Tag «APROVALS 2023»

Rezafungin

It’s only fair to share… Rezafungin CAS 1396640-59-7 WeightAverage: 1226.411Monoisotopic: 1225.602719729 Chemical FormulaC63H85N8O17 FDA APPROVED 3/22/2023, Rezzayo, To treat candidemia and invasive candidiasisDrug Trials Snapshot 2-[[(3S,6S,9S,11R,15S,18S,20R,21R,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,25-trihydroxy-3,15-bis[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-[[4-[4-(4-pentoxyphenyl)phenyl]benzoyl]amino]-1,4,7,13,16,22-hexazatricyclo[22.3.0.09,13]heptacosan-21-yl]oxy]ethyl-trimethylazanium Rezafungin, sold under the brand name Rezzayo (by Melinta Therapeutics), is a medication used for the treatment of invasive candidiasis.[2] It is an echinocandin antifungal[1][4] that acts as a fungal β-glucan synthase inhibitor.[5] Rezafungin was approved for medical use in …