TILOGLIPTIN

It’s only fair to share… PRESENTING 2 MOLECULES………..I AM NOT SURE WHICH IS TITLE MOLECULE EMAIL ME amcrasto@gmail.com Molecular Formula: C25H27N7O Molecular Weight: 441.539 g/mol 2-[(3R)-3alpha-Aminopiperidino]-3-(2-butynyl)-5-(4-methyl-2-quinazolinylmethyl)-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-4-one CAS 1428445-40-2 REF Bioorganic & Medicinal Chemistry (2013), 21(7), 1749-1755.   NEXT ONE……………… CAS 1415912-31-0 1H-Purine-2,6-dione, 8-[(3R)-3-amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-([1,2,5]thiadiazolo[3,4-b]pyridin-5-ylmethyl)- 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-([1,2,5]thiadiazolo[3,4-b]pyridin-5-ylmethyl)-1H-purine-2,6-dione 8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-([1,2,5]thiadiazolo[3,4-b]pyridin-5-ylmethyl)purine-2,6-dione Molecular Formula: C21H23N9O2S Molecular Weight: 465.536 g/mol REF CN 102807568, CN 105315301,  WO 2016019868 Salt……….. CAS 1874255-95-4 C21 H23 N9 O2 …

TEGAFUR

It’s only fair to share… Tegafur CAS 17902-23-7 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)- Molecular Weight,200.17, MF C8 H9 F N2 O3 172-173 °C Miyashita, Osamu; Chemical & Pharmaceutical Bulletin 1981, 29(11), PG 3181-90 Uracil, 5-fluoro-1-(tetrahydro-2-furyl)- Utefos Venoterpine WY1559000 YR0450000 5-fluoro-1-tetrahydrofuran-2-ylpyrimidine-2,4(1H,3H)-dione Carzonal N1-(2′-Furanidyl)-5-fluorouracil Synonyms:Ftorafur ATC:L01BC03 EINECS:241-846-2 LD50:800 mg/kg (M, i.v.); 775 mg/kg (M, p.o.); 685 mg/kg (R, i.v.); 930 …

FDA approves first generic Strattera (atomoxetine) for the treatment of ADHD

It’s only fair to share… FDA approves first generic Strattera (atomoxetine) for the treatment of ADHD 05/30/2017 04:49 PM EDT The U.S. Food and Drug Administration today approved the first generic versions of Strattera (atomoxetine) to treat attention-deficit/hyperactivity disorder (ADHD) in pediatric and adult patients. 05/30/2017 The U.S. Food and Drug Administration today approved the …

FDA approves first drug Actemra (tocilizumab) to specifically treat giant cell arteritis

It’s only fair to share… FDA approves first drug to specifically treat giant cell arteritis 05/22/2017 The U.S. Food and Drug Administration today expanded the approved use of subcutaneous Actemra (tocilizumab) to treat adults with giant cell arteritis. This new indication provides the first FDA-approved therapy, specific to this type of vasculitis. May 22, 2017 …

Linrodostat BMS 986205

It’s only fair to share… cas 2221034-29-1 Linrodostat (2R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide Linrodostat mesylate Linrodostat [USAN] UNII-OS7OBU191R OS7OBU191R Linrodostat mesylate [USAN] BMS-986205-04 2221034-29-1 Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-alpha- methyl-, (alphaR,1alpha,4alpha)-, methanesulfonate (1:1) Linrodostat; (2R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide; Linrodostat mesylate; Linrodostat [USAN]; UNII-OS7OBU191R; OS7OBU191R   BMS 986205 (2R)-N-(4-Chlorophenyl)-2-[cis-4-(6-fluoro-4-quinolinyl)cyclohexyl]propanamide Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methyl-, cis- Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methyl-, cis-(αR)- (i?)-N-(4-chlorophenyl)-2- c 5-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide CAS: 1923833-60-6 Phase III Head and neck cancer; Malignant melanoma BMS-986205, ONO-7701,  …

Metopimazine

It’s only fair to share… Metopimazine RP-9965, EXP-999, NG-101 l-(3-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]propyl)-4-piperidinecarboxamide CAS 14008-44-7 MF C22 H27 N3 O3 S2 MW 445.60 4-Piperidinecarboxamide, 1-[3-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]propyl]- Isonipecotamide, 1-[3-[2-(methylsulfonyl)phenothiazin-10-yl]propyl]- (7CI,8CI) 1-[3-[2-(Methylsulfonyl)-10H-phenothiazin-10-yl]propyl]-4-piperidinecarboxamide 1-[3-[2-(Methylsulfonyl)phenothiazin-10-yl]propyl]-4-piperidinecarboxamide 1-[3-[2-(Methylsulfonyl)phenothiazin-10-yl]propyl]isonipecotamide 2-Methylsulfonyl-10-[3-(4-carbamoylpiperidino)propyl]phenothiazine EXP 999 Metopimazine RP 9965 Vogalene metopimazine (gastroparesis), Neurogastrx Sanofi (Originator) Teva Treatment of Nausea and Vomiting, APPROVED Dopamine D3 receptor antagonist; Dopamine D2 receptor antagonist Gastroprokinetic Metopimazine …

2-pyrazolin-5-one

It’s only fair to share… 137-45-1 cas 3-Pyrazolin-5-one (8CI) Pyrazol-3(or 5)-ol (6CI,7CI) 1,2-Dihydro-3H-pyrazol-3-one 1,2-Dihydropyrazol-3-one 1H-Pyrazol-3-ol 1H-Pyrazol-5-ol 3-Hydroxypyrazole 3-Pyrazoline-5-one 3-Pyrazolone 4-Pyrazolin-3-one NSC 520837 Pyrazol-3-ol Pyrazol-5-ol   Compound 1: Under stirring, to a solution of 5.81 g (50 mmol) of methyl (2E)-3-methoxyacrylate in methanol (5 mL) was hydrazine hydrate (2.75 g, 55 mmol) added and the mixture …

3-(2-(Benzoylamino)ethyl)-1-phenyl-1H-pyrazol-5-yl benzoate

It’s only fair to share… 3-(2-(Benzoylamino)ethyl)-1-phenyl-1H-pyrazol-5-yl benzoate (14). Benzoyl chloride (0.230 mL, 2 mmol) was added to a stirred suspension of amine 6c (276 mg, 1 mmol) in a mixture of anhydrous dichloromethane (10 mL) and 4-methylmorpholine (0.66 mL, 6 mmol) and the mixture was stirred at r.t. for 12 h. Volatile component were evaporated …