It’s only fair to share… RP 12146, EX-A7910 cas 2732869-64-4 4-[[5-[(3R)-3-hydroxy-3-methyl-2-oxoindol-1-yl]pyridin-3-yl]methyl]-2H-phthalazin-1-one M.Wt 398.422 Formula C23H18N4O3 RP12146 (RP12146) is a novel, selective, and potent small molecule inhibitor of PARP1/2 with IC50 of 0.6/0.5 nM, with several fold selectivity over other isoforms. SCHEME Ref WO2021220120 Rhizen Pharmaceuticals AG WO2022215034 Rhizen Pharmaceuticals AG; Incozen Therapeutics Pvt. Ltd. RP-12146 …