It’s only fair to share… Fidaxomicin (C52H74Cl2O18, Mr = 1058.0 g/mol) Launched – 2011 MERCK, Clostridium difficile-associated diarrhea CUBIST ….INNOVATOR OPT-80 PAR-101 Also tiacumicin B or lipiarmycin A3, A bacterial RNA polymerase inhibitor as macrocyclic antibiotic used to treat clostridium difficile-associated diarrhea (CDAD). SYNTHESIS REFERENCES US 4918174 WO 2006085838 J ANTIBIOTICS 1987, 40, PG …