Tag «Tryvio»

ACT-132577, Aprocitentan

It’s only fair to share…   ACT-132577, Aprocitentan, N-Despropyl-macitentan 1103522-45-7 546.19, C16H14Br2N6O4S WHO 10552 3/19/2024 FDA APPROVED, To treat hypertension, Tryvio N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]aminosulfonamide Aprocitentan, sold under the brand name Tryvio, is a medication used to treat hypertension (high blood pressure).[1] It is developed by Idorsia.[2] It is taken by mouth.[1] Aprocitentan is a dual endothelin-1 antagonist that targets both endothelin A and endothelin B receptors.[3][4] Aprocitentan was approved for medical use in …