Aceclofenac, ацеклофенак , أسيكلوفيناك , 醋氯芬酸 , アセクロフェナク

It’s only fair to share… Aceclofenac アセクロフェナク Molecular FormulaC16H13Cl2NO4 Average mass354.185 Da (2-{2-[(2,6-Dichlorophenyl)amino]phenyl}acetoxy)acetic acid [ACD/IUPAC Name] (2-{2-[(2,6-Dichlorphenyl)amino]phenyl}acetoxy)essigsäure [German] [ACD/IUPAC Name] 5608 89796-99-6 [RN] Aceclofenac [BAN] [INN] [JAN] [Wiki] acéclofénac [French] [INN] Aceclofenaco [Spanish] [INN] Aceclofenacum [Latin] [INN] Acide (2-{2-[(2,6-dichlorophényl)amino]phényl}acétoxy)acétique [French] [ACD/IUPAC Name] Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, carboxymethyl ester [ACD/Index Name] RPK779R03H ацеклофенак[Russian][INN] أسيكلوفيناك[Arabic][INN] 醋氯芬酸[Chinese][INN] [({2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid [2-(2,6-Dichloro-phenylamino)-phenyl]-acetic acid carboxymethyl ester Aceclofenac CAS Registry Number: 89796-99-6 CAS Name: 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester Additional Names: 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid; glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate …

Diclofenac Sodium

It’s only fair to share… Diclofenac Sodium 15307-79-6; Sodium diclofenac; Diclofenac sodium salt; Voltaren; Solaraze Molecular Formula: C14H10Cl2NNaO2 Molecular Weight: 318.129 g/mol Diclofenac, sold under the trade names Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout.[3] It is taken by mouth or applied to the skin.[3] Improvements in pain typically occur within …

Clotrimazole

It’s only fair to share… Clotrimazole Molecular FormulaC22H17ClN2 Average mass344.837 Da 1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole (9CI) 1-(o-Chloro-a,a-diphenylbenzyl)imidazole 1-[(2-Chlorophenyl)(diphenyl)methyl]-1H-imidazole 1-[(o-Chlorophenyl)diphenylmethyl]imidazole 1-[a-(2-Chlorophenyl)benzhydryl]imidazole 1H-Imidazole, 1-[(2-chlorophenyl)diphenylmethyl]- 1H-Imidazole, 1-[(2-chlorophenyl)-diphenylmethyl] 23593-75-1 [RN] 245-764-8 [EINECS] 2912 Bis-fenil-(2-clorofenil)-1-imidazolil-metano [Italian] Bisphenyl-(2-chlorphenyl)-1-imidazolyl-methan [German] Canesten [Trade name] Canifug [Trade name] Clotrimazole [BAN] [INN] [JAN] [USAN] [Wiki] Clotrimazolum [Latin] Empecid [Trade name] Fungicip [Trade name] G07GZ97H65 Gyne-Lotrimin [Trade name] Imidazole, 1- (o-chloro-α,α-diphenylbenzyl)- Lotrimin [Trade name] Mono-baycuten [Trade name] Mycelex [Trade name] Mycelex G [Trade name] Mycosporin [Trade name] Pedisafe [Trade name] …

SELETALISIB, селеталисиб , سيلستاليسيب , 司来利塞 ,

It’s only fair to share… SELETALISIB CAS 1362850-20-1 UCB-5857 , Plaque psoriasis,Sjoegren’s syndrome,Immunodeficiency disorders PHASE 3 UCB 23H14ClF3N6O , 482.85 Phosphatidylinositol 3 kinase delta (PI3Kδ) inhibitors 10023 1362850-20-1 [RN] N-{(1R)-1-[8-Chlor-2-(1-oxido-3-pyridinyl)-3-chinolinyl]-2,2,2-trifluorethyl}pyrido[3,2-d]pyrimidin-4-amine N—{(R)-1-[8-Chloro-2-(pyridin-3-yl)quinolin-3-yl]-2,2,2-trifluoroethyl}N-(1-oxypyrido-[3,2-d]pyrimidin-4-yl)amine Pyrido[3,2-d]pyrimidin-4-amine, N-[(1R)-1-[8-chloro-2-(1-oxido-3-pyridinyl)-3-quinolinyl]-2,2,2-trifluoroethyl]- 3-{8-chloro-3-[(1R)-2,2,2-trifluoro-1-({pyrido[3,2-d]pyrimidin-4-yl}amino)ethyl]quinolin-2-yl}pyridin-1-ium-1-olate селеталисиб [Russian] [INN] سيلستاليسيب [Arabic] [INN] 司来利塞 [Chinese] [INN] N-[(1R)-1-[8-chloro-2-(1-oxidopyridin-1-ium-3-yl)quinolin-3-yl]-2,2,2-trifluoroethyl]pyrido[3,2-d]pyrimidin-4-amine Seletalisib has been used in trials studying the treatment and basic science of Primary Sjogren’s Syndrome. Originator UCB Class Anti-inflammatories; Small molecules Mechanism …

