It’s only fair to share… Acetaminosalol Molecular FormulaC15H13NO4 Average mass271.268 Da ацетаминосалол [Russian] [INN], أسيتامينوسالول [Arabic] [INN], 醋氨沙洛 [Chinese] [INN] (1E)-N-{4-[(2-Hydroxybenzoyl)oxy]phenyl}ethanimidic acid 118-57-0 [RN] 204-261-3 [EINECS] CAS Registry Number: 118-57-0 CAS Name: 2-Hydroxybenzoic acid 4-(acetylamino)phenyl ester Additional Names: p-acetamidophenyl salicylate; acetylaminophenyl salicylate; acetyl-p-aminosalol; p-acetylaminophenol salicylic acid ester; phenetsal Trademarks: Salophen (Bayer); Phenosal Molecular Formula: C15H13NO4 Molecular Weight: 271.27 Percent Composition: C 66.41%, H 4.83%, N 5.16%, O 23.59% Literature References: Prepn: Brewster, J. Am. …
LINZAGOLIX
It’s only fair to share… LINZAGOLIX CAS 935283-04-8 C22H15F3N2O7S Hormone Antagonists 3-[5-[(2,3-difluoro-6-methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl]-2,4-dioxo-1H-thieno[3,4-d]pyrimidine-5-carboxylic acid WHO 10711 Treatment of Endometriosis Pain and Uterine Myoma-Associated Heavy Menstrual Bleeding OriginatorKissei Pharmaceutical DeveloperKissei Pharmaceutical; ObsEva Class2 ring heterocyclic compounds; Antihormones; Antineoplastics; Carboxylic acids; Fluorinated hydrocarbons; Ketones; Pyrimidines; Small molecules; Thiophenes Mechanism of ActionLHRH receptor antagonists PreregistrationUterine leiomyoma Phase IIIEndometriosis Phase IIAdenomyosis …
Ropeginterferon alfa-2b
It’s only fair to share… PCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE (Disulfide bridge: 2-99, 30-139) Ropeginterferon alfa-2b AOP2014 CAS 1335098-50-4 UNII981TME683S FDA APPROVED, 2021/11/12, BESREMI PEPTIDE, Antineoplastic, Antiviral Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, …
SULCONAZOLE
It’s only fair to share… SULCONAZOLE сульконазол , سولكونازول , 硫康唑 Molecular FormulaC18H15Cl3N2S Average mass397.749 Da 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]- [ACD/Index Name] 4332 5D9HAA5Q5S 61318-90-9 [RN] (±)-1-[2,4-Dichloro-b-[(p-chlorobenzyl)thio]phenethyl]imidazole 1-[2-[[(4-Chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole : Sulconazole CAS Registry Number: 61318-90-9 CAS Name: 1-[2-[[(4-Chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole Additional Names: (±)-1-[2,4-dichloro-b-[(p-chlorobenzyl)thio]phenethyl]imidazole Molecular Formula: C18H15Cl3N2S Molecular Weight: 397.75 Percent Composition: C 54.35%, H 3.80%, Cl 26.74%, N 7.04%, S 8.06% Literature References: Prepn: K. A. M. Walker, DE2541833; idem,US4055652 (1976, 1977 both to …
TNO 155
It’s only fair to share… TNO 155 2-Oxa-8-azaspiro[4.5]decan-4-amine, 8-[6-amino-5-[(2-amino-3-chloro-4-pyridinyl)thio]-2-pyrazinyl]-3-methyl-, (3S,4S)- (3S,4S)-8-[6-Amino-5-[(2-amino-3-chloro-4-pyridinyl)thio]-2-pyrazinyl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine (3S,4S)-8-(6-amino-5-((2-amino-3-chloropyridin-4-yl)thio)pyrazin-2-yl)-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine Molecular Weight 421.95 Formula C₁₈H₂₄ClN₇OS CAS No. 1801765-04-7 PTPN11 inhibitor TNO155 SHP2 inhibitor TNO155 TNO-155 TNO155 UNII-FPJWORQEGI TNO155 is a potent selective and orally active allosteric inhibitor of wild-type SHP2 (IC50=0.011 µM). TNO155 has the potential for the study of RTK-dependent malignancies, especially …
CILENGITIDE
