How to Apply for an International Patent

It’s only fair to share… How to Apply for an International Patent Part1 Determining the Patentability of your Invention 1Determine if you have a patentable invention. U.S. law sets forth the following requirements for something that can be patented: It must be invented or discovered by a person; It must be a new and useful …

Asymmetric total synthesis of (-)-δ-lycorane

It’s only fair to share… 1H NMR 13C NMR Org. Chem. Front., 2017, Advance Article DOI: 10.1039/C7QO00021A, Research Article Junliang Wang, Jianneng Li, Xianwang Shen, Cong Dong, Jun Lin, Kun Wei A first asymmetric synthesis of (-)-δ-lycorane by using a chiral bifunctional squaramide-catalysed cascade reaction is reported. Asymmetric total synthesis of (−)-δ-lycorane Junliang Wang,ab   Jianneng …

4-Pentenoic acid, 5-(3,4-methylenedioxyphenyl)-3-oxo-, ethyl ester

It’s only fair to share… 4-Pentenoic acid, 5-(3,4-methylenedioxyphenyl)-3-oxo-, ethyl ester cas 860547-52-0 MF C14 H14 O5 4-Pentenoic acid, 5-(1,3-benzodioxol-5-yl)-3-oxo-, ethyl ester Molecular Weight, 262.26 Melting Point (Experimental) Value: 58-60 °C Purification of the residue by flash column chromatography (10% ethyl acetate in hexanes) afforded the β-keto ester (12.0 g, 90%) as a pale yellow oil. …

DRAFTING A NON-PROVISIONAL PATENT APPLICATION

It’s only fair to share… DRAFTING A NON-PROVISIONAL PATENT APPLICATION! Part1 Determining the Patentability of your Invention 1Determine if you have a patentable invention. U.S. law sets forth the following requirements for something that can be patented: It must be invented or discovered by a person; It must be a new and useful process, machine, …

How do I get a patent in India ?

It’s only fair to share…   How much does getting a patent in India costs? There is no precise and accurate answer to this question as cost for a obtaining patent is dependent on mutiple factors… What best we can have is range for costs involved in… There are two elements for cost of getting patent …

Dimethylcarbamoyl Chloride, a known carcinogen

It’s only fair to share… Identifiers CAS Number 79-44-7 ECHA InfoCard 100.001.099 PubChem 6598 Properties Chemical formula C3H6ClNO Dimethylcarbamoyl Chloride Mechanisms for the Formation of Dimethylcarbamoyl Chloride Thionyl chloride is the most common reagent in process chemistry for the conversion of a carboxylic acid to an acid chloride. One of the primary factors is cost, since …

GDC 0994, Ravoxertinib

It’s only fair to share…   GDC 0994 GDC-0994; Ravoxertinib; 1453848-26-4; GDC0994; UNII-R6AXV96CRH; R6AXV96CRH, RG7842; RG-7842; RG 7842 CAS 1453848-26-4 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one Molecular Formula: C21H18ClFN6O2 Molecular Weight: 440.863 g/mol   PHASE 1 Ravoxertinib also known as GDC-0994 and RG7842, is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, GDC-0994 inhibits …

TROXACITABINE троксацитабин , تروكساسيتابين , 曲沙他滨 ,

It’s only fair to share… Troxacitabine CAS 145918-75-8 Molecular FormulaC8H11N3O4 Average mass213.191 Da троксацитабин تروكساسيتابين 曲沙他滨 2(1H)-Pyrimidinone, 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]- Hmd-cytosine; NCGC00183848-01; Beta-L-Dioxolane-cytidine; 4-amino-1-[(2S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one; 2R(-)-cis-Hmd-cytosine, (-)-ODDC 4-amino-1-[(2S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one Troxacitabine (brand name Troxatyl) is a nucleoside analogue with anticancer activity. Its use is being studied in patients with refractory lymphoproliferative diseases.[1] Troxacitabine (brand name Troxatyl) is a nucleoside analogue with anticancer …

Astellas Pharma Inc. new Glucokinase Activator, ASP ? for Type 2 Diabetes

It’s only fair to share…   ASP ? (2R)-2-(4-cyclopropanesulfonyl-3-cyclopropylphenyl)-N-[5-(hydroxymethyl)pyrazin-2-yl]-3-[(R)-3-oxocyclopentyl]propanamide CAS 1174229-89-0 MW C25 H29 N3 O5 S Benzeneacetamide, 3-cyclopropyl-4-(cyclopropylsulfonyl)-N-[5-(hydroxymethyl)-2-pyrazinyl]-α-[[(1R)-3-oxocyclopentyl]methyl]-, (αR)- Molecular Weight, 483.58 [α]D20 −128.7 (c 1.00, MeOH); 1H NMR (DMSO-d6, 400 MHz) δ 11.07 (s, 1H), 9.20 (d, J = 1.4 Hz, 1H), 8.41 (d, J = 1.4 Hz, 1H), 7.79 (d, J = 8.2 …

FDA approves first treatment Noctiva (Desmopressin acetate) nasal spray for frequent urination at night due to overproduction of urine

It’s only fair to share… Desmopressin acetate FDA approves first treatment for frequent urination at night due to overproduction of urine 03/03/2017 The U.S. Food and Drug Administration today approved Noctiva (desmopressin acetate) nasal spray for adults who awaken at least two times per night to urinate due to a condition known as nocturnal polyuria …