It’s only fair to share… Preparation of (S)-5-Fluoro-3-methylisobenzofuran-1(3H)-one (6) To a ………………. Purity 99.9%, ee > 99.9%. 1H NMR (400 MHz, CDCl3): δ 7.88 (dd, J = 4.8, 8.4 Hz, 1 H), 7.21 (ddd, J = 2.0, 8.4, 8.8 Hz, 1 H), 7.12 (dd, J = 2.0, 8.8 Hz, 1 H), 5.53 (q, J = 6.4 Hz, 1 H), 1.63 (d, J = 6.4 Hz, 3 …
Category «spectroscopy»
syn-3,5-Dihydroxy Hexanoate
It’s only fair to share… pure 8 (2.4 g, HPLC purity, 92%). [α]D25 = −41.3 (c = 1.0, CHCl3), >99.5% de.(8g, 9) 1H NMR (CDCl3, 400 MHz), δ/ppm: 1.47 (s, 9H), 1.71–1.75 (m, 2H), 2.42–2.44 (m, 2H), 2.54–2.56 (m, 2H), 3.71 (brs, 2H), 4.18–4.22 (m, 1H), 4.26–4.31 (m, 1H). t-butyl 6-cyano-(5R)-hydroxy-3-oxo-hexanoate t-Butyl-6-cyano-(3R,5R)-dihydroxyhexanoate is an advanced chiral precursor for the …
(7R, 8S, 8′S, 7″S, 8″R)-abiesol A 4″-O-β-d-glucopyranoside, capselloside.
It’s only fair to share… (7R, 8S, 8′S, 7″S, 8″R)-abiesol A 4″-O-β-d-glucopyranoside, and it was named capselloside. Capselloside (1): Brownish gum; [α]25D −34.0 (c = 0.05, MeOH); UV (MeOH) λmax (log ε) 280 (1.4), 228 (3.3), 214 (3.1) nm; IR (KBr) νmax 3261, 2946, 2816, 1638, 1489, 1261 cm−1; CD (MeOH) λmax (Δ ε) 291 (−), 280 (−) 257 (−) 230 (−) …
Synthesis, characterization and anti-inflammatory evaluation of novel substituted tetrazolodiazepine derivatives
It’s only fair to share… SRM University Department of Chemistry Chennai, Tamil Nadu, India 3b R = NITRO http://nopr.niscair.res.in/handle/123456789/42358 Dr. S. Sathishkumar Assistant Professor in Chemistry, Kongu Engineering College, Perundurai, Erode – 638052 DR. HELEN P. KAVITHA Dr. Helen P. Kavitha Professor and Head of the Department E-mail: helen.p@rmp.srmuniv.ac.in Area: Chemistry Affiliation: Department of Chemistry, Ramapuram Campus, SRM …
NaBH4, twin screw technology (i.e., granulator, melt extruder, etc.) to yield the desired product in a continuous manner
It’s only fair to share… In this work the application of green chemistry principles such as process intensification and the replacement of reagents and solvents to more benign alternatives were coupled with the advantages of continuous manufacturing. The reduction of lipophilic aromatic aldehydes using an aqueous alkaline solution of NaBH4 was achieved by means of …
Ascaridole
It’s only fair to share… Scheme 2. Photo-Oxidation of α-terpinene 1 to Ascaridole 2 and the Common Byproduct p-Cymene 3 Continuous Photo-Oxidation in a Vortex Reactor: Efficient Operations Using Air Drawn from the Laboratory Darren S. Lee† , Zacharias Amara†, Charlotte A. Clark†, Zeyuan Xu‡, Bruce Kakimpa‡, Herve P. Morvan‡, Stephen J. Pickering‡, Martyn Poliakoff*†, and Michael W. George*†§ †School of Chemistry, ‡Department of Mechanical, Materials and Manufacturing Engineering, University of …
One-pot synthesis of 2-hydroxymethyl-5-methylpyrazine from renewable 1,3-dihydroxyacetone
It’s only fair to share… One-pot synthesis of 2-hydroxymethyl-5-methylpyrazine from renewable 1,3-dihydroxyacetone Green Chem., 2017, Advance Article DOI: 10.1039/C7GC00578D, Communication Lei Song, Mingyuan Zheng, Jifeng Pang, Joby Sebastian, Wentao Wang, Minjie Qu, Jian Zhao, Xinhong Wang, Tao Zhang An efficient and environmentally benign method for the synthesis of 2-hydroxymethyl-5-methylpyrazine (HMMP) from biomass derived 1,3-dihydroxyacetone …
Green Synthesis of Veratraldehyde Using Potassium Promoted Lanthanum–Magnesium Mixed Oxide Catalyst
It’s only fair to share… Veratraldehyde is an important chemical used in perfumery, agrochemical, and pharmaceutical industries. Current processes of manufacture of veratraldehyde use homogeneous catalysts, which make them highly polluting, creating problems of disposal of effluents and product purity. In the current work, veratraldehyde was synthesized from O-alkylation of vanillin with an environmentally …
Iridium-catalyzed highly efficient chemoselective reduction of aldehydes in water using formic acid as the hydrogen source
It’s only fair to share… Iridium-catalyzed highly efficient chemoselective reduction of aldehydes in water using formic acid as the hydrogen source Green Chem., 2017, Advance Article DOI: 10.1039/C7GC01289F, Paper Zhanhui Yang, Zhongpeng Zhu, Renshi Luo, Xiang Qiu, Ji-tian Liu, Jing-Kui Yang, Weiping Tang A highly efficient iridium catalyst is developed for the chemoselective reduction …
A Convenient and “Greener” Synthesis of Methyl Nitroacetate
It’s only fair to share… Methyl Nitroacetate (2) Warning: Although no incidents occurred, the intermediates generated, as well as the end product, are energetic and should be handled as if they are explosive materials. It is essential that all reactions be conducted behind a blast shield and that proper protective equipment, including a face …