It’s only fair to share… Bedaquiline fumarate; Bedaquiline (fumarate); Cas 845533-86-0; UNII-P04QX2C1A5; P04QX2C1A5; Bedaquiline fumarate (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol;(E)-but-2-enedioic acid R 207910 TMC 207 Molecular Formula: C36H35BrN2O6 Molecular Weight: 671.588 g/mol Product SIRTURO (Janssen Products) Formula C32H31BrN2O2. C4H4O4 CAS 845533-86-0 FUMARATE FREE FORM 843663-66-1 Mol weight 671.5769 2018/1/19 PMDA JAPAN APPROVED Bedaquiline fumarate Sirturo Janssen Pharmaceutical ベダキリンフマル酸塩 Bedaquiline …
Monthly archives: March, 2018
Baloxavir marboxil, バロキサビルマルボキシル , балоксавир марбоксил , بالوكسافير ماربوكسيل , 玛巴洛沙韦 ,
It’s only fair to share… Baloxavir marboxil バロキサビルマルボキシル балоксавир марбоксил [Russian] [INN] بالوكسافير ماربوكسيل [Arabic] [INN] 玛巴洛沙韦 [Chinese] [INN] Carbonic acid, [[(12aR)-12-[(11S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-3,4,6,8,12,12a-hexahydro-6,8-dioxo-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl]oxy]methyl methyl ester ({(12aR)-12-[(11S)-7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl}oxy)methyl methyl carbonate (((12aR)-12-((11S)-7,8-Difluoro-6,11-dihydrodibenzo(b,E)thiepin-11-yl)-6,8-dioxo-3,4,6,8,12,12ahexahydro-1H-(1,4)oxazino(3,4-C)pyrido(2,1-F)(1,2,4)triazin-7-yl)oxy)methyl methyl carbonate Carbonic acid, (((12aR)-12-((11S)-7,8-difluoro-6,11-dihydrodibenzo(b,E)thiepin-11-yl)-3,4,6,8,12,12a-hexahydro-6,8-dioxo-1H-(1,4)oxazino(3,4-C)pyrido(2,1-F)(1,2,4)triazin-7-yl)oxy)methyl methyl ester Antiviral In Japan the product is indicated for treatment influenza types A and B in adults and children RG-6152 UNII-505CXM6OHG Originator Shionogi Developer Roche; Shionogi Class Antivirals; Dibenzothiepins; Esters; …
ELECLAZINE, элеклазин , إيليكلازين , 依来克秦 , REVISITED
It’s only fair to share… ELECLAZINE GS-6615 Molecular Formula: C21H16F3N3O3 Molecular Weight: 415.372 g/mol 1443211-72-0 4-(pyrimidin-2-ylmethyl)-7-[4-(trifluoromethoxy)phenyl]-2,3-dihydro-1,4-benzoxazepin-5-one 4-(pyrimidin-2-ylmethyl)-7-[4-(trifluoromethoxy)phenyl]-2,3,4,5- tetrahydro-1,4- benzoxazepin-5-one 7-(4-(Trifluoromethoxy)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one 1,4-Benzoxazepin-5(2H)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4-(trifluoromethoxy)phenyl]- Eleclazine; UNII-PUY08529FK; 1443211-72-0; GS-6615; PUY08529FK; 4-(pyrimidin-2-ylmethyl)-7-(4-(trifluoromethoxy)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-on элеклазин [Russian] [INN] إيليكلازين [Arabic] [INN] 依来克秦 [Chinese] [INN] Phase III Long QT syndrome INGREDIENT UNII CAS Eleclazine Hydrochloride 4R1JP3Q4HI 1448754-43-5 Eleclazine has been used in trials studying the treatment of LQT2 Syndrome, Long …
Fosravuconazole L-lysine ethanolate, ホスラブコナゾール L－リシンエタノール付加物
It’s only fair to share… C23H20F2N5O5PS▪C6H14N2O2▪C2H6O : 739.73 [914361-45-8] [(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1,2,4-triazol-1-yl)butan-2-yl]oxymethyl dihydrogen phosphate;(2S)-2,6-diaminohexanoic acid;ethanol L-Lysine [[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-yl]oxy]methyl dihydrogen phosphate ethanol BFE-1224 BMS-379224 E-1224 ravuconazole prodrugs, ravuconazole methyl phosphate fosravuconazole bis(L-lysine) ホスラブコナゾール L－リシンエタノール付加物 Formula C23H20F2N5O5PS. C6H14N2O2. C2H6O CAS 914361-45-8 Mol weight 739.727 Antifungal, Ergosterol biosynthesis inhibitor Fungal infection; Onychomycosis; Trypanosoma cruzi infection PMDA JAPAN APPROVED 2018/1/19 PMDA APPROVED Fosravuconazole L-lysine ethanolate Nailin …
METHYL 2-(ACETYLTHIO)ACETATE
It’s only fair to share… Methyl 2-(methylthio)acetate Molecular FormulaC4H8O2S Average mass120.170 Da 16630-66-3 S-Methylthioglycolate DOI: 10.1021/acs.oprd.7b00378 //////////////// It’s only fair to share…
S-Acetylation of Thiols Mediated by Triflic Acid: A Novel Route to Thioesters
It’s only fair to share… This paper demonstrates an efficient, mild, and chemoselective synthesis of various thioesters via a HOTf-catalyzed S-acetylation of aromatic and aliphatic thiols using isopropenyl acetate as a cheap and convenient acetylating agent. During our tests, we also investigated the differences between the activities of metal triflates and triflic acid as catalysts …
FDA approves new HIV treatment Trogarzo (ibalizumab-uiyk) for patients who have limited treatment options
It’s only fair to share… FDA approves new HIV treatment Trogarzo (ibalizumab-uiyk),for patients who have limited treatment options Today, the U.S. Food and Drug Administration approved Trogarzo (ibalizumab-uiyk), a new type of antiretroviral medication for adult patients living with HIV who have tried multiple HIV medications in the past (heavily treatment-experienced) and whose HIV infections …