Tag «EDP-938»

Zelicapavir

It’s only fair to share… Zelicapavir, Enanta Pharmaceuticals Alternative Names: EDP-938; EP 023938 cas 2070852-76-3 RSV-IN-7549.5 g/mol, C27H22F3N7O3 UNII U4OI721DMD (3S)-3-[[5-[3-morpholin-4-yl-5-(trifluoromethyl)pyridin-2-yl]-1,3,4-oxadiazol-2-yl]amino]-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one SYN New England Journal of Medicine (2022), 386(7), 655-666  WO2022157327 WO2018152413 WO2019067864  WO2017015449  PATENT WO2018152413 https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2018152413&_cid=P20-M0V26A-30323-1 Step 5 : (<Sf)-3-((5-(3-morpholino-5-(trifluoromethyl)pyridin-2-yl)-1.3.4-oxadiazol-2- To a mixture of (5)-2-(3-morpholino-5-(trifluoromethyl)picolinoyl)-N-2-oxo-5-phenyl-2,3-dihydro-lH-benzo[e] [l,4]diazepin-3-yl)hydrazine-l-carboxamide (1.4 kg, 1 eq.) in DCM (11.2 L) in a …