Tag «Histone deacetylase inhibitor»

Imofinostat

It’s only fair to share… Imofinostat CAS 1338320-94-7 MF C17H16N2O4S MW 344.4 g/mol (2E)-3-[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]-N-hydroxyprop2-enamidehistone deacetylase inhibitor, antineoplastic, ABT-301, MPT0E028, ABT 301, MPT0E 028, T65L58FI65 Imofinostat (also known as ABT-301 or MPT0E028) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor primarily being developed as an innovative precision oncology treatment. Developed by companies like AnBogen Therapeutics and …

Tucidinostat, Chidamide

It’s only fair to share…   Tucidinostat, Chidamide ツシジノスタット 2021/6/23 PMDA JAPAN APPROVED, Hiyasta Formula C22H19FN4O2 CAS 1616493-44-7 Mol weight 390.4103 Antineoplastic, Histone deacetylase inhibitor Chidamide (Epidaza) is a histone deacetylase inhibitor (HDI) developed in China.[1] It was also known as HBI-8000.[2] It is a benzamide HDI and inhibits Class I HDAC1, HDAC2, HDAC3, as well as Class IIb HDAC10.[3] Chidamide is approved by the Chinese FDA for …