It’s only fair to share… ELUBIOL Dichlorophenyl imidazoldioxolan CAS 67914-69-6 AMY 925C27H30Cl2N4O5, 561.5 g/mol ethyl 4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-1-carboxylate Elubiol (Dichlorophenyl imidazoldioxolan) has moderate sebum-inhibiting activity and can be used in the treatment of oily skin or dandruff. SCHEME PATENT DE2804096 https://patentscope.wipo.int/search/en/detail.jsf?docId=DE102084041&_cid=P20-MB323Q-91006-1 PATENT US4358449 https://patentscope.wipo.int/search/en/detail.jsf?docId=US37288536&_cid=P20-MB3265-92366-1 PATENT CN102070620 https://patentscope.wipo.int/search/en/detail.jsf?docId=CN84648943&_cid=P20-MB329Q-94515-1 Example 1 According to the method of the present invention, bacteriostatic …
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Elfucose
It’s only fair to share… Elfucose Cas 87-96-7 Chemical Formula: C6H12O5Exact Mass: 164.07Molecular Weight: 164.157 L-fucopyranose (6-deoxy-L-galactopyranose) (3S,4R,5S,6S)-6-methyloxane-2,3,4,5-tetrol Fucose is under investigation in clinical trial NCT03354533 (Study of ORL-1F (L-fucose) in Patients With Leukocyte Adhesion Deficiency Type II). L-fucopyranose is the pyranose form of L-fucose. It has a role as an Escherichia coli metabolite and …
Durlobactam
It’s only fair to share… Durlobactam CAS 1467829-71-5 WeightAverage: 277.25Monoisotopic: 277.03685626 Chemical FormulaC8H11N3O6S Ingredient UNII CAS InChI Key Durlobactam sodium F78MDZ9CW9 1467157-21-6 WHHNOICWPZIYKI-IBTYICNHSA-M FDA 5/23/2023, Xacduro, To treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia caused by susceptible isolates of Acinetobacter baumannii-calcoaceticus complexPress ReleaseDrug Trials Snapshots (2S,5R)-2-CARBAMOYL-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL SULFATE SULFURIC ACID, MONO((2S,5R)-2-(AMINOCARBONYL)-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL) ESTERETX 2514, ETX-2514, ETX2514, WHO …
Edelinontrine
It’s only fair to share… Edelinontrine CRD740, PF04447943, cas 1082744-20-4 Molecular Weight 395.46 Formula C20H25N7O2 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(oxan-4-yl)-5H-pyrazolo[3,4-d]pyrimidin-4-one Edelinontrine (PF-04447943) is a potent inhibitor of human recombinant PDE9A (IC50=12 nM) with >78-fold selectivity, respectively, over other PDE family members (IC50>1000 nM). PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor (Ki of 2.8, 4.5 and 18 nM) for human, rhesus and …
Sulbactam
It’s only fair to share… Sulbactam Ingredient UNII CAS InChI Key Sulbactam benzathine 49MU89FVBV 83031-43-0 YSEPFTSCLHUBNH-HFKSPEPWSA-N Sulbactam sodium DKQ4T82YE6 69388-84-7 NKZMPZCWBSWAOX-IBTYICNHSA-M 68373-14-8 (free acid) WeightAverage: 233.242Monoisotopic: 233.035793157 Chemical FormulaC8H11NO5S (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Betamaze, Penicillanic Acid Sulfone, Sulbactamum, CP 45899, CP-45899, CP45899 FDA 2023, Xacduro, 5/23/2023, To treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia caused by …
Eclitasertib
It’s only fair to share… Eclitasertib CAS 2125450-76-0 5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydropyrido[3,2-b][1,4]oxazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide Molecular Weight 378.38 Formula C19H18N6O3 SAR443122, was investigated in several clinical trials to evaluate its safety and efficacy. NCT04469621 was studied in severe COVID-19 patients, while NCT05588843 is currently recruiting participants with ulcerative colitis. Additionally, NCT04781816, which was completed with results, focused on patients with cutaneous …
