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Glycopyrronium bromide, гликопиррония бромид , بروميد غليكوبيرونيوم , 格隆溴铵 , グリコピロニウム臭化物

It’s only fair to share… Glycopyrronium bromide гликопиррония бромид [Russian] [INN] بروميد غليكوبيرونيوم [Arabic] [INN] 格隆溴铵 [Chinese] [INN] グリコピロニウム臭化物 Cas 596-51-0, 3-Hydroxy-1,1-dimethylpyrrolidinium bromide α-cyclopentylmandelate (6CI,7CI) Pyrrolidinium, 3-[(cyclopentylhydroxyphenylacetyl)oxy]-1,1-dimethyl-, bromide (9CI) Pyrrolidinium, 3-hydroxy-1,1-dimethyl-, bromide, α-cyclopentylmandelate (8CI) 1,1-Dimethyl-3-hydroxypyrrolidinium bromide α-cyclopentylmandelate AHR-504 Asecryl Copyrrolate Gastrodyn Glycopyrrolate Glycopyrrolate bromide Glycopyrrone bromide Glycopyrronium bromide NSC 250836 NSC 251251 NSC 251252 NVA 237 Nodapton Robanul Robinul Seebri Tarodyl …

Vericiguat, ベルイシグアト

It’s only fair to share… Vericiguat BAY 102; BAY-1021189; MK-1242 1350653-20-1 Chemical Formula: C19H16F2N8O2 Molecular Weight: 426.3878 Vericiguat; 1350653-20-1; UNII-LV66ADM269; Methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate; BAY-1021189; LV66ADM269 Methyl (4,6-diamino-2-(5-fluoro-1-((2-fluorophenyl)methyl)-1H-pyrazolo(3,4-b)pyridin-3-yl(pyrimidin-5-yl)carbamate methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate Methyl{4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridi- n-3-yl]pyrimidin-5-yl}carbamate Originator Bayer HealthCare Pharmaceuticals Developer Bayer HealthCare Pharmaceuticals; Merck & Co Mechanism of Action Guanylate cyclase stimulants Phase III Chronic heart failure Phase I Coronary artery disease 28 May 2018 Phase …

Ferric Maltol, マルトール第二鉄

It’s only fair to share… Ferric Maltol Iron, tris(3-hydroxy-2-methyl-4H-pyran-4-onato-O3,O4)- Molecular Formula: C18H15FeO9 Molecular Weight: 431.154 g/mol iron(3+);2-methyl-4-oxopyran-3-olate RN: 33725-54-1 UNII: MA10QYF1Z0 Feraccru Ferric maltol; UNII-MA10QYF1Z0; MA10QYF1Z0; Ferric maltol (INN); Ferric maltol [INN]; 33725-54-1 Shield Therapeutics, under license from Vitra Pharmaceuticals NDA filing expected in US in 2H 2018, Ph 3 trial is planned in 2018/19 for treatment of …

Daprodustat, ダプロデュスタット

It’s only fair to share… Daprodustat, GSK1278863 ダプロデュスタット CAS 960539-70-2 GSK1278863; GSK 1278863; GSK-1278863; Daprodustat C19H27N3O6 Exact Mass: 393.18999 (1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine N-[(l,3-dicyclohexyl-6-hydroxy-2,4-dioxo-l,2,3,4- tetrahydro-5-pyrimidinyl)carbonyl]glycine 2-(1,3-dicyclohexyl-2,4,6-triohexahydropyrimidine-5-carboxamide acetic acid Mechanism of Action: HIF-prolyl hydroxylase inhibitor Indication: anemia, diabetic wounds, and reduction of ischemic complications Development Stage: Phase II Developer:GlaxoSmithKline UNII:JVR38ZM64B ダプロデュスタット Daprodustat C19H27N3O6 : 393.43 [960539-70-2] Daprodustat , also known as …

Dasotraline, ダソトラリン

It’s only fair to share… (1R,4S)-4-(3,4-Dichlorphenyl)-1,2,3,4-tetrahydro-1-naphthalinamine 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-, (1R,4S)- [ACD/Index Name] 4D28EY0L5T 675126-05-3 [RN] 9885 SEP-225289 UNII:4D28EY0L5T (1R,4S)-N-DESMETHYL SERTRALINE (1R,4S)-trans-norsertraline (1R,4S)-trans-norsertraline|SEP-225289 Dasotraline; 675126-05-3; UNII-4D28EY0L5T; (1R,4S)-trans-Norsertraline; Norsertraline, (1R,4S)-trans-; SEP-225289 ダソトラリン SEP-225289; SEP-289, DSP-225289 Dasotraline,  SEP-225289, DSP-225289   1R,4S Transnorsertraline Generic Name:Dasotraline Synonym: SEP-225289 Chemical Name:(1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine 4(S)-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1(R)-ylamine hydrochloride CAS Number:675126-05-3, Cas of THE DRUG SUBSTANCE hydrochloride is 675126-08-6 Indication:Attention deficit hyperactivity disorder (ADHD) Drug …

