Tag «OPC-41061»

TOLVAPTAN

It’s only fair to share… TOLVAPTAN 的合成 N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide Formula C26H25ClN2O3  Mol. mass 448.941 g/mol 150683-30-0 CAS NO + form  331947-66-1 Rform OPC-41061 Otsuka…..innovator   UPDATE 2022 Tolvaptan sodium phosphate, Samtasu, トルバプタンリン酸エステルナトリウム 2022/3/28 JAPAN PPROVED Formula C26H24ClN2O6P. 2Na CAS Mol weight 572.8849 Tolvaptan sodium phosphate disodium;[(5R)-7-chloro-1-[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl] phosphate European Medicines Agency (EMA) Accepts Otsuka’s Marketing Authorisation Application …