Tag «AMVUTTRA»

Vutrisiran sodium, ALN 65492, Votrisiran

It’s only fair to share… RNA, (Um-sp-(2′-deoxy-2′-fluoro)C-sp-Um-Um-Gm-(2′-deoxy-2′-fluoro)G-Um-Um-(2′-deoxy-2′-fluoro)A-Cm-Am-Um-Gm-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)A-Um-Cm-Cm-Cm-Am-sp-Um-sp-Cm), complex with RNA (Um-sp-Gm-sp-Gm-Gm-Am-Um-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)U-Gm-Um-Am-Am-Cm-Cm-Am-Am-Gm-Am) 3′-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] (1:1) Vutrisiran Sodium Nucleic Acid Sequence Sequence Length: 44, 23, 2113 a 9 c 8 g 14 umultistranded (2); modified Vutrisiran sodium ALN 65492 Votrisiran C530H672F9N171Na43O323P43S6 : 17289.77 [1867157-35-4 , Vutrisiran] Formula C530H672F9N171O323P43S6.43Na  OR C530H672F9N171Na43O323P43S6 CAS 1867157-35-4 , VURISIRAN Mol weight 17289.7661 FDA APPROVED, AMVUTTRA, 2022/6/13 …