LAFUTIDINE, ラフチジン

It’s only fair to share…   LAFUTIDINE N-[4-[4-(Piperidin-1-ylmethyl)pyridin-2-yloxy]-(Z)-but-2-en-1-yl]-2-(furfurylsulfinyl)acetamide FRG-8813 ATC:A02B Use:antisecretory, gastric H2-antagonist (+)-2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]acetamide Formula:C22H29N3O4S MW:431.56 g/mol CAS-RN:118288-08-7 (±)-2-(Furfurylsulfinyl)-N-(4-(4-(piperidinomethyl)-2-pyridyl)oxy-(Z)-2-butenyl)acetamide (Z)-2-((2-Furanylmethyl)sulfinyl)-N-(4-((4-(1-piperidinylmethyl)-2-pyridinyl)oxy)-2-butenyl)acetamide 118288-08-7 FRG‐8813、2‐(Furfurylsulfinyl)‐N‐[(Z)‐4‐[[4‐(piperidinomethyl)‐2‐pyridinyl]oxy]‐2‐butenyl]acetamide、ロクチジン、Loctidine、ラフチジン・・・ 2-[(furan-2-ylmethyl)sulfinyl]-N-[(2Z)-4-{[4-(piperidin-1-ylmethyl)pyridin-2-yl]oxy}but-2-en-1-yl]acetamide 49S4O7ADLC 7173 Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]- [ACD/Index Name] lafutidine [INN] [Wiki] UNII:49S4O7ADLC (Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide Lafutidine , also named N-[4-[4-(piperidin-1-ylmethyl)pyridin-2-yloxy]-(Z)-but-2-en-1-yl]-2-(furfurylsulfinyl)acetamide, is a histamine H2 receptor antagonist that was first produced in Japan by Taiho and UCB Japan for the oral treatment …

Plazomicin sulfate, プラゾマイシン硫酸塩 ,

It’s only fair to share… Plazomicin Molecular FormulaC25H48N6O10 Average mass592.683 Da (2S)-4-Amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R)-3-amino-6-{[(2-hydroxyéthyl)amino]méthyl}-3,4-dihydro-2H-pyran-2-yl]oxy}-2-{[3-désoxy-4-C-méthyl-3-(méthylamino)-β-L-arabinopyranosyl]oxy}-3-hyd roxycyclohexyl]-2-hydroxybutanamide [French][ACD/IUPAC Name] 1154757-24-0 [RN] 9522 ACHN-490 Plazomicin Sulfate Molecular Formula: C25H50N6O14S Molecular Weight: 690.763 g/mol Plazomicin Sulfate; UNII-A78L6MT746; Plazomicin Sulfate [USAN]; A78L6MT746; 1380078-95-4; Plazomicin sulfate (USAN), ACHN 490 sulfate 6′-(hydroxylethyl)-1-(haba)-sisomicin Plazomicin is a neoglycoside antibiotic with activity against a broad range of Gram-positive and Gram-negive …

