Tag «RRx-001»

Nibrozetone

It’s only fair to share… Nibrozetone CAS 925206-65-1 MF C5H6BrN3O5 MW268.02 g/mol 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one 2-Bromo-1-(3,3-dinitroazetidin-1-yl)ethanone 2-BROMO-1-(3,3-DINITROAZETIDIN-1-YL)ETHAN-1-ONE anti-inflammatory, RRx-001, RRx 001, ABDNAZ Nibrozetone is an investigational new drug that is being evaluated by EpicentRx for the treatment of oral mucositis in head and neck cancer patients. It is a small molecule that combines direct inhibition of the NLRP3 inflammasome, induction of NRF2, and release of nitric oxide under hypoxic conditions.[1][2] It has received Fast Track designation from …