Tag «PF-04457845»

Redafamdastat

It’s only fair to share… Redafamdastat cas 1020315-31-4, PF 04457845 JZP-150; JZP150; PF-04457845; PF-4457845; PF04457845; PF4457845, Q7119045 WeightAverage: 455.441Monoisotopic: 455.156909393 Chemical FormulaC23H20F3N5O2   Redafamdastat (INNTooltip International Nonproprietary Name; developmental code names JZP-150, PF-04457845) is an inhibitor of the enzyme fatty acid amide hydrolase (FAAH), with an IC50Tooltip half-maximal inhibitory concentration of 7.2 nM, and both analgesic and anti-inflammatory effects in animal studies comparable to those of the cyclooxygenase inhibitor naproxen.[1] It was being developed by Jazz …