Tag «treatment of pancreatic cancer»

NASTORAZEPIDE

It’s only fair to share…   Nastorazepide (Z-360) CAS: 209219-38-5 Chemical Formula: C29H36N4O5 Molecular Weight: 520.61994 UNII-R22TMY97SG; 209219-38-5; Phase II, treatment of pancreatic cancer. (R)-3-(3-(5-cyclohexyl-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)ureido)benzoic acid Nastorazepide, also known as Z-360, is a selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation …