Tag «KO 2806»

Darlifarnib

It’s only fair to share… Darlifarnib CAS 2939824-30-1 MF C29H20N6O MW 468.51 14-amino-14-(3-methylimidazol-4-yl)-7-oxa-19-azapentacyclo[13.6.2.12,6.19,13.018,22]pentacosa-1(22),2(25),3,5,9,11,13(24),15(23),16,18,20-undecaene-10,20-dicarbonitrile farnesyl transferase inhibitor, antineoplastic, KO-2806, KO 2806, T206317 Darlifarnib (KO-2806) is an investigational, orally active next-generation farnesyl transferase inhibitor (FTI) being developed by Kura Oncology to treat solid tumors, such as clear cell renal cell carcinoma (ccRCC). It inhibits the enzyme farnesyl transferase, blocking KRAS and …