PF-06650833

It’s only fair to share… PF-06650833 1-{[(2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide CAS 1817626-54-2 Chemical Formula: C18H20FN3O4 Molecular Weight: 361.3734 Originator Pfizer Class Anti-inflammatories; Antirheumatics Mechanism of Action Interleukin-1 receptor-associated kinase inhibitors Phase II Rheumatoid arthritis Phase I Lupus vulgaris 01 Aug 2018 Pfizer completes a phase II trial in Rheumatoid arthritis (Treatment-experienced) in USA, Ukraine, Taiwan, Serbia, Russia, Romania, Poland, Mexico, South Korea, Georgia, Bosnia-Herzegovina, …

PF 06650808

It’s only fair to share… . Picture credit….Bethany Halford PF 06650808 CAS 1822383-80-1 A biologic for cancer treatment (Pfizer Inc.) Originator Pfizer Class Antineoplastics Mechanism of Action Notch-3 receptor antagonists No development reported Solid tumours 24 Jun 2018 Biomarkers information updated 28 Apr 2018 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease) in USA (IV) 01 Jul 2017 Pfizer …

Beclabuvir

It’s only fair to share… BMS-791325, Beclabuvir IN PHASE 2 for Hepatitis C (HCV) An NS5B inhibitor. BMS-791325 preferably is CAS 958002-33-0 958002-36-3 (as hydrochloride) C36 H45 N5 O5 S, 659.838 Cycloprop(d)indolo(2,1-a)(2)benzazepine-9-carboxamide, 12-cyclohexyl-N-((dimethylamino)sulfonyl)-4b,5,5a,6-tetrahydro-3-methoxy-5a-((3-methyl-3,8-diazabicyclo(3.2.1)oct-8-yl)carbonyl)-, (4bS,5aR)- (4bS,5aR)-12-Cyclohexyl-N-(dimethylsulfamoyl)-3-methoxy-5a-((3-methyl-3,8-diazabicyclo(3.2.1)oct-8-yl)carbonyl)-4b,5,5a,6-tetrahydrocyclopropa(d)indolo(2,1-a)(2)benzazepine-9-carboxamide (4bS,5aR)-12-Cyclohexyl-N-(dimethylsulfamoyl)-3-methoxy-5a-((3-methyl-3,8-diazabicyclo(3.2.1)oct-8-yl)carbonyl)-4b,5,5a,6-tetrahydrocyclopropa(d)indolo(2,1-a)(2)benzazepine-9-carboxamide (1aR,12bS)-8-Cyclohexyl-N-(dimethylsulfamoyl)-11-methoxy-1a-[(3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl]-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide Cycloprop [d] indolo [2, 1 -a] [2]benzazepine-5-carboxamide, 8-cyclohexyl-N- [(dimethylamino)sulfonyl]-l,la,2,12b-tetrahydro-ll-methoxy-la-[(3-methyl-3,8- diazabicyclo[3.2.1]oct-8-yl)carbonyl]-, (laR,12bS)- Bristol-Myers Squibb (Originator) RNA-Directed RNA Polymerase (NS5B) …

Gilteritinib fumarate ギルテリチニブフマル酸塩

It’s only fair to share… 1254053-84-3 Gilteritinib ASP-2215 Treatment of Acute Myeloid Leukemia 6-ethyl-3-{3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino}-5-[(oxan-4-yl)amino]pyrazine-2-carboxamide C29H44N8O3, 552.71 Phase III Xospata pmda 2018/9/21  JAPAN 2018 A FLT3/AXL inhibitor potentially for the treatment of acute myeloid leukemia. CAS No. 1254053-43-4  FREE FORM 1254053-84-3  FUMARATE Astellas Pharma  INNOVATOR Mechanism Of Action Axl receptor tyrosine kinase inhibitors, Fms-like tyrosine kinase 3 inhibitors, Proto …

Vibegron ビベグロン

It’s only fair to share…   Vibegron, MK-4618, KRP 114V UNII-M5TSE03W5U; M5TSE03W5U; D10433 1190389-15-1;  cas no Molecular Formula: C26H28N4O3   Molecular Weight: 444.52552 Merck Sharp & Dohme Corp.  INNOVATOR phase 2 for the treatment of overactive bladder  (6S)-N-[4-([(2S,5R)-5-[(R)-Hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl)phenyl]-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxamide (6S)-N-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-4-oxo-7,8-dihydro-6H-pyrrolo[1,2-a]pyrimidine-6-carboxamide Target-based Actions Beta 3 adrenoceptor agonist Indications Overactive bladder; Urinary incontinence UPDATE 2018/9/21  pmda Beova JAPAN 2018Kyorin Pharmaceutical, under license …

Omadacycline tosylate

It’s only fair to share… Omadacycline tosylate 728.8521, C29H40N4O7. C7H8O3S CAS: 1075240-43-5 389139-89-3 FREE FORM FDA 2018/10/3, Nuzyra オマダサイクリントシル酸塩; UNII-5658Y89YCD (4S,4aS,5aR,12aS)-4,7-Bis(dimethylamino)-9-{[(2,2-dimethylpropyl)amino]methyl}-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide 4-methylbenzenesulfonate (1:1) 1075240-43-5 [RN] 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-9-[[(2,2-dimethylpropyl)amino]methyl]-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-, 4-methylbenzenesulfonate (1:1) (salt) 5658Y89YCD Amadacycline tosylate PTK 0796 / PTK-0796 Omadacycline FREE FORM, 389139-89-3 FREE FORM Omadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections, Community-Acquired Infections, and Skin Structures and …