Tag «SR48692»

Flow synthesis of Meclinertant

It’s only fair to share… SR48692 (Meclinertant) Reminertant; SR 48692 CAS [146362-70-1] Molecular FormulaC32H31ClN4O5 Average mass587.065 SEE……https://newdrugapprovals.org/2014/12/31/meclinertant-sr48692/ 2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid Originatorsanofi-aventis ClassAnalgesics; Antineoplastics; Antipsychotics Mechanism of ActionNeurotensin antagonists Meclinertant (SR-48692) is a drug which acts as a selective, non-peptide antagonist at the neurotensin receptor NTS1, and was the first non-peptide antagonist developed for this receptor.[1][2] It …