Tag «BMS 986115»

Varegacestat

It’s only fair to share… Varegacestat CAS 1584647-27-7 MF C26H25F7N4O3 MW574.5 (2R,3S)-N1-[(3S)-5-(3-fluorophenyl)-9-methyl-2-oxo-2,3-dihydro-1H1,4-benzodiazepin-3-yl]-2,3-bis(3,3,3-trifluoropropyl)butanediamide (2R,3S)-N1-((3S)-5-(3-FLUOROPHENYL)-2,3-DIHYDRO-9-METHYL-2-OXO-1H-1,4-BENZODIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPHENYL)BUTANEDIAMIDE(2R,3S)-N1-((3S)-5-(3-FLUOROPHENYL)-9-METHYL-2-OXO-2,3-DIHYDRO-1H-1,4-BENZODIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPHENYL)BUTANEDIAMIDEgamma-secretase inhibitor, antineoplastic, AL102, BMS 986115, LSK1L593UU, AL 102 BMS-986115 has been used in trials studying the treatment of Various Advanced Cancer. Varegacestat is an orally bioavailable, gamma secretase (GS) and pan-Notch inhibitor, with potential antineoplastic activity. Upon administration, varegacestat binds to GS …