Perfluorhexyloctane
It’s only fair to share… WeightAverage: 432.269Monoisotopic: 432.112266666Chemical FormulaC14H17F13 Perfluorhexyloctane 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane FDA APPROVED 8/16/2023, Sohonos, To reduce the volume of new heterotopic ossification in adults and pediatric patients (aged 8 years and older for females and 10 years and older for males) with fibrodysplasia ossificans progressivaDrug Trials Snapshot Perfluorohexyloctane is a fluoroalkane that is tetradecane in which …
DIMDAZENIL
It’s only fair to share… DIMDAZENIL CAS 308239-86-3 WeightAverage: 372.81Monoisotopic: 372.1101515 Chemical FormulaC17H17ClN6O2 EVT-201, 308239-86-3, EVT201, 6J8AF7CLE4, EVT 201 7-Chloro-3-[5-[(dimethylamino)methyl]-1,2,4-oxadiazol-3-yl]-4,5-dihydro-5-methyl-6H-imidazo[1,5-a] [1,4]benzodiazepin-6-one 7-chloro-3-[5-[(dimethylamino)methyl]-1,2,4-oxadiazol-3-yl]-5-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one EVT 201 is a novel partial positive allosteric modulator of the GABAA receptor complex which is being developed as a treatment for insomnia. It is being developed by Evotec Inc. Dimdazenil, sold under …
Digadoglucitol
It’s only fair to share… Digadoglucitol DA-52534 CAS 2098944-37-5 μ-[2,2′,2”,2”’,2””,2””’-({[(2S,3R,4R,5R)-2,3,4,5,6- pentahydroxyhexyl]azanediyl}bis{[2-(hydroxy-κO)propane3,1-diyl]-1,4,7,10-tetraazacyclododecane-10,1,4,7-tetraylκ4 N1 ,N4 ,N7 ,N10})hexa(acetato-κO)]digadolinium diagnostic agent C40H69Gd2N9O19 MW 1,294.536 F2Q2ZU6CAU SCHEME PATENT Bracco Imaging SpA WO2017098044 https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2017098044&_cid=P12-MAUH6W-49653-1 PATENT WO2023006722 https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2023006722&_cid=P12-MAUHGF-56290-1 PATENT WO2022023240 .///////////Digadoglucitol, F2Q2ZU6CAU, X RAY CONTRAST AGENT, DA-52534, DA 52534 It’s only fair to share…
Tofersen
It’s only fair to share… all-P-ambo-2′-O-(2-Methoxyethyl)-5-methyl-P-thiocytidylyl-(3’→5′)-2′-O-(2-methoxyethyl)adenylyl-(3’→5′)-2′-O-(2-methoxyethyl)-P-thioguanylyl-(3’→5′)-2′-O-(2-methoxyethyl)guanylyl-(3’→5′)-2′-O-(2-methoxyethyl)-P-thioadenylyl-(3’→5′)-P-thiothymidylyl-(3’→5′)-2′-deoxy-P-thioadenylyl-(3’→5′)-2′-deoxy-5-methyl-P-thiocytidylyl-(3’→5′)-2′-deoxy-P-thioadenylyl-(3’→5′)-P-thiothymidylyl-(3’→5′)-P-thiothymidylyl-(3’→5′)-P-thiothymidylyl-(3’→5′)-2′-deoxy-5-methyl-P-thiocytidylyl-(3’→5′)-P-thiothymidylyl-(3’→5′)-2′-deoxy-P-thioadenylyl-(3’→5′)-2′-O-(2-methoxyethyl)-5-methylcytidylyl-(3’→5′)-2′-O-(2-methoxyethyl)-P-thioadenylyl-(3’→5′)-2′-O-(2-methoxyethyl)guanylyl-(3’→5′)-2′-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3’→5′)-2′-O-(2-methoxyethyl)-5-methyluridine C230H317N72O123P19S15 : 7127.86[2088232-70-4] Tofersen CAS 2088232-70-4 FDA APPROVED 4/25/2023, Qalsody To treat amyotrophic lateral sclerosis in adults who have a SOD1 gene mutationDrug Trials Snapshot A nucleic acid-based drug indicated for the treatment of a specific type of amyotrophic lateral sclerosis. Tofersen, sold under the brand name Qalsody, is a medication used for the …