Tag «tyrosine kinase inhibitor»

Lunbotinib

It’s only fair to share… Lunbotinib CAS 2479961-46-9 MF C28H28FN11 MW537.6 g/mol 2-[6-(6-{[6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl]methyl}-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl]-6-methyl-N-(5-methyl1H-pyrazol-3-yl)pyrimidin-4-aminetyrosine kinase inhibitor, antineoplastic, KL3T9ZU6HQ Lunbotinib is an orally bioavailable selective inhibitor of the proto-oncogene receptor tyrosine kinase rearranged during transfection (RET), with potential antineoplastic activity. Upon oral administration, lunbotinib selectively binds to various RET fusions and mutations, including solvent front resistance mutations, and inhibits the …