It’s only fair to share… Benzonatate Molecular FormulaC30H53NO11 Average mass603.742 Da 104-31-4 [RN] 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-yl 4-(butylamino)benzoate бензонатат بنزوناتات 苯佐那酯 ベンゾナテート; KM 65 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl 4-(butylamino)benzoate 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-(butylamino)benzoate Benzonatate bulk and Benzonatate capsules 100mg, cdsco india 2021, 15.07.2021 For the treatment of refractory cough CAS Registry Number: 104-31-4 CAS Name: 4-(Butylamino)benzoic acid 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester Additional Names: nonaethyleneglycol monomethyl ether p-n-butylaminobenzoate; p-butylaminobenzoic acid w-O-methylnonaethyleneglycol ester; benzononatine …
Category «Uncategorized»
ABX 464
It’s only fair to share… ABX-464 Molecular FormulaC16H10ClF3N2O Averrage mass338.712 Da SPL-464 1258453-75-6 [RN] 26RU378B9V 2-Quinolinamine, 8-chloro-N-[4-(trifluoromethoxy)phenyl]- 8-Chloro-N-[4-(trifluoromethoxy)phenyl]-2-quinolinamine EX-A3322, DB14828, SB18690, BS-14770 Abivax is developing ABX464 a lead from HIV-1 splicing inhibitors, which modulates biogenesis of viral RNA, and acts by targeting the Rev protein, for treating HIV infection, rheumatoid arthritis, ulcerative colitis and COVID-19 infection. In August 2021, …
THIAMINE, VIT B1
It’s only fair to share… THIAMINE Molecular FormulaC12H17N4OS Average mass265.354 Da 59-43-8 has cl atom 70-16-6 [RN] no cl atom Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, hydrochloride (1:1:1), Thiamine CL hcl, 67-03-8, (Component: 70-16-6) 1;1;1, C12 H17 N4 O S . Cl H . Cl 3595616 [Beilstein] 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium thiamin hydrochloride Vitamin B1 hydrochloride thiamine hydrochloride aneurin hydrochloride 3-(4-amino-2-methyl-5-pyrimidinyl)methyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride hydrochloride Thiamine CAS Registry Number: 59-43-8 CAS …
Tegoprazan
It’s only fair to share… Tegoprazan RN: 942195-55-3 UNII: W017G7IF4S ROTATION (-) Molecular Formula, C20-H19-F2-N3-O3, Molecular Weight, 387.3841 (S)-4-(5,7-difluorochroman-4-yloxy)-N,N,2-trimethyl-lH-benzo[d]imidazole-6-carboxamide). 1H-Benzimidazole-5-carboxamide, 7-(((4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl)oxy)-N,N,2-trimethyl- 7-(((4S)-5,7-Difluoro-3,4-dihydro-2H-chromen-4-yl)oxy)-N,N,2-trimethyl-1H-benzimidazole-5-carboxamide (S)-4-((5,7-difluorochroman-4-yl)oxy)-N,N,2-trimethyl-1H-benzo(d)imidazole-6-carboxamide HK inno.N/RaQualia Pharma Alternative Names: CJ-12420; IN-A001; K-CAB; LXI-15028; RQ-00000004; RQ-4 Тегопразан [Russian] [INN] تيغوبرازان [Arabic] [INN] 替戈拉生 [Chinese] [INN] A novel Potassium-competitive acid blocker. OriginatorPfizer Tegoprazan, a reversible H+/K+-ATPase inhibitor developed by CJ Healthcare (now inno.N), was first approved and …
FLUVATINIB
It’s only fair to share… 4-(2-Fluoro-3chloro-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]-2-fluorophenoxy]-7-methoxy- N-(4-(6-Aminocarbonyl-7-methoxyquinolin-4-yl)oxy-2-chloro-3-fluorophenyl)-N’-cyclopropylurea cas 2304405-29-4 C21 H18 Cl F N4 O4 444.84 CN109134365 discloses an active compound or medicinal salt with multi-target effects of VEGFR1~3, fibroblast growth factor receptor 1~3, RET, Kit and PDGFR, and its chemical structure formula is as follows: Formula I: Chemical name: 4-(2-Fluoro-3chloro-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinoline carboxamide, the drug name is …
Difelikefalin acetate
