It’s only fair to share… Atigliflozin CAS 647834-15-9 Chemical Formula: C18H22O7S Exact Mass: 382.1086 Molecular Weight: 382.43 AVE 2268; AVE-2268; AVE2268; Y0H7UPE4WJ (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-((2-(4-methoxybenzyl)thiophen-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol Atigliflozin (AVE-2268) is an orally active and selective SGLT-2 inhibitor, with IC50s of 10 nM and 8.2 μM for hSGLT-2 and hSGLT-1) respectively. Atigliflozin can lower the blood glucose and improve the impaired oral glucose tolerance. …
Category «ANTI DIABETIS»
Mizagliflozin
It’s only fair to share… Mizagliflozin WeightAverage: 564.68Monoisotopic: 564.315914393 Chemical FormulaC28H44N4O8 2,2-dimethyl-3-[3-[3-methyl-4-[[5-propan-2-yl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1H-pyrazol-4-yl]methyl]phenoxy]propylamino]propanamide Mizagliflozin is an SGLT1 inhibitor developed as a potential treatment for chronic constipation.[1][2] It progressed as far as Phase II trials in humans but was not approved for medical use, however it has since been investigated for other applications.[3][4] MIZAGLIFLOZIN is a small molecule drug with a maximum …
Henagliflozin
It’s only fair to share… Henagliflozin, SHR-3824 , CAS 1623804-44-3 C22-H24-Cl-F-O7, 454.8756 PHASE 2 for the treatment of type 2 diabetes China 20222, approvals 2022 HengRui (Originator) Jiangsu Hengrui Medicine Co Ltd UNII-21P2M98388; 21P2M98388; Henagliflozin; SHR3824; SHR-3824; HENAGLIFLOZIN PROLINE 4IO819SW6M 570.0 g/mol C27H33ClFNO9 (1R,2S,3S,4R,5R)-5-[4-chloro-3-[(4-ethoxy-3-fluorophenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol;(2R)-pyrrolidine-2-carboxylic acid In April 2016, Jiangsu Hengrui Medicine is developing henagliflozin (phase 2 …
Velagliflozin
It’s only fair to share… Velagliflozin 2-[(4-cyclopropylphenyl)methyl]-4-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]benzonitrile Velagliflozin L-proline H2O Velagliflozin, sold under the brand name Senvelgo, is an antidiabetic medication used for the treatment of cats.[2][4][5] Velagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor.[6] It is taken by mouth.[2] Velagliflozin is the active ingredient of the first oral liquid medication approved by the Food and Drug Administration for the treatment of …
Chiglitazar
It’s only fair to share… Chiglitazar CAS 743438-45-1 Ingredient UNII CAS InChI Key Chiglitazar sodium, (S)- YN12H6OCV6 2390374-10-2 RMVIEXHXRDCWBT-UCRKPPETSA-M Chiglitazar was developed by Chipscreen Biosciences and was approved in China for improving glycemic control in adultpatients with type2 diabetes in October2021. Chiglitazar (trade name Bilessglu) is a drug for the treatment of type 2 diabetes.[1] It is a peroxisome proliferator-activated …
Imeglimin hydrochloride
It’s only fair to share… Meglimin hydrochloride Twymeeg Formula C6H13N5. HCl CAS 775351-61-6 (HCl). , C6H14ClN5 191.66 CAS 775351-65-0, FREEFORM 155.20 Mol weight 191.6619 AntidiabeticAPPROVED PMDA JAPAN2021/6/23, イメグリミン塩酸塩 (4R)-6-N,6-N,4-trimethyl-1,4-dihydro-1,3,5-triazine-2,6-diamine DB12509 NCGC00378621-02 HY-14771 Q6003719 UNII-UU226QGU97 UU226QGU97 1,3,5-Triazine-2,4-diamine,1,6-dihydro-N,N,6-trimethyl-,(+)-(9CI) (4R)-6-N,6-N,4-trimethyl-1,4-dihydro-1,3,5-triazine-2,6-diamine Imeglimin [INN] Emd 387008 (R-imeglimin) HCl EMD-387008 Imeglimin is an experimental drug being developed as an oral anti-diabetic.[1][2] It is an oxidative phosphorylation blocker that …