It’s only fair to share… Pimitespib TAS 116 CAS 1260533-36-5 Antineoplastic, Hsp 90 inhibitor 3-ethyl-4-[4-[4-(1-methylpyrazol-4-yl)imidazol-1-yl]-3-propan-2-ylpyrazolo[3,4-b]pyridin-1-yl]benzamide Pimitespib (TAS-116) is an oral bioavailable, ATP-competitive, highly specific HSP90α/HSP90β inhibitor (Kis of 34.7 nM and 21.3 nM, respectively) without inhibiting other HSP90 family proteins such as GRP94. Pimitespib demonstrates less ocular toxicity. Formula C25H26N8O CAS 1260533-36-5 Mol weight 454.5269 JAPAN APPROVED 2022/6/20, ピミテスピブ Jeselhy …