CURCUMIN

It’s only fair to share… Curcumin Enol form Keto form Title: Curcumin CAS Registry Number: 458-37-7 CAS Name: (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione Additional Names: turmeric yellow; diferuloylmethane; C.I. 75300; C.I. Natural Yellow 3 Molecular Formula: C21H20O6 Molecular Weight: 368.38 Percent Composition: C 68.47%, H 5.47%, O 26.06% Literature References: Natural dyestuff from root of Curcuma longa L., Zingiberaceae. Isoln: Vogel, Ann. 44, 297 (1842); Perkin, Phipps, J. Chem. Soc. (Trans.) 85, I, 64 (1904); Rao, Shintre, J. Soc. …

(±)-SIPI 6360

It’s only fair to share… (±)-SIPI 6360 D2/5-HT2A receptor dual antagonist 7-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy]-3-methyl-3,4-dihydro-1H-quinolin-2-one 2(1H)-Quinolinone, 7-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3,4-dihydro-3-methyl- Molecular Formula: C25H28FN3O3 Molecular Weight: 437.506523 g/mol CAS 1401333-14-9 2(1H)-Quinolinone, 7-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3,4-dihydro-3-methyl- ((±)-SIPI 6360) 7-(3-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)propoxy)-3-methyl-3,4-dihydroquinolin-2(1H)-one ((±)-SIPI 6360) Mp 154–155 °C; 1H NMR (400 Hz, CDCl3) δ 8.41 (br, 1H), 7.70 (dd, J = 8.8, 5.2 Hz, 1H), 7.27–7.23 (m, 1H), 7.08–7.03 (m, …

REMOGLIFLOZIN ETABONATE

It’s only fair to share… REMOGLIFLOZIN ETABONATE 5-methyl-4-[4-(1-methylethoxy)benzyl]-1-(1-methylethyl)-1H-pyrazol-3-yl 6-O-(ethoxycarbonyl)-β-D-glucopyranoside, ethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-methyl-1-propan-2-yl-4-[(4-propan-2-yloxyphenyl)methyl]pyrazol-3-yl]oxy-oxan-2-yl]methyl carbonate  https://clinicaltrials.gov/show/NCT02537470   UNII:TR0QT6QSUL CAS 442201-24-3 189075  BHV-091009  GSK-189075  GSK-189075A  KGT-1681  BHV Pharma  Kissei (Originator)  , GlaxoSmithKline Remogliflozin etabonate Phase II A SGLT-2 antagonist potentially for the treatment of type 2 diabetes, non-alcoholic steatohepatitis (NASH), obesity. GSK-189075; GSK-189075A Molecular FormulaC26H38N2O9 Average mass522.588 Remogliflozin etabonate (INN/USAN)[1] …

Continuous Flow Doebner–Miller Reaction and Isolation Using Continuous Stirred Tank Reactors

It’s only fair to share… Continuous flow Doebner–Miller synthesis of different quinaldines from respective anilines is demonstrated using sulfuric acid as a homogeneous catalyst. The extent of reaction was monitored for various parameters, namely, temperature, residence time, mole ratio of sulfuric acid to substrate, mole ratio of crotonaldehyde to substrate, and so forth. Continuous stirred …

Pharma Marketing Conference- Its need of the Hour!, “Pharma Marketing Summit 2016” 13-14 Oct 2016, Holiday Inn Mumbai International Airport, Mumbai, India

It’s only fair to share… Pharma Marketing Conference- Its need of the Hour!, “Pharma Marketing Summit 2016” 13-14 Oct 2016, Holiday Inn Mumbai International Airport, Mumbai, India Today, it’s not only about promoting your products but to position your company as a disease prevention and management company. The regulatory environment in the pharmaceutical sector is …

Olanexidine, オラネキシジングルコン酸塩

It’s only fair to share… Olanexidine Gluconate OPB-2045G, Gluconate olanexidin,  Olanedine,  OPB-2045,  OPB 2045G,  (Olanedine®)Approved in Japan PMDA 2015-07-03, Olanedine® by Otsuka A disinfectant used to prevent of postoperative bacterial infections. CAS .146510-36-3(Olanexidine free form),  Imidodicarbonimidic diamide, N-((3,4-dichlorophenyl)methyl)-N’-octyl C17H27Cl2N5 Formula Weight: 372.341 CAS 799787-53-4(Olanexidine Gluconate) 568.49 Formula C17H27Cl2N5 ● C6H12O7 1-(3,4-Dichlorobenzyl)-5-octylbiguanide mono-D-gluconate オラネキシジングルコン酸塩 Olanexidine Gluconate C17H27Cl2N5▪C6H12O7 : 568.49 [799787-53-4] Indication:Bacterial infection …

Fortune India presents award to Ajanta pharma

It’s only fair to share… Fortune India has published list of 500 mid-size companies who ranked them on various parameters based on the results of 2013-2014. Ajanta pharma features very prominently in the lists. Ajanta’s ranking on various pararmeters is given below: Ranked 3’d largest Wealth Creator on 5 year CAGR 93.14% Ranked 10th on …

Pitolisant

It’s only fair to share…   Pitolisant CAS 362665-56-3 FDA APPROVED 2019 AUG 1-(3-(3-(4-Chlorophenyl)propoxy)propyl)piperidine MF  C17H26ClNO MW  295.1703 HBS-101 Pitolisant Tiprolisant UNII-4BC83L4PIY   (Wakix®)Approved EU 31/3/2016, Narcolepsy A histamine H3 receptor antagonist/inverse agonist used to treat narcolepsy. BF-2649; BF-2.649; FUB-649, Ciproxidine, Tiprolisant CAS 362665-56-3, 362665-57-4 (oxalate)  CAS 903576-44-3(Pitolisant Hydrochloride) APPROVED IN EU,  European Medicine Agency (EMA) on Mar 31, 2016. BF 2.649 BF …