It’s only fair to share… Vimseltinib 1628606-05-2 DCC-3014 2/14/2025 FDA APPROVED, Romvimza 3-methyl-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]-2-(propan-2-ylamino)pyrimidin-4-one C23H25N7O2, 431.5 To treat symptomatic tenosynovial giant cell tumor for which surgical resection will potentially cause worsening functional limitation or severe morbidity Vimseltinib is an orally bioavailable inhibitor of the tyrosine kinase receptor colony stimulating factor 1 receptor (CSF1R; CSF-1R; C-FMS; CD115; M-CSFR), with …
TREOSULFAN
It’s only fair to share… TREOSULFAN C6H14O8S2 MW 278.29 FDA APPROVED 1/21/2025 Grafapex CAS 299-75-2 Treosulfan299-75-2TreosulphanOvastatTreosulfano NSC-39069 [(2S,3S)-2,3-dihydroxy-4-methylsulfonyloxybutyl] methanesulfonate Trecondi, Treosulfan was authorized for medical use in the European Union in June 2019 For use in combination with fludarabine as a preparative regimen for allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia and myelodysplastic …
Bevemipretide
It’s only fair to share… Bevemipretide, CAS 2356106-71-1 FREE BASE CAS SBT-272 Trihydrochloride, 2589640-11-7 607.7 g/mol, C31H45N9O4 F553HAL9V8 Phase IAmyotrophic lateral sclerosis 18 Sep 2024Pharmacodynamics data from a preclinical trial in dry age related macular degenration released by Stealth BioTherapeutics The present technology relates generally to compounds (i.e. peptidomimetics), compositions (e.g. medicaments) and methods for treating, …
Suzetrigine
It’s only fair to share… Suzetrigine CAS 2649467-58-1 WeightAverage: 473.4Monoisotopic: 473.137396951Chemical FormulaC21H20F5N3O4 FDA 1/30/2025, Journavx To treat moderate to severe acute painPress Release Suzetrigine, sold under the brand name Journavx, is a medication used for the management of pain.[1][2] It is a non-opioid, small-molecule analgesic that works as a selective inhibitor of Nav1.8-dependent pain-signaling pathways in the peripheral nervous system,[3][4] avoiding the addictive potential of opioids. Suzetrigine is taken by mouth.[1] The …
BENZGALANTAMINE
It’s only fair to share… BENZGALANTAMINE CAS 224169-27-1 Benzgalantamine gluconate, 1542321-58-3 6h-benzofuro(3a,3,2-ef)(2)benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, benzoate (ester), (4as,6r,8as)- Formula C24H25NO4 Molar mass 391.467 g·mol−1 External IDs GLN-1062 gluconate UNIILN7PMJ4P57 CAS Number1542321-58-3 WeightAverage: 587.622Monoisotopic: 587.236661015 Chemical FormulaC30H37NO11 Benzgalantamine, sold under the brand name Zunveyl, is a medication used for the treatment of mild to moderate dementia of the Alzheimer’s type.[1] It is a cholinesterase inhibitor.[1] Benzgalantamine …
Tisolagiline
It’s only fair to share… Tisolagiline CAS 1894207-44-3 PCH79KLX33 (2S)-2-[[4-[4-(trifluoromethyl)phenyl]phenyl]methylamino]propanamide 322.32 g/mol SCHEME Tisolagiline (INNTooltip International Nonproprietary Name; developmental code names KDS-2010, SeReMABI) is a potent, highly selective, and reversible monoamine oxidase B (MAO-B) inhibitor which is under development for the treatment of Alzheimer’s disease and obesity.[1][2][3][4] It is taken by mouth.[1] Tisolagiline is being developed by NEUROBiOGEN and Scilex Bio.[1][2] As of December 2024, it is in phase 2 clinical trials for Alzheimer’s disease and …
Bemfivastatin, PPD 10558, RBx 10558
It’s only fair to share… Bemfivastatin, PPD 10558, RBx 10558 cas 805241-79-6 Molecular Weight 588.67 Formula C34H37FN2O6 Bemfivastatin (PPD 10558) is an orally active, HMG-CoA Reductase (HMGCR) inhibitor, also known as Statin. Bemfivastatin enhances the activity of liver extraction. Bemfivastatin exhibits little developmental toxicity effects in pregnant rats and rabbits via daily oral doses during organogenesis …
Umifoxolaner, ML 878
It’s only fair to share… Umifoxolaner, ML 878 CAS 2021230-37-3 Molecular Weight 643.86 Formula C26H16ClF10N3O3 umifoxolaner (ML-878) is a γ-aminobutyric acid (GABA) regulated chloride channels antagonist. Umifoxolaner is an anti-parasitic agent Animals such as mammals and birds are often susceptible to parasite infestations/infections. These parasites may be ectoparasites, such as insects, and endoparasites such as filariae and …
Bavtavirine
It’s only fair to share… Bavtavirine, CAS 1956373-71-9 C26H20N6 416.48 Benzonitrile, 4-[[4-amino-8-[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]-2-quinazolinyl]amino]- Gilead Sciences, Inc.; Institute of Organic Chemistry and Biochemistry of the AS CR, v.v.i. Bavtavirine is a potent non-nucleoside reverse transcriptase inhibitors (NNRTIs). Bavtavirine is part of highly active antitiretroviral therapy (HAART) treatment regimen. Bavtavirine can be used for HIV disease research. SCHEME PATENT WO2016105564 https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016105564&_cid=P11-M8QXHF-67832-1 A …
Uplarafenib
It’s only fair to share… Uplarafenib 1425485-87-5 494.5 g/mol Molecular Formula C22H21F3N4O4S Molecular Weight 494.487 UPLARAFENIB is a small molecule drug with a maximum clinical trial phase of II and has 1 investigational indication. Neupharma, Inc. There are at least 400 enzymes identified as protein kinases. These enzymes catalyze the phosphorylation of target protein substrates. The …