Inotersen sodium, イノテルセンナトリウム

It’s only fair to share… Inotersen sodium, UNII: 950736UC77 Data Source for DNA, d(P-thio)((2′-O-(2-methoxyethyl))m5rU-(2′-O-(2-methoxyethyl))m5rC-(2′-O-(2-methoxyethyl))m5rU-(2′-O-(2-methoxyethyl))m5rU-(2′-O-(2-methoxyethyl))rG-G-T-T-A-m5C-A-T-G-A-A-(2′-O-(2-methoxyethyl))rA-(2′-O-(2-methoxyethyl))m5rU-(2′-O-(2-methoxyethyl))m5rC-(2′-O-(2-methoxyethyl))m5rC-(2′-O-(2-methoxyethyl))m5rC) STR  https://chem.nlm.nih.gov/chemidplus/rn/1432726-13-0 IUPAC Condensed Thy-MeOEt(-2)Ribf-sP-m5Cyt-MeOEt(-2)Ribf-sP-Thy-MeOEt(-2)Ribf-sP-Thy-MeOEt(-2)Ribf-sP-Gua-MeOEt(-2)Ribf-sP-dGuo-sP-dThd-sP-dThd-sP-dAdo-sP-m5Cyt-dRibf-sP-dAdo-sP-dThd-sP-dGuo-sP-dAdo-sP-dAdo-sP-Ade-MeOEt(-2)Ribf-sP-Thy-MeOEt(-2)Ribf-sP-m5Cyt-MeOEt(-2)Ribf-sP-m5Cyt-MeOEt(-2)Ribf-sP-m5Cyt-MeOEt(-2)Ribf.19Na+ IUPAC O2′-(2-methoxyethyl)-5-methyl-P-thio-uridylyl-(3′->5′)-O2′-(2-methoxyethyl)-5-methyl-P-thio-cytidylyl-(3′->5′)-O2′-(2-methoxyethyl)-5-methyl-P-thio-uridylyl-(3′->5′)-O2′-(2-methoxyethyl)-5-methyl-P-thio-uridylyl-(3′->5′)-O2′-(2-methoxyethyl)-P-thio-guanylyl-(3′->5′)-2′-deoxy-P-thio-guanylyl-(3′->5′)-P-thio-thymidylyl-(3′->5′)-P-thio-thymidylyl-(3′->5′)-2′-deoxy-P-thio-adenylyl-(3′->5′)-2′-deoxy-5-methyl-P-thio-cytidylyl-(3′->5′)-2′-deoxy-P-thio-adenylyl-(3′->5′)-P-thio-thymidylyl-(3′->5′)-2′-deoxy-P-thio-guanylyl-(3′->5′)-2′-deoxy-P-thio-adenylyl-(3′->5′)-2′-deoxy-P-thio-adenylyl-(3′->5′)-O2′-(2-methoxyethyl)-P-thio-adenylyl-(3′->5′)-O2′-(2-methoxyethyl)-5-methyl-P-thio-uridylyl-(3′->5′)-O2′-(2-methoxyethyl)-5-methyl-P-thio-cytidylyl-(3′->5′)-O2′-(2-methoxyethyl)-5-methyl-P-thio-cytidylyl-(3′->5′)-O2′-(2-methoxyethyl)-5-methyl-cytidine sodium salt イノテルセンナトリウム Formula C230H299N69O121P19S19. 19Na Cas 1432726-13-0 Antisense oligonucleotide; TTR mRNA Mol weight 7600.7669 ClassAntisense oligonucleotides; Neuroprotectants Mechanism of ActionPrealbumin expression inhibitors Orphan Drug StatusYes – Amyloid polyneuropathy New Molecular Entity Yes Highest Development Phases RegisteredAmyloid polyneuropathy …

Amfonelic acid, амфонеловая кислота , حمض أمفونيليك , 安福萘酸 , アンホネル酸

It’s only fair to share… Amfonelic acid Molecular FormulaC18H16N2O3 Average mass308.331 Da 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-4-oxo-7-(phenylmethyl)- 15180-02-6 [RN] 1-Ethyl-1,4-dihydro-4-oxo-7-(phenylmethyl)-1,8-naphthyridine-3-carboxylic Acid 2324 RR302AR19Y NSC 100638 амфонеловая кислота [Russian] [INN] حمض أمفونيليك [Arabic] [INN] 安福萘酸 [Chinese] [INN] Lopac0_000416 MFCD00055095 [MDL number] NCA NSC-100638 UNII:RR302AR19Y UNII-RR302AR19Y Win 25,978 Amfonelic acid (AFA; WIN 25,978) is a research chemical and dopaminergic stimulant with antibiotic properties.[1] History The stimulant properties of AFA were discovered serendipitously at Sterling-Winthrop in the midst of …

BENFOTIAMINE, бенфотиамин , بينفوتيامين , 苯磷硫胺 ,  ベンフォチアミン 

It’s only fair to share…   Benfotiamine S-[(Z)-2-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-5-phosphonooxypent-2-en-3-yl] benzenecarbothioate Benphothiamine; Betivina; Biotamin; Neurostop; Nitanevril; cas 22457-89-2 C19H23N4O6PS MF 466.447882 g/mol MW Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propenyl] ester (9CI) Benzoic acid, thio-, S-ester with N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide dihydrogen phosphate (ester) (8CI) Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)-, S-benzoate O-(dihydrogen phosphate) (8CI) 8088CB BTMP Benfothiamine Benfotiamine Benzoylthiamine O-monophosphate Benzoylthiamine monophosphate Berdi Betivina Bietamine Biotamin Milgamma N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide S-benzoate O-phosphate Neurostop Nitanevril S-Benzoylthiamine O-monophosphate S-Benzoylthiamine monophosphate Tabiomyl Vitanevril …