It’s only fair to share… Nedometinib CAS 2252314-46-6 NFX-179, K5T4I78IYZ Molecular Weight 470.24 Formula C17H16FIN4O3 2-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethoxy)-1-methylpyrrolo[2,3-b]pyridine-3-carboxamide Nedometinib (NFX-179) is a specific MEK1 inhibitor with an IC50 of 135 nM. Nedometinib inhibits p-ERK, MAPK. Nedometinib exerts anticancer activity against squamous cell carcinoma. Nedometinib can be used for research in dermatosis, neurofibromatosis. Nedometinib is a topical gel formulation composed of an inhibitor of mitogen-activated protein …