LUPIN LIMITED, WO 2016181313, NEW PATENT, SOFOSBUVIR

It’s only fair to share… WO2016181313,  A PROCESS FOR THE PREPARATION OF SOFOSBUVIR INTERMEDIATES & ITS POLYMORPH LUPIN LIMITED [IN/IN]; Kalpataru Inspire 3rd Floor, Off Western Express Highway Santacruz (East) Mumbai 400 055 (IN) SINGH, Girij, Pal; (IN). SRIVASTAVA, Dhananjai; (IN). MEHARE, Kishor, Gulabrao; (IN). MALIK, Vineet; (IN). DEOKAR, Sharad, Chandrabhan; (IN). DANGE, Abhijeet, Avinash; …

SUVEN LIFE SCIENCES LTD, WO 2016178064, POLYMORPH OF NINTEDANIB ETHANESULPHONATE, NEW PATENT

It’s only fair to share… NINTEDANIB ETHANESULPHONATE NEW PATENT WO2016178064, CLICK FOR PATENT POLYMORPH OF NINTEDANIB ETHANESULPHONATE, PROCESSES AND INTERMEDIATES THEREOF SUVEN LIFE SCIENCES LIMITED [IN/IN]; 5th floor, Serene Chamber, Road No.5, Off Avenue No. 7, Banjara Hills, Telangana Hyderabad 500034 (IN) ARAVA, Veera Reddy; (IN). GOGIREDDY, Surendra Reddy; (IN). JASTI, Venkateswarlu; (IN) DR VEERA …

Filgotinib

It’s only fair to share… Filgotinib C21H23N5O3S MW425.504 Elemental Analysis: C, 59.28; H, 5.45; N, 16.46; O, 11.28; S, 7.54 1206161-97-8 Cyclopropanecarboxamide, N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]- G146034 GLPG0634 N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide Galapagos Nv INNOVATOR PHASE 3,  Crohn’s disease, Rheumatoid arthritis, Ulcerative colitis Filgotinib is an orally available inhibitor of JAK1/JAK2 and TYK2 in phase III clinical development at Galapagos and Gilead for the …

Pexidartinib, PLX-3397

It’s only fair to share… Pexidartinib PLX-3397 5-((5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine N-[5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine 5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine hydrochloride Phase III A Multi-targeted tyrosine kinase inhibitor potentially for the treatment of tenosynovial giant cell tumor (TGCT). CAS 1029044-16-3 C20H15ClF3N5, 417.81 Pexidartinib; 1029044-16-3; PLX-3397; 5-((5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine; 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine; 5-[(5-Chloro-1h-Pyrrolo[2,3-B]pyridin-3-Yl)methyl]-N-{[6-(Trifluoromethyl)pyridin-3-Yl]methyl}pyridin-2-Amine; Originator Plexxikon Developer Barbara Ann Karmanos Cancer Institute; Columbia University; Merck & Co; National Cancer Institute (USA); Plexxikon; University …

VALSARTAN

It’s only fair to share… VALSARTAN CAS 137862-53-4 Molecular FormulaC24H29N5O3, Average mass435.519 Da (2S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid PAPER Greening the Valsartan Synthesis: Scale-up of Key Suzuki–Miyaura Coupling over SiliaCat DPP-Pd Valerica Pandarus †, Delphine Desplantier-Giscard†, Geneviève Gingras , François Béland †*, Rosaria Ciriminna ‡, and Mario Pagliaro ‡* † SiliCycle Inc., 2500 Parc-Technologique Blvd, Quebec City, Quebec, Canada G1P 4S6 ‡ Istituto per lo Studio dei Materiali Nanostrutturati, CNR, via …

Idasanutlin, RG-7388, идасанутлин ,إيداسانوتلين , 依达奴林

It’s only fair to share… Idasanutlin(RG-7388) cas     1229705-06-9 идасанутлин [Russian] إيداسانوتلين [Arabic] 依达奴林 [Chinese] 4-{ [(2R,3S,4R,5S)-4-(4-Chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2- dimethyl-prop yl)-pyrrolidine-2-carbonyl] -amino }-3-methoxy-benzoic acid (C31H29Cl2F2N304) 4-{[(2R,3S,4R,5S)-4-(4-Chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid MW 616.4973 F. Hoffmann-La Roche Ag, Hoffmann-La Roche Inc.ROCHE PHASE1 for the oral treatment of cancer, including solid tumors and hematological tumors, including acute myelogenous leukemia Acute myelogenous leukemia; Cancer; Prostate …

Verubecestat (MK-8931)

It’s only fair to share… Verubecestat (MK-8931) Merck Alzheimer’s drugs Verubecestat (MK-8931) is an oral β- amyloid precursor protein cleaving enzyme (BACE1 or β-secretase enzyme) inhibitor, is currently in Phase III clinical trials Verubecestat MK 8931, MK-8931, SCH 900931 2-Pyridinecarboxamide, N- (3 – ((5R) -3-amino-5,6-dihydro-2,5-dimethyl-1 , 1-dioxido-2H-1,2,4-thiadiazin-5-yl) -4-fluorophenyl) -5-fluoro- N-[3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-6H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoropyridine-2-carboxamide CAS : 1286770-55-5 C17 H17 …

FDA approves Intrarosa for postmenopausal women experiencing pain during sex

It’s only fair to share… FDA approves Intrarosa for postmenopausal women experiencing pain during sex The U.S. Food and Drug Administration approved Intrarosa (prasterone) to treat women experiencing moderate to severe pain during sexual intercourse (dyspareunia), a symptom of vulvar and vaginal atrophy (VVA), due to menopause. Intrarosa is the first FDA approved product containing …

Glenmark Pharmaceuticals celebrates 39th annual day at The Lalit Hotel, Mumbai, India

It’s only fair to share… At Glenmark Pharmaceuticals 39th annual day at The Lalit Hotel, Mumbai, India, Received 10 yrs long service recognition from Mrs Cheryl pinto, coowner, Director, Corporate, HR, Glenmark Pharmaceuticals Ltd, Followed by gala evening with dance and fun With Mr Glenn saldanha, owner, CEO, and MD of Glenmark pharmaceuticals, He spoke …