It’s only fair to share… Donafenib CAS 1130115-44-4, CM-4307, Zepsun, 41XGO0VS1U 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-(trideuteriomethyl)pyridine-2-carboxamide CM-4307 is under investigation in clinical trial NCT03602495 (Donafenib in 131I-Refractory Differentiated Thyroid Cancer). Donafenib, sold under the brand name Zepsun, is a pharmaceutical drug for the treatment of cancer. In China, donafenib is approved for the treatment of unresectable hepatocellular carcinoma in patients who have …
Tag «CHINA 2021»
Olverembatinib
It’s only fair to share… Olverembatinib WeightAverage: 532.571Monoisotopic: 532.219844002, Chemical FormulaC29H27F3N6O 1421783-64-3 Molecular Weight 724.77 Formula C31H35F3N6O7S2 Olverembatinib (GZD824) dimesylate is a potent and orally active pan-Bcr-Abl inhibitor. Olverembatinib dimesylate potently inhibits a broad spectrum of Bcr-Abl mutants. Olverembatinib dimesylate strongly inhibits native Bcr-Abl and Bcr-AblT315I with IC50s of 0.34 nM and 0.68 nM, respectively. Olverembatinib dimesylate has antitumor activity. Olverembatinib (dimesylate) is …
Chiglitazar
It’s only fair to share… Chiglitazar CAS 743438-45-1 Ingredient UNII CAS InChI Key Chiglitazar sodium, (S)- YN12H6OCV6 2390374-10-2 RMVIEXHXRDCWBT-UCRKPPETSA-M Chiglitazar was developed by Chipscreen Biosciences and was approved in China for improving glycemic control in adultpatients with type2 diabetes in October2021. Chiglitazar (trade name Bilessglu) is a drug for the treatment of type 2 diabetes.[1] It is a peroxisome proliferator-activated …
Hetrombopag Olamine
It’s only fair to share… Hetrombopag Olamine, RAFUTROMBOPAG OLAMINE 2-aminoethanol;5-[2-hydroxy-3-[[5-methyl-3-oxo-2-(5,6,7,8-tetrahydronaphthalen-2-yl)-1H-pyrazol-4-yl]diazenyl]phenyl]furan-2-carboxylic acid (Z)-5-(2-Hydroxy-3-(2- (3-methyl-5-oxo-1-(5,6,7,8-tetrahydronaphthalen- 2-yl)-1H-pyrazol-4(5H)-ylidene)hydrazinyl)phenyl) furan-2-carboxylic acid diethanolamine CAS 1257792-42-9 1257792-41-8 (free acid) 1257792-41-8 (ethanolamine) 1257792-42-9 (olamine) Jiangsu Hengrui Pharmaceutical, was approved in China in June 2021 for treatment of adult patients with chronic primary immune thrombocytopenia (ITP) and severe aplastic anemia who have not responded well to …
Contezolid
It’s only fair to share… Contezolid WeightAverage: 408.337Monoisotopic: 408.104539468 Chemical FormulaC18H15F3N4O4 Shanghai MicuRx Pharmaceutical Co. Ltd Contezolid was approved for use by the National Medical Products Administration (NMPA) of China in 2021 Contezolid (trade name Youxitai) is an antibiotic of the oxazolidinone class.[1][2] It is effective against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Streptococcus pyogenes, Streptococcus agalactiae, and other bacteria.[3] In 2021, it was approved by the National Medical …