Tag «Atigliflozin»

 Atigliflozin

It’s only fair to share…   Atigliflozin CAS 647834-15-9 Chemical Formula: C18H22O7S Exact Mass: 382.1086 Molecular Weight: 382.43 AVE 2268; AVE-2268; AVE2268; Y0H7UPE4WJ (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-((2-(4-methoxybenzyl)thiophen-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol Atigliflozin (AVE-2268) is an orally active and selective SGLT-2 inhibitor, with IC50s of 10 nM and 8.2 μM for hSGLT-2 and hSGLT-1) respectively. Atigliflozin can lower the blood glucose and improve the impaired oral glucose tolerance. …