It’s only fair to share… IUPAC Condensed cyclo[Arg-Gly-Asp-D-Phe-N(Me)Val] HELM PEPTIDE1{R.G.D.[dF].[meV]}$PEPTIDE1,PEPTIDE1,5:R2-1:R1$$$ IUPAC cyclo[L-arginyl-glycyl-L-alpha-aspartyl-D-phenylalanyl-N-methyl-L-valyl] CILENGITIDE Molecular FormulaC27H40N8O7 Average mass588.656 Da 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid 188968-51-6 [RN] 4EDF46E4GI 7823 циленгитид سيلانجيتيد 西仑吉肽 EMD 121974, EMD-121974, UNII-4EDF46E4GI 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid Cilengitide has been in phase III clinical trials by Merck Serono and NCI for the treatment of glioblastoma multiforme. However, this research has been …
Methotripremazine
It’s only fair to share… Methotripremazine 60-99-1 7104-38-3 (maleate), 1236-99-3 HCl) CL 36467 CL 39743 N05AA02 RP 7044 RP-7044 SK&F 5116 XP-03 XP03 Product Ingredients INGREDIENT UNII CAS INCHI KEY Methotrimeprazine hydrochloride 42BB1Y2586 1236-99-3 ODLGFPIWRAEFAN-PFEQFJNWSA-N Methotrimeprazine maleate 5KN5Y9V01K 7104-38-3 IFLZPECPTYCEBR-VIEYUMQNSA-N Methotrimeprazine CAS Registry Number: 60-99-1 CAS Name: (bR)-2-Methoxy-N,N,b-trimethyl-10H-phenothiazine-10-propanamine Additional Names: (-)-10-(3-dimethylamino-2-methylpropyl)-2-methoxyphenothiazine; levomepromazine; 2-methoxytrimeprazine; levomeprazine Manufacturers’ Codes: RP-7044 Trademarks: Sinogan-Debil; Tisercin (EGYT); Neozine …
Methiomeprazine
It’s only fair to share… Methiomeprazine N,N,2-trimethyl-3-(2-methylsulfanylphenothiazin-10-yl)propan-1-amine CAS 7009-43-0 Molecular Formula, C19-H24-N2-S2, Molecular Weight, 344.5446, 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-2-(methylthio)-, (±)- Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-2-(methylthio)-, (±)- (8CI) N,N,β-Trimethyl-2-(methylthio)-10H-phenothiazine-10-propanamine (±)-10-(3-Dimethylamino-2-methylpropyl)-2-(methylthio)phenothiazine 10584-RP 2-Methylthio-10-(2-methyl-3-dimethylaminopropyl)phenothiazine Methiomeprazine SKF 6270 (+-)-10-(3-Dimethylamino-2-methylpropyl)-2-(methylthio)phenothiazine Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-2-(methylthio)-, (+-)- 10584 RP EINECS 230-285-9 Methiomeprazinum Methiomeprazinum [INN-Latin] Metiomeprazina Metiomeprazina [INN-Spanish] RP 10584 SKF 6270 UNII-X2R9QTF0OL Methiomeprazine hydrochloride 14056-64-5 Methiomeprazine maleate 101037-46-1 join me on Linkedin …
Dichlorquinazine
It’s only fair to share… CORRECT STR OF Dichlorquinazine 7-chloro-N-[1-[4-[2-[(7-chloroquinolin-4-yl)amino]propyl]piperazin-1-yl]propan-2-yl]quinolin-4-amine;methanesulfonic acid 1,4-Piperazinediethanamine, N,N’-bis(7-chloro-4-quinolinyl)-α,α’-dimethyl- (9CI) Quinoline, 4,4-[1,4-piperazinediylbis[(1-methylethylene)imino]]bis[7-chloro- (7CI) Quinoline, 4,4′-[1,4-piperazinediylbis[(1-methylethylene)imino]]bis[7-chloro- (8CI) N1,N4-Bis(7-chloro-4-quinolinyl)-α1,α4-dimethyl-1,4-piperazinediethanamine 1,4-Bis[2-(7-chloro-4-quinolylamino)propyl]piperazine Bis[(chloro-7”-quinolyl-4”)amino-2′-propyl]-1,4-piperazine Dichlorquinazine N,N’-Bis(7-chloro-4-quinolyl)-α,α’-dimethylpiperazine-1,4-diethylamine NSC 129790 RP 12278 WR 3863 WRONG STRUCTURE WRONG STRUCTURE Dichlorquinazine BRN 0867697 Dichlorquinazine EINECS 234-130-6 NSC 129790 RP 12278 UNII-HT3GAD2SCM WR 3863 cas 10547-40-7 C28H32Cl2N6, mw 523.5 7-chloro-N-[2-[4-[2-[(7-chloroquinolin-4-yl)amino]propan-2-yl]piperazin-1-yl]propan-2-yl]quinolin-4-amine …
RP 12146
It’s only fair to share… RP 12146 RP-12146 is an oral poly (ADP-ribose) polymerase (PARP) inhibitor in phase I clinical development at Rhizen Pharmaceuticals for the treatment of adult patients with locally advanced or metastatic solid tumors. Solid TumorExtensive-stage Small-cell Lung CancerLocally Advanced Breast CancerMetastatic Breast CancerPlatinum-sensitive Ovarian CancerPlatinum-Sensitive Fallopian Tube CarcinomaPlatinum-Sensitive Peritoneal Cancer …