Tag «Immunosuppressant»

Laporolimus

It’s only fair to share… Laporolimus Rapamycin, 42-cyclohexanecarboxylate CAS 1504576-27-5 MF C58H89NO14 MW 1024.3 g/mol [(1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl] cyclohexanecarboxylate (1R,2R,4S)-4-{(2R)-2-[(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-10,21-dimethoxy6,8,12,14,20,26-hexamethyl-1,5,11,28,29-pentaoxo1,4,5,6,9,10,11,12,13,14,21,22,23,24,25,26,27,28,29,31,32,33,34,34a-tetracosahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontin-3-yl]propyl}-2-methoxycyclohexylcyclohexanecarboxylateimmunosuppressant, CRC-015, CRC 015, F5041W3RVA, Rapamycin, 42-cyclohexanecarboxylate Laporolimus is an experimental immunosuppressant compound that acts as an mTOR (mechanistic target of rapamycin) pathway inhibitor. It is chemically classified as a macrolide derivative and is also known by its chemical …

EVEROLIMUS

It’s only fair to share… Everolimus 159351-69-6 [RN] 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydr oxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-, (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,26R,27R,34aS)- 23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-, (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)- 42-O-(2-Hydroxyethyl)rapamycin Synonyms:RAD-001, SDZ-RAD, Afinitor ATC:L04AA18 Use:immunosuppressant Chemical name:42-O-(2-hydroxyethyl)rapamycin Formula:C53H83NO14 MW:958.24 g/mol CAS-RN:159351-69-6 Everolimus CAS Registry Number: 159351-69-6 CAS Name: 42-O-(2-Hydroxyethyl)rapamycin Additional Names: 40-O-(2-hydroxyethyl)rapamycin Manufacturers’ Codes: RAD-001; SDZ RAD Trademarks: Certican (Novartis) Molecular Formula: C53H83NO14 Molecular Weight: 958.22 Percent Composition: C 66.43%, H 8.73%, N 1.46%, O 23.38% Literature References: Macrolide immunosuppressant; …