)=N\O)=O)=C2/C=C(CCN4[C@@](CC5)([H])CN5C(OCC(OC6=O)=C(O6)C)=O)/C4=O)O[Na] fda approved 4/3/2024, To treat certain bloodstream infections, bacterial skin and associated tissue infections, and community-acquired bacterial …
Danicopan
It’s only fair to share… Danicopan USFDA 3/29/2024, To treat extravascular hemolysis with paroxysmal nocturnal hemoglobinuria, Voydeya C26H23BrFN7O3 580.418 1903768-17-1 (2S,4R)-1-[2-[3-acetyl-5-(2-methylpyrimidin-5-yl)indazol-1-yl]acetyl]-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine-2-carboxamide ACH 0144471 ACH-4471 ACH0144471 ALXN 2040 ALXN-2040 ALXN2040 Danicopan, sold under the brand name Voydeya, is a medication used for the treatment of paroxysmal nocturnal hemoglobinuria.[2] It is a complement inhibitor which reversibly binds to factor D to prevent alternative pathway-mediated hemolysis and …