It’s only fair to share… Difelikefalin acetate ジフェリケファリン酢酸塩 CAS 1024829-44-4 Formula C36H53N7O6. (C2H4O2)x D-Phe-D-Phe-D-Leu-D-Lys-[ω(4-aminopiperidine-4- carboxylic acid)]-OH FDA APPROVED, 2021/8/23, FORSUVA Analgesic, Antipruritic, Opioid receptor agonist Treatment of moderate-to-severe pruritus associated with chronic kidney disease in adults undergoing hemodialysis Difelikefalin, CR-845; MR-13A-9; MR-13A9 4-amino-1- (D-phenylalanyl-D-phenylalanyl-D-leucyl-D-lysyl) piperidine-4-carboxylic acid C36H53N7O6, 679.40573 ORIGINATOR Ferring Pharmaceuticals DEVELOPER Cara Therapeutics CLASS Analgesic …
Pepinemab, VX 15
It’s only fair to share… (Heavy chain) QVQLVQSGAE VKKPGSSVKV SCKASGYSFS DYYMHWVRQA PGQGLEWMGQ INPTTGGASY NQKFKGKATI TVDKSTSTAY MELSSLRSED TAVYYCARYY YGRHFDVWGQ GTTVTVSSAS TKGPSVFPLA PCSRSTSEST AALGCLVKDY FPEPVTVSWN SGALTSGVHT FPAVLQSSGL YSLSSVVTVP SSSLGTKTYT CNVDHKPSNT KVDKRVESKY GPPCPPCPAP EFLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSQEDPE VQFNWYVDGV EVHNAKTKPR EEQFNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKGLPSSI EKTISKAKGQ PREPQVYTLP PSQEEMTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSRLTV DKSRWQEGNV FSCSVMHEAL HNHYTQKSLS LSLGK (Light chain) DIVMTQSPDS …
AVASOPASEM MANGANESE
It’s only fair to share… AVASOPASEM Average: 518.83 Monoisotopic: 517.134397 Chemical FormulaC21H35Cl3MnN5 manganese(2+);(4S,9S,14S,19S)-3,10,13,20,26-pentazatetracyclo[20.3.1.04,9.014,19]hexacosa-1(26),22,24-triene;dichloride Manganese, dichloro((4aS,13aS,17aS,21aS)-1,2,3,4,4a,5,6,12,13,13a,14,15,16,17,17a,18,19,20,21,21a-eicosahydro-7,11-nitrilo-7H-dibenzo(b,H)-5,13,18,21-tetraazacycloheptadecine-kappaN5,kappaN13,kappaN18,kappaN21,kappaN22)-, (pb-7-11-2344’3′)- CAS 435327-40-5 A superoxide dismutase mimetic. GC 4419 M-40419 SC-72325A For the Reduction of The Severity and Incidence of Radiation and Chemotherapy-Induced Oral Mucositis Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) …
Belzutifan
It’s only fair to share… Belzutifan CAS 1672668-24-4 383.34 g·mol−1 C17H12F3NO4S 3-[[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-methylsulfonyl-2,3-dihydro-1H-inden-4-yl]oxy]-5-fluorobenzonitrile MK-6482, PT-2977, UNII-7K28NB895L, 7K28NB895L 3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile 3-{[(1s,2s,3r)-2,3-Difluoro-1-Hydroxy-7-(Methylsulfonyl)-2,3-Dihydro-1h-Inden-4-Yl]oxy}-5-Fluorobenzonitrile GTPL11251, PT 2977 [WHO-DD], BDBM373040 FDA APPROVED 8/13/2021, Welireg To treat von Hippel-Lindau disease under certain conditions EMA Drug Information Disease/Condition Treatment of von Hippel-Lindau disease Active Substance 3-(((1S,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile Status of Orphan Designation Positive Decision Date 2020-08-21 FDA approves belzutifan for cancers associated with von Hippel-Lindau disease On …
Naftopidil
It’s only fair to share… Naftopidil 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol C24H28N2O3, 392.49 CAS 57149-07-2 KT-611, Flivas, Avishot 1-(4-(2-methoxyphenyl)piperazin-1-yl)-3-(naphthalen-1-yloxy)propan-2-ol Naftopidil (Flivas), BM-15275 Naftopidil CAS Registry Number: 57149-07-2 CAS Name: 4-(2-Methoxyphenyl)-a-[(1-naphthalenyloxy)methyl]-1-piperazineethanol Additional Names: RS-1-[4-(2-methoxyphenyl)-1-piperazinyl]-3-(1-naphthoxy)-2-propanol; 1-(2-methoxyphenyl)-4-[3-(naphth-1-yloxy)-2-hydroxypropyl]-piperazine Manufacturers’ Codes: KT-611 Trademarks: Avishot (Kanebo); Flivas (Asahi) Molecular Formula: C24H28N2O3 Molecular Weight: 392.49 Percent Composition: C 73.44%, H 7.19%, N 7.14%, O 12.23% Literature References: a1-Adrenergic blocker and serotonin (5HT1A) receptor agonist. Prepn: E. C. Witte et al., DE 2408804; eidem, US 3997666 (1975, 1976 …