Tag «COVID-19»

Tozinameran, Pfizer–BioNTech COVID‑19 vaccine

It’s only fair to share… SEQUENCE 1gagaauaaac uaguauucuu cuggucccca cagacucaga gagaacccgc 51caccauguuc guguuccugg ugcugcugcc ucuggugucc agccagugug 101ugaaccugac caccagaaca cagcugccuc cagccuacac caacagcuuu 151accagaggcg uguacuaccc cgacaaggug uucagaucca gcgugcugca 201cucuacccag gaccuguucc ugccuuucuu cagcaacgug accugguucc 251acgccaucca cguguccggc accaauggca ccaagagauu cgacaacccc 301gugcugcccu ucaacgacgg gguguacuuu gccagcaccg agaaguccaa 351caucaucaga ggcuggaucu ucggcaccac acuggacagc aagacccaga 401gccugcugau cgugaacaac gccaccaacg uggucaucaa agugugcgag 451uuccaguucu gcaacgaccc cuuccugggc gucuacuacc …

Molnupiravir, EIDD 2801

It’s only fair to share…   EIDD 2801, Molnupiravir Molecular Formula: C13H19N3O7 Molecular Weight: 329.31 g/mol   CAS 2349386-89-4 [(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate UNII YA84KI1VEW Molnupiravir (development codes MK-4482 and EIDD-2801) is an experimental antiviral drug which is orally active (can be taken orally) and was developed for the treatment of influenza. It is a prodrug of the synthetic nucleoside derivative N4-hydroxycytidine, and exerts its antiviral action through introduction …

AZITHROMYCIN

It’s only fair to share… AZITHROMYCIN C38H72N2O12, 748.9845 アジスロマイシン; CAS: 83905-01-5 PubChem: 51091811 ChEBI: 2955 ChEMBL: CHEMBL529 DrugBank: DB00207 PDB-CCD: ZIT[PDBj] LigandBox: D07486 NIKKAJI: J134.080H CAS Registry Number: 83905-01-5 CAS Name: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one Additional Names: N-methyl-11-aza-10-deoxo-10-dihydroerythromycin A; 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A Molecular Formula: C38H72N2O12 Molecular Weight: 748.98 Percent Composition: C 60.94%, H 9.69%, N 3.74%, O 25.63% Literature References: Semi-synthetic macrolide antibiotic; related to erythromycin …

Camostat Mesilate, カモスタットメシル酸塩 日局収載

It’s only fair to share… Camostat Molecular FormulaC20H22N4O5 Average mass398.413 Da 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic Acid 2-(Dimethylamino)-2-oxoethyl Ester 4-{2-[2-(Dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate 59721-28-7 [RN] Benzeneacetic acid, 4-[[4-[(aminoiminomethyl)amino]benzoyl]oxy]-, 2-(dimethylamino)-2-oxoethyl ester Camostat Mesilate カモスタットメシル酸塩 日局収載 Trypsin-like protease inhibitor CAS 59721-29-8 C20H22N4O5.CH4O3S 494.52 MP 194, methanol, diethyl ether, Chemical and Pharmaceutical Bulletin, 2005, vol. 53, 8, pg. 893 – 898 カモスタットメシル酸塩 日局収載 Camostat Mesilate Dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate monomethanesulfonate C20H22N4O5▪CH4O3S : 494.52 [59721-29-8] Launched – 1985, in Japan …

Remdesivir, レムデシビル , ремдесивир , ريمديسيفير , 瑞德西韦 ,

It’s only fair to share…   Remdesivir Formula C27H35N6O8P CAS 1809249-37-3 Mol weight 602.576 レムデシビル UNII:3QKI37EEHE ремдесивир [Russian] [INN] ريمديسيفير [Arabic] [INN] 瑞德西韦 [Chinese] [INN] 2-Ethylbutyl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydro-2-furanyl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name) L-Alanine, N-((S)-hydroxyphenoxyphosphinyl)-, 2-ethylbutyl ester, 6-ester with 2-C-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-D-altrononitrile 2-Ethylbutyl (2S)-2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 2-Ethylbutyl (2S)-2-[[(S)-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate 2-Ethylbutyl (2S)-2-[[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate 2-Ethylbutyl N-[(S)-[2-C-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-D-altrononitril-6-O-yl]phenoxyphosphoryl]-L-alaninate GS 5734 L-Alanine, N-[(S)-hydroxyphenoxyphosphinyl)-, 2-ethylbutyl ester,6-ester with 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile GS-5734 Treatment of viral infections Phase III, clinical trials for the treatment …