Tag «Ascentage Pharma»

Olverembatinib

It’s only fair to share… Olverembatinib WeightAverage: 532.571Monoisotopic: 532.219844002, Chemical FormulaC29H27F3N6O 1421783-64-3 Molecular Weight 724.77 Formula C31H35F3N6O7S2 Olverembatinib (GZD824) dimesylate is a potent and orally active pan-Bcr-Abl inhibitor. Olverembatinib dimesylate potently inhibits a broad spectrum of Bcr-Abl mutants. Olverembatinib dimesylate strongly inhibits native Bcr-Abl and Bcr-AblT315I with IC50s of 0.34 nM and 0.68 nM, respectively. Olverembatinib dimesylate has antitumor activity. Olverembatinib (dimesylate) is …