Pitolisant Hydrochloride

It’s only fair to share…   Pitolisant 1-(3-(3-(4-Chlorophenyl)propoxy)propyl)piperidine MF  C17H26ClNO MW  295.1703 (Wakix®)Approved EU 31/3/2016, Narcolepsy A histamine H3 receptor antagonist/inverse agonist used to treat narcolepsy. BF-2649; BF-2.649; FUB-649, Ciproxidine, Tiprolisant CAS 362665-56-3, 362665-57-4 (oxalate)  CAS 903576-44-3(Pitolisant Hydrochloride) 1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine hydrochloride (1:1) Molecular Weight 332.31 Formula C17H26ClNO ● HCl Bioprojet INNOVATOR Jean-Charles Schwartz, Jeanne-Marie Lecomte Pitolisant (INN) or tiprolisant (USAN) is a histamine …

ROMIDEPSIN

It’s only fair to share…    Romidepsin; Depsipeptide; FK228; Chromadax; FR901228; Istodax; Molecular Formula: C24H36N4O6S2 Molecular Weight: 540.69584 g/mol CAS 128517-07-7 (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone (E)-N-(2-amino-4-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide Romidepsin, also known as Istodax, is an anticancer agent used in cutaneous T-cell lymphoma (CTCL) and other peripheral T-cell lymphomas (PTCLs). Romidepsin is a natural product obtained from the bacteria Chromobacterium violaceum, and …

Naloxegol oxalate (MovantikTM, Moventig)

It’s only fair to share… Naloxegol Movantik; NKTR-118; NKTR118; UNII-44T7335BKE; NKTR 118 854601-70-0  cas 1354744-91-4 (Naloxegol Oxalate) (4R,4aS,7S,7aR,12bS)-7-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol MF C34H53NO11 MW 651.78472 g/mol Morphinan-3,14-diol, 4,5-epoxy-6-(3,6,9,12,15,18,21-heptaoxadocos-1-yloxy)-17-(2-propen-1-yl)-, (5α,6α)-, ethanedioate (1:1) (salt) Naloxegol oxalate [USAN] UNII-65I14TNM33 AZ-13337019 oxalate Naloxegol (oxalate) NKTR-118 oxalate;AZ-13337019 oxalate UNII:65I14TNM33 Naloxegol oxalate (MovantikTM, Moventig) Naloxegol (INN; PEGylated naloxol;[1] trade names Movantik and Moventig) is …

Opicapone

It’s only fair to share… Opicapone 2,5-dichloro-3-(5-(3,4-dihydroxy-5-nitrophenyl)-1,2,4-oxadiazol-3-yl)-4,6-dimethylpyridine-1-oxide BIA-9-1067; ONO-2370; BIA-91067 CAS No.923287-50-7 MF C15H10Cl2N4O6 MW: 411.9977 TRADE NAME (Ongentys®) Approved EU 2016-06-24 BIAL PORTELA PORTELA & CA. S.A. [PT/PT]; Av. Da Siderurgia Nacional, P-4745-457 S. Mamede do Coronado (PT) LEARMONTH, David Alexander; (PT). KISS, Laszlo Erno; (PT). LEAL PALMA, Pedro Nuno; (PT). DOS SANTOS FERREIRA, Humberto; (PT). …

Flow Chemistry in Industrial Scale Organic Synthesis, 17th Jan, 2017 from 9-5pm in Ramada Powai Hotel & Convention Centre, Mumbai, India.

