Tag «Riselcaftor»

Riselcaftor

It’s only fair to share… Riselcaftor CAS 2799652-36-9 MF C29H28N2O5S MW 516.61 (2R,4R)-2-(2-methoxy-5-methylphenyl)-N-(2-methylquinoline-5-sulfonyl)-4-phenyloxolane-2-carboxamide (2R,4R)-2-(2-methoxy-5-methylphenyl)-N-(2-methylquinolin-5-yl)sulfonyl-4-phenyloxolane-2-carboxamidecystic fibrosis transmembrane regulator (CFTR)protein modulator, 726GWJ6KQQ Riselcaftor (Example 33) is a CFTR modulator, with an EC50 of 20.1 nM in human bronchial epithelial cells. Riselcaftor can be used for research of cystic fibrosis. SYN US20220211692 https://patentscope.wipo.int/search/en/detail.jsf?docId=US367940046&_cid=P11-MIH63N-23616-1 Example 33 (2R,4R)-2-(2-methoxy-5-methylphenyl)-N-(2-methylquinoline-5-sulfonyl)-4-phenyloxolane-2-carboxamide       The enantiomers of Example 32D …