It’s only fair to share… SOVESUDIL PHP-201; AMA 0076, C23O3R93BM CAS 1333400-14-8 Molecular Weight 407.44 Formula C23H22FN3O3 Sovesudil (PHP-201) is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor with IC50s of 3.7 and 2.3 nM for ROCK-I and ROCK-II, respectively. Sovesudil lowers intraocular pressure (IOP) without inducing hyperemia. SCHEME PATENTS Bioorganic & Medicinal Chemistry Letters (2013), 23(23), …