It’s only fair to share… ABOUT COURSE https://selectbiosciences.com/trainingCoursesID.aspx?tc=FCTC17&pid=5024&conf=FCI17&se=india FCI 2017 http://selectbiosciences.com/conferences/index.aspx?conf=FCI17&se=india VENUE http://selectbiosciences.com/conferences/venue.aspx?pid=4870&conf=FCI17&se=india SELECTBIO is pleased to present the training course on Flow Chemistry in Industrial Scale Organic Synthesis, which is scheduled to be held on 17th January, 2017 from 9:00am to 5:00pm in Ramada Powai Hotel & Convention Centre, Mumbai, India. This course will …

AZD 2716

It’s only fair to share… AZD2716 CAS 1845753-81-2 MF C24 H23 N O3,   MW 373.44 [1,1′-Biphenyl]-3-propanoic acid, 2′-(aminocarbonyl)-α-methyl-5′-(phenylmethyl)-, (αR)- Antiplaque candidate drug AstraZeneca INNOVATOR (R)-7(AZD2716) a novel, potent secreted phospholipase A2 (sPLA2) inhibitor with excellent preclinical pharmacokinetic properties across species, clear in vivo efficacy, and minimized safety risk. Based on accumulated profiling data, (R)-7 was selected …

RPL 554

It’s only fair to share… RPL-554 Molecular FormulaC26H31N5O4 Average mass477.555 RPL 554 Urea, N-[2-[(2E)-6,7-dihydro-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl]ethyl]- (2-[(2E)-9,10-DIMETHOXY-4-OXO-2-[(2,4,6-TRIMETHYLPHENYL)IMINO]-2H,3H,4H,6H,7H-PYRIMIDO[4,3-A]ISOQUINOLIN-3-YL]ETHYL)UREA 2-[9,10-dimethoxy-4-oxo-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[6,1-a]isoquinolin-3-yl]ethylurea {2-[(2E)-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-2H,3H,4H,6H,7H-pyrimido[4,3-a]isoquinolin-3-yl]ethyl}urea 2-[4-keto-9,10-dimethoxy-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[4,3-a]isoquinolin-3-yl]ethylurea 2-[9,10-dimethoxy-4-oxo-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[4,3-a]isoquinolin-3-yl]ethylurea 298680-25-8  CAS UNII:3E3D8T1GIX CFTR stimulator; PDE 3 inhibitor; PDE 4 inhibitor RPL-554 is a mixed phosphodiesterase (PDE) III/IV inhibitor in phase II clinical development at Verona Pharma for the treatment of asthma, allergic rhinitis, chronic obstructive …

ACT-334441, Cenerimod an S1P receptor 1 agonist

It’s only fair to share… ACT-334441 Cenerimod UNII-Y333RS1786; Y333RS1786 S1P receptor 1 agonist CAS 1262414-04-9 Chemical Formula: C25H31N3O5 Exact Mass: 453.22637 Actelion Pharmaceuticals Ltd. Martin Bolli, Cyrille Lescop, Boris Mathys,Keith Morrison, Claus Mueller, Oliver Nayler,Beat Steiner, (S)-3-(4-(5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl)-2-ethyl-6-methylphenoxy)propane-1,2-diol (2S)-3-[4-[5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]propane-1,2-diol (S)-3-{4-[5-(2-Cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol Mechanism Of Action Sphingosine 1 phosphate receptor modulator Who Atc Codes L03A-X (Other immunostimulants) Ephmra Codes …

Flow Chemistry Symposium + Workshop on 27-28th Aug’ 2016 at IISER – PUNE, Pune, India

It’s only fair to share… Flow Chemistry Society – India Chapter is assisting the proliferation of Process Intensification and Flow Chemistry across the country After  an  enthusiastic  response  at the  2nd FCS-India Symposium & Workshop held at IICT-Hyderabad  in June’16  with  27companies and 115 delegates attending,  we are happy to announce : The 3rd   2-day FLOW CHEMISTRY …

Innogen summit India 2016, 18-19 Aug, Mumbai, India

It’s only fair to share…   Innogen summit India 2016, 18-19 Aug, Mumbai, India, HOTEL HOLIDAY INN, Mumbai International Airport,Organised by Inventicon Business Intelligence Pvt. Ltd………topic is Supergenerics, Innovation in Generics, commercialization, regulatory, other insights,   Dr. Ashok Kumar, President – Centre for Research & Development, Ipca Laboratories Ltd, at Innogen summit India 2016, 18-19 …