Tag «Migraine»

Ubrogepant, MK-1602

It’s only fair to share…   Ubrogepant, MK-1602 (S)-N-((3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)-2′-oxo-1′,2′,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3′-pyrrolo[2,3-b]pyridine]-3-carboxamide (3’S)-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl]-2′-oxo-1′,2‘,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3′-pyrrolo[2,3-b]pyridine]-3-carboxamide (6S)-N-[(3S,5S,6R)-6-Methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl]-2′-oxo-1′,2′,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3′-pyrrolo[2,3-b]pyridine]-3-carboxamide Spiro[6H-cyclopenta[b]pyridine-6,3′-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide, 1′,2′,5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl]-2′-oxo-, (6S)- CAS: 1374248-77-7 Chemical Formula: C29H26F3N5O3 Molecular Weight: 549.5542 UNII-AD0O8X2QJR CAS TRIHYDRATE 1488325-95-6 CAS MONOHYDRATE 1488327-13-4 Originator Merck & Co Class Amides; Antimigraines; Fluorine compounds; Small molecules; Spiro compounds Mechanism of Action Calcitonin gene-related peptide receptor antagonists Phase III Migraine, Allergan Most Recent Events 01 Sep 2016 Allergan initiates a …