It’s only fair to share… Tolebrutinib SAR442168 Treatment of Multiple Sclerosis (MS) CAS 1971920-73-6 PRN 2246, example 3 [WO2016196840A1] C26H25N5O3, 455.5 GTPL10625 BTK’168 EX-A4699 BDBM50557487 WHO 11268 4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-prop-2-enoylpiperidin-3-yl]imidazo[4,5-c]pyridin-2-one 4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-prop-2-enoylpiperidin-3-yl]imidazo[4,5-c]pyridin-2-one (R)-1-(1-Acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one 4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-(prop-2- enoyl)piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5- 2H-Imidazo(4,5-C)pyridin-2-one, 4-amino-1,3-dihydro-1-((3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl)-3-(4-phenoxyphenyl)- 4-Amino-1,3-dihydro-1-((3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl)-3-(4-phenoxyphenyl)-2H-imidazo(4,5-C)pyridin-2-one Tolebrutinib (R&D code SAR442168), developed by Principia and later acquired by Sanofi and included in its product line, Tolebrutinib is a …
Tag «multiple sclerosis»
Pepinemab, VX 15
It’s only fair to share… (Heavy chain) QVQLVQSGAE VKKPGSSVKV SCKASGYSFS DYYMHWVRQA PGQGLEWMGQ INPTTGGASY NQKFKGKATI TVDKSTSTAY MELSSLRSED TAVYYCARYY YGRHFDVWGQ GTTVTVSSAS TKGPSVFPLA PCSRSTSEST AALGCLVKDY FPEPVTVSWN SGALTSGVHT FPAVLQSSGL YSLSSVVTVP SSSLGTKTYT CNVDHKPSNT KVDKRVESKY GPPCPPCPAP EFLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSQEDPE VQFNWYVDGV EVHNAKTKPR EEQFNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKGLPSSI EKTISKAKGQ PREPQVYTLP PSQEEMTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSRLTV DKSRWQEGNV FSCSVMHEAL HNHYTQKSLS LSLGK (Light chain) DIVMTQSPDS …
Cladribine, クラドリビン
It’s only fair to share… Cladribine クラドリビン Leustatin クラドリビン RWJ 26251 / RWJ-26251 Molecular FormulaC10H12ClN5O3 Average mass285.687 Da 2-chloro-6-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine 2-Chlorodeoxyadenosine 4291-63-8 [RN] 6997 adenosine, 2-chloro-2′-deoxy- [ACD/Index Name] AU7357560 CDA (2R,3S,5R)-5-(6-Amino-2-chlor-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol Leustatin (Trade name) Litak (Trade name) MLS000759397 Movectro (Trade name) Mylinax QA-1968 LAUNCHED, 1993, USA Ortho Biotech, Janssen Biotech Cladribine, sold under the brand name Leustatin and Mavenclad among others, is a medication used to …
FDA approves new drug to treat multiple sclerosis Ocrevus (ocrelizumab)
It’s only fair to share… FDA approves new drug to treat multiple sclerosis 03/29/2017 On March 28, the U.S. Food and Drug Administration approved Ocrevus (ocrelizumab) to treat adult patients with relapsing forms of multiple sclerosis (MS) and primary progressive multiple sclerosis (PPMS). This is the first drug approved by the FDA for PPMS. Ocrevus …