It’s only fair to share… Abaloparatide BA058 BIM-44058 UNII-AVK0I6HY2U BA058; BIM-44058; CAS 247062-33-5 MW 3960.5896, MF C174 H300 N56 O49 абалопаратид [Russian] [INN] أبالوباراتيد [Arabic] [INN] 巴罗旁肽 [Chinese] [INN] NAME………C2.29-methyl(22-L-glutamic acid(F>E),23-L-leucine(F>L),25-L-glutamic acid(H>E),26-L-lysine(H>K),28-L-leucine(I>L),30-L-lysine(E>K),31-L-leucine(I>L))human parathyroid hormone-related protein-(1-34)-proteinamide L-Alaninamide, L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-alpha-aspartyl-L-lysylglycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-alpha-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-lysyl-L-leucyl-L-leucyl-2-methylalanyl-L-lysyl-L-leucyl-L-histidyl-L-threonyl- L-Alaninamide, L-alanyl-L-valyl-L-seryl-L-α-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-α-aspartyl-L-lysylglycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-α-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-α-glutamyl-L-leucyl-L-leucyl-L-α-glutamyl-L-lysyl-L-leucyl-L-leucyl-2-methylalanyl-L-lysyl-L-leucyl-L-histidyl-L-threonyl- C2.29-methyl(22-L-glutamic acid(F>E),23-L-leucine(F>L),25-L-glutamic acid(H>E),26-L-lysine(H>K),28-L-leucine(I>L),30-L-lysine(E>K),31-L-leucine(I>L))human parathyroid hormone-related protein-(1-34)-proteinamide Biologic Depiction IUPAC Condensed H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2 Sequence AVSEHQLLHDKGKSIQDLRRRELLEKLLXKLHTA HELM PEPTIDE1{A.V.S.E.H.Q.L.L.H.D.K.G.K.S.I.Q.D.L.R.R.R.E.L.L.E.K.L.L.[Aib].K.L.H.T.A.[am]}$$$$ IUPAC (N-(L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-alpha-aspartyl-L-lysyl-glycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-alpha-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-lysyl-L-leucyl-L-leucyl)-2-aminoisobutyryl)-L-lysyl-L-leucyl-L-histidyl-L-threonyl-L-alaninamide Tymlos FDA 4/28/2017 To treat osteoporosis …
Category «peptide»
ELAMIPRETIDE
It’s only fair to share… Elamipretide H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH2 D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide (2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide CAS 736992-21-5 Chemical Formula: C32H49N9O5 Molecular Weight: 639.8 A free radical scavenger and antioxidant that localizes in the inner mitochondrial membrane. Mitochondrial Protective Agent to Improve Cell Viability Elamipretide bendavia UNII-87GWG91S09 736992-21-5 MTP 131 RX 31 SS 31 87GWG91S09 L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl- SS-31 peptide Arg-Dmt-Lys-Phe-NH2 D-Arg-Dmt-Lys-Phe-NH2 SS31 peptide …
RAPASTINEL рапастинел , راباستينيل , 雷帕替奈
It’s only fair to share… RAPASTINEL Molecular Formula C18H31N5O6 Average mass 413.469 Da L-threonyl-L-prolyl-L-prolyl-L-threoninamide (2S)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]pyrrolidine-2-carboxamide 117928-94-6 [RN] L-Threoninamide, L-threonyl-L-prolyl-L-prolyl- рапастинел [Russian] راباستينيل [Arabic] 雷帕替奈 [Chinese] (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide UNII-6A1X56B95E; 117928-94-6; 6A1X56B95E (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide [117928-94-6] GLYX-13 trifluoroacetate GLYX-13;GLYX13;GLYX 13;Thr-Pro-Pro-Thr-NH2 L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate MFCD20527320 Thr-Pro-Pro-Thr-NH2 trifluoroacetate TPPT-amide trifluoroacetate UNII:6A1X56B95E BV-102; GLYX13, GLYX-13, in phase 3 clinical trials Originator Northwestern University Developer Allergan; Naurex Class Amides; Antidepressants; Neuropsychotherapeutics; Oligopeptides; Small molecules Mechanism of …
The greening of peptide synthesis
It’s only fair to share… The greening of peptide synthesis Stefan B. Lawrenson,a Roy Arava and Michael North*a *Corresponding authors aGreen Chemistry Centre of Excellence, Department of Chemistry, University of York, York, UK E-mail: Michael.north@york.ac.uk Abstract The synthesis of peptides by amide bond formation between suitably protected amino acids is a